Addictive substances and neurological disease : alcohol, tobacco, caffeine, and drugs of abuse in everyday lifestyles / edited by Ronald Ross Watson, University of Arizona, Arizona Health Sciences Center, Tucson, AZ, USA, Sherma Zibadi, Department of Pathology, University of South Florida Medical School, Tampa, FL, USA.

Format:

Book

Contributor:

Watson, Ronald R. (Ronald Ross), editor.

Zibadi, Sherma, editor.

Series:

Gale eBooks

Language:

English

Subjects (All):

Substance abuse--Physiological aspects.

Substance abuse.

Substance abuse--Psychological aspects.

Drugs of abuse--Physiological effect.

Drugs of abuse.

Nervous system--Diseases.

Nervous system.

Physical Description:

1 online resource (xv, 398 pages) : illustrations (chiefly color)

Place of Publication:

London : Academic Press, an imprint of Elsevier, [2017]

Summary:

Addictive Substances and Neurological Disease: Alcohol, Tobacco, Caffeine, and Drugs of Abuse in Everyday Lifestyles is a complete guide to the manifold effects of addictive substances on the brain, providing readers with the latest developing research on how these substances are implicated in neurological development and dysfunction. Cannabis, cocaine, and other illicit drugs can have substantial negative effects on the structure and functioning of the brain. However, other common habituating and addictive substances often used as part of an individual's lifestyle, i.e., alcohol, tobacco, caffeine, painkillers can also compromise brain health and effect or accentuate neurological disease. This book provides broad coverage of the effects of addictive substances on the brain, beginning with an overview of how the substances lead to dysfunction before examining each substance in depth. It discusses the pathology of addiction, the structural damage resulting from abuse of various substances, and covers the neurobiological, neurodegenerative, behavioral, and cognitive implications of use across the lifespan, from prenatal exposure, to adolescence and old age. This book aids researchers seeking an understanding of the neurological changes that these substances induce, and is also extremely useful for those seeking potential treatments and therapies for individuals suffering from chronic abuse of these substances.-- Source other than Library of Congress.

Contents:

Acute ethanol-induced changes in microstructural and metabolite concentrations on the brain: noninvasive functional brain Imaging

Prenatal alcohol exposure and neuroglial changes in neurochemistry and behavior in animal models

Alcohol on histaminergic neurons of brain

Antenatal alcohol and histological brain disturbances

Alcohol intoxication and traumatic spinal cord injury: basic and clinical science

Visual and auditory changes after acute alcohol ingestion

Zebrafish models of alcohol addiction

Effect of alcohol on the regulation of a-Synuclein in the human brain

Consumption of ethanol and tissue changes in the central nervous system

Ethanol consumption and cerebellar disorders

Gene expression in CNS regions of genetic rat models of alcohol abuse

Role of TLR4 in the ethanol-induced modulation of the autophagy pathway in the brain

Cholinergic signaling in ethanol reward

Alcoholic neurological syndromes

Frontal lobe dysfunction after developmental alcohol exposure: implications from animal models

Ethanol's action mechanisms in the brain: from lipid general alterations to specific protein receptor binding

Antioxidant vitamins and brain dysfunction in alcoholics

Serotonin deficiency and alcohol use disorders

Functional reorganization of reward- and habit-related brain networks in addiction

Ethanol: neurotoxicity and brain disorders

Functionally relevant brain alterations in polysubstance users: differences to monosubstance users, study challenges, and implications for treatment

Deep brain stimulation: a possible therapeutic technique for treating refractory alcohol and drug addiction behaviors

Understanding the roles of genetic and environmental influences on the neurobiology of nicotine use

Tobacco smoke and nicotine: neurotoxicity in brain development

Paradise lost: a new paradigm for explaining the interaction between neural and psychological changes in nicotine addiction patients

Interactions of alcohol and nicotine: CNS sites and contributions to their co-abuse

Role of basal forebrain in nicotine alcohol co-abuse

Chronic and acute nicotine exposure versus placebo in smokers and nonsmokers: a systematic review of resting-state fMRI studies

Novel psychoactive substances: a new behavioral and mental health threat

Cholesterol and caffeine modulate alcohol actions on cerebral arteries and brain

Sleep, caffeine, and physical activity in older adults

Ketamine: neurotoxicity and neurobehavioral disorders

Left/right hemispheric "unbalance" model in addiction.

Notes:

Includes bibliographical references at the end of each chapter and index.

Description based on print version record.

OCLC:

973537828