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An Information Technology Framework for Predictive, Preventive and Personalised Medicine : A Use-Case with Hepatocellular Carcinoma / edited by Leonard Berliner, Heinz U. Lemke.
- Format:
- Book
- Series:
- Advances in Predictive, Preventive and Personalised Medicine, 2211-3495 ; 8
- Language:
- English
- Subjects (All):
- Medical informatics.
- Data mining.
- Oncology.
- Hepatology.
- Computer simulation.
- Health Informatics.
- Data Mining and Knowledge Discovery.
- Simulation and Modeling.
- Local Subjects:
- Health Informatics.
- Data Mining and Knowledge Discovery.
- Oncology.
- Hepatology.
- Simulation and Modeling.
- Physical Description:
- 1 online resource (143 p.)
- Edition:
- 1st ed. 2015.
- Place of Publication:
- Cham : Springer International Publishing : Imprint: Springer, 2015.
- Language Note:
- English
- Summary:
- This book explores how PPPM, clinical practice, and basic research could be best served by information technology (IT). A use-case was developed for hepatocellular carcinoma (HCC). The subject was approached with four interrelated tasks: (1) review of clinical practices relating to HCC; (2) propose an IT system relating to HCC, including clinical decision support and research needs; (3) determine how a clinical liver cancer center can contribute; and, (4) examine the enhancements and impact that the first three tasks will have on the management of HCC. An IT System for Personalized Medicine (ITS-PM) for HCC will provide the means to identify and determine the relative value of the wide number of variables, including clinical assessment of the patient -- functional status, liver function, degree of cirrhosis, and comorbidities; tumor biology, at a molecular, genetic and anatomic level; tumor burden and individual patient response; medical and operative treatments and their outcomes.
- Contents:
- Preface
- Introduction
- The Digital Patient Model and Model Guided Therapy
- Hepatocellular Carcinoma and Patient Assessment
- Imaging in Hepatocellular Carcinoma: Radiologic Assessment
- Imaging in Hepatocellular Carcinoma: PET/CT
- Personalized Chemotherapy for Hepatocellular Carcinoma
- Surgical Treatment for Hepatocellular Carcinoma.- Minimally Invasive Therapies for Hepatocellular Cancer: Ablation Technologies
- Chapter 9 Minimally Invasive Therapies for Hepatocellular Cancer: Ablation Therapies
- Minimally Invasive Therapies for Hepatocellular Cancer:Catheter-Directed Therapies
- Radiation Oncology in the Treatment of Hepatocellular Carcinoma
- Design of an IT System for Hepatocellular Carcinoma
- Outlook and Expert Recommendations for Predictive, Preventive and Personalized Medicine and Hepatocellular Carcinoma.
- Notes:
- Description based upon print version of record.
- Includes bibliographical references at the end of each chapters and index.
- ISBN:
- 3-319-12166-9
- OCLC:
- 904437712
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