Exploring Psychedelics and Entactogens As Treatments for Psychiatric Disorders : Proceedings of a Workshop.

Format:

Book

Author/Creator:

National Academies of Sciences, Engineering, and Medicine.

National Academies of Sciences, Engineering, and Medicine, author.

Health and Medicine Division, author.

Board on Health Sciences Policy, author.

Forum on Neuroscience and Nervous System Disorders, author.

Contributor:

Division, Health and Medicine.

Policy, Board on Health Sciences.

Disorders, Forum on Neuroscience and Nervous System.

Stroud, Clare.

Norris, Sheena M. Posey.

Matney, Chanel.

Bain, Lisa.

Health and Medicine Division, author.

Board on Health Sciences Policy, author.

Forum on Neuroscience and Nervous System Disorders, author.

Language:

English

Subjects (All):

Psychotropic drugs.

Mental health.

Physical Description:

1 online resource (97 pages)

Edition:

1st ed.

Place of Publication:

Washington, D.C. : National Academies Press, 2023.

Summary:

Psychiatric illnesses - such as major depressive disorder, anxiety disorder, substance use disorder, and posttraumatic stress disorder (PTSD) - are widely prevalent and represent a substantial health burden worldwide. Yet, conventional medications for mental illnesses often fail to provide relief to patients' disruptive and disabling symptoms. Existing and emerging evidence that psychedelics (e.g., LSD and psilocybin) and entactogens (e.g., MDMA) may be useful as tools to alleviate mental illness has sparked a renaissance of interest by investigators, clinicians, drug developers, and patient advocates in recent years. While promising data on therapeutic efficacy has energized research and development, resolving the mechanisms of action will be important for optimizing the efficacy and safety of these medicines. Further, evaluating the effect of psychedelics and entactogens on mood and behavior comes with unique challenges still in need of resolution. These include unresolved questions relating to blinding, placebo and nocebo effects, and the impact of psychosocial contexts.In response to this renewed interest, the National Academies of Sciences, Engineering, and Medicine's Forum on Neuroscience and Nervous System Disorders convened a workshop on March 29-30, 2022. The workshop brought together a diverse group of stakeholders to explore the use of psychedelics and entactogens as treatments for psychiatric disorders. This Proceedings of a Workshop summarizes the presentations and discussions of the workshop.

Contents:

FrontMatter

Reviewers

Contents

Acronyms and Abbreviations

1 Introduction and Background

2 History and Current Status of Psychedelics and Entactogens for the Treatment of Psychiatric Disorders

3 Mechanisms of Action and Key Research Gaps for Psychedelics and Entactogens

4 Advancing Clinical Development: Challenges and Opportunities

5 Anticipating Implementation to Guide Clinical Research and Development

6 Reflecting on the Road Ahead

Appendix A: References

Appendix B: Workshop Agenda Generated by AI.

Notes:

Description based on publisher supplied metadata and other sources.

Part of the metadata in this record was created by AI, based on the text of the resource.

Other Format:

Print version: National Academies of Sciences, Engineering, and Medicine Exploring Psychedelics and Entactogens As Treatments for Psychiatric Disorders

ISBN:

9780309691406

0309691400

9780309691383

0309691389

OCLC:

1354206412