Neural mechanisms of addiction / edited by Mary Torregrossa.

Format:

Book

Contributor:

Torregrossa, Mary, editor.

Language:

English

Subjects (All):

Neuropsychiatry.

Drug addiction--Psychological aspects.

Drug addiction.

Physical Description:

1 online resource (308 pages)

Edition:

1st ed.

Place of Publication:

London, United Kingdom : Academic Press, an imprint of Elsevier, [2019]

Summary:

Neural Mechanisms of Addiction is the only book available that synthesizes the latest research in the field into a single, accessible resource covering all aspects of how addiction develops and persists in the brain. The book summarizes our most recent understanding on the neural mechanisms underlying addiction. It also examines numerous biobehavioral aspects of addiction disorders, such as reinforcement learning, reward, cognitive dysfunction, stress, and sleep and circadian rhythms that are not covered in any other publication. Readers with find the most up-to-date information on which to build a foundation for their future research in this expanding field. Combining chapters from leading researchers and thought leaders, this book is an indispensable guide for students and investigators engaged in addiction research.

Contents:

Introduction to the neural basis of addiction

Animal models of addiction

Transcriptional and epigenetic regulation and reward circuitry in drug addiction

Neural circuit plasticity in addiction

Glutamatergic neuroplasticity in addiction

Fos-expressing neuronal ensembles in addiction research

Interoceptive stimulus effects of drugs of abuse

Maladaptive memory mechanisms in addiction and relapse

Neural morphology and addiction

Mechanisms regulating compulsive drug behaviors

Role of stress-associated signaling in addiction

Negative reinforcement mechanisms in addiction

Circadian rhythms and addiction

Role of Oxytocin in countering addiction-associated behaviors exacerbated by stress

The role of norepinephrine in drug addiction: past, present, and future

Glial disregulation in addiction

Role of the extracellular matrix in addiction

Striatal cell-tyle specific plasticity in addiction

Harnessing circuits for the treatment of addictive disorders

Conclusions and future directions.

Notes:

Description based on print version record.

ISBN:

9780128123317

0128123311

9780128122020

0128122021