Pathogenesis Study of Glioma : from Glioma Stem Cells, Genomic Tags, to Rodent Models / by Hailiang Tang (editor).

Format:

Book

Contributor:

Tang, Hailiang, editor.

Language:

English

Subjects (All):

Gliomas.

Physical Description:

1 online resource (160 pages)

Other Title:

Pathogenesis Study of Glioma

Place of Publication:

[Place of publication not identified] : MDPI - Multidisciplinary Digital Publishing Institute, 2023.

Language Note:

In English.

Summary:

Despite the past two decades of research progress, glioma still remains the most challenging of all primary central nervous system (CNS) tumors. The complexity of its pathogenesis makes the disease hard to deal with, especially glioblastoma multiforme (GBM, WHO grade IV), the most aggressive brain tumor entity. This Special Issue collect studies that focus on the pathogenesis of glioma, such as its cell origin, the role of GSCs, genomic alterations, animal models, etc. We have collected 10 high-quality papers, and we welcome all researchers to read.

Contents:

Pathogenesis Study of Glioma: From Glioma Stem Cells, Genomic Tags, to Rodent Models 1

Irreversible Electroporation Mediates Glioma Apoptosis via Upregulation of AP-1 and Bim: Transcriptome Evidence 5

Multiparametric Longitudinal Profiling of RCAS-tva-Induced PDGFB-Driven Experimental Glioma 21

A Novel Necroptosis-Related Prognostic Signature of Glioblastoma Based on Transcriptomics Analysis and Single Cell Sequencing Analysis 37

PS-NPs Induced Neurotoxic Effects in SHSY-5Y Cells via Autophagy Activation and Mitochondrial Dysfunction 53

PTPRN Serves as a Prognostic Biomarker and Correlated with Immune Infiltrates in Low Grade

Glioma 67

TRP Family Genes Are Differently Expressed and Correlated with Immune Response in Glioma 81

Immune Landscape in PTEN-Related Glioma Microenvironment: A Bioinformatic Analysis 97

Safety and Efficacy of Hypofractionated Stereotactic Radiotherapy with Anlotinib Targeted Therapy for Glioblastoma at the First Recurrence: A Preliminary Report 113

Comparison of Immune Checkpoint Molecules PD-1 and PD-L1 in Paired Primary and Recurrent Glioma: Increasing Trend When Recurrence 121

Identification of an IL-4-Related Gene Risk Signature for Malignancy, Prognosis and Immune Phenotype Prediction in Glioma 139.

Notes:

Description based on publisher supplied metadata and other sources.

ISBN:

3-0365-6390-3