Pediatric Demyelinating Diseases of the Central Nervous System and Their Mimics : A Case-Based Clinical Guide / edited by Emmanuelle Waubant, Timothy E. Lotze.

Format:

Book

Contributor:

Waubant, Emmanuelle., Editor.

Lotze, Timothy E., Editor.

Language:

English

Subjects (All):

Neurology.

Pediatrics.

Internal medicine.

Internal Medicine.

Local Subjects:

Neurology.

Pediatrics.

Internal Medicine.

Physical Description:

1 online resource (XV, 347 p. 166 illus., 24 illus. in color.)

Edition:

1st ed. 2017.

Place of Publication:

Cham : Springer International Publishing : Imprint: Springer, 2017.

Summary:

This collection of pediatric clinical cases focus on multiple sclerosis, neuromyelitis optica, acute disseminated encephalomyelitis and mimics. Dedicated sections on diseases affecting the brain, brainstem, spinal cord and the optic nerve feature chapters that include the diagnostic work up, therapeutic management and case outcome. Typical and atypical presentations of various pediatric demyelinating diseases also emphasize therapy response and those that breakthrough on treatment. Filling a critical gap in the literature on inflammatory disorders of the central nervous system, all those that treat patients with these rare and challenging disorders will find this book extremely helpful for their daily clinical practice.

Contents:

SECTION I: Diseases that Affect the Brain

1. Acute Disseminated Encephalomyelitis

2. Acute Necrotizing Encephalopathy mimicking ADEM

3. Pediatric Multiple Sclerosis Manifesting with Primary Psychiatric Symptoms

4. Multiple Sclerosis in the Extremely Young

5. Breakthrough Disease in Pediatric MS

6. Neuromyelitis Optica Spectrum Disorder with Neuropsychiatric Presentation

7. Pediatric Tumefactive Demyelination

8. Radiologically Isolated Syndrome

9. Anti-Glutamic Acid Decarboxylase Limbic Encephalitis

10. Anti-NMDA Receptor Antibody Encephalitis

11. Pediatric Central Nervous System Vasculitis

12. Neuroinflammatory disease in association with Morphea (Localized Scleroderma)

13. Susac’s Syndrome

14. Infectious Mimics of Multiple Sclerosis

15. Central nervous system lymphoma

16. Methotrexate Toxicity

17. Alexander Disease Type II

18. Neurodegenerative Langerhans Cell Histiocytosis

19. X-linked Adrenoleukodystrophy

20. Rapid-onset Obesity with Hypothalamic dysfunction, Hypoventilation and Autonomic Dysregulation (ROHHAD)

21. ADEM Mimic with Thiamine Transporter Deficiency

SECTION II: Diseases that Affect the Brainstem

22. Acute Disseminated Encephalomyelitis-Brainstem and Cerebellar Presentation

23. Multiple Sclerosis with Brainstem Presentation

24. Neuromyelitis Optica Spectrum Disorder with Brainstem Presentation

25. Infection mimics with brainstem presentation

26. Chronic Lymphocytic Inflammation with Pontine Perivascular Enhancement Responsive to Steroids

SECTION III: Diseases that Affect the Spinal Cord

27. Acute Disseminated Encephalomyelitis with Spinal Cord Presentation

28. Post-Infectious Acute Transverse Myelitis

29. Complete transverse myelitis (idiopathic)

30. Transverse Myelitis with Acute Inflammatory Polyradiculoneuropathy

31. Acute Flaccid Myelitis

32. Neuromyelitis optica spectrum disease with transverse myelitis presentation

33. Transverse myelitis in lupus

34. Acute Demyelination associated with TNF alpha- inhibiting biologic therapy

35. Myelopathy due to occult trauma mimicking transverse myelitis

36. Hypomyelination with Brainstem and Spinal Cord Abnormalities and Leg Spasticity (HBSL)

SECTION IV: Diseases That Affect the Optic Nerve

37. Acute disseminated encephalomyelitis followed by recurrent or monophasic optic neuritis

38. Chronic Relapsing Inflammatory Optic Neuropathy (CRION)

39. Optic Neuritis as the Presenting Symptom for MS

40. Steroid Dependent Recurrent Optic Neuritis in Pediatric Multiple Sclerosis

41. Neuromyelitis optica presenting with bilateral optic neuritis

42. Sarcoidosis with Optic Nerve Presentation.

Notes:

Includes bibliographical references at the end of each chapters and index.

ISBN:

3-319-61407-X