Practical lung pathology : frequently asked questions / Haodong Xu, Robert W. Ricciotti, Jose G. Mantilla, editors.

Format:

Book

Contributor:

Xu, Haodong.

Ricciotti, Robert W.

Mantilla, Jose G.

Series:

Practical anatomic pathology

Practical Anatomic Pathology

Language:

English

Subjects (All):

Lungs--Diseases--Diagnosis.

Lungs.

Physical Description:

1 online resource.

Place of Publication:

Cham, Switzerland : Springer, 2022.

Summary:

This text consists of neoplastic and non-neoplastic lung pathology. It discusses frequently encountered issues and diagnostic problems using a Q&A format and case presentations. Emphasis is placed on differentiating one from another based on the histopathological features, ancillary tests including immunohistochemical and molecular analyses, and clinical and radiologic correlation. In particular, clinical-radiologic-pathologic correlation is emphasized in the diagnosis of interstitial lung disease (ILD). This text addresses the issues and diagnostic criteria in segregating a reactive process from adenocarcinoma, poorly differentiated adenocarcinoma from poorly differentiated squamous cell carcinoma, small cell carcinoma from other types of neuroendocrine tumors, large cell carcinoma from large cell neuroendocrine carcinoma, spindle cell/sarcomatoid carcinoma from sarcomatoid mesothelioma, and carcinoma from epithelioid mesothelioma in small biopsy specimens. It also discusses key features useful for differentiating usual interstitial pneumonia (UIP) pattern from non-UIP patterns of ILD such as hypersensitivity pneumonitis, nonspecific interstitial pneumonia, and organizing pneumonia patterns in wedge biopsy specimens as well as highlights the differential diagnosis in the granulomatous inflammation. As a whole, this text answers many of the difficult questions relevant to daily practice of lung pathology. Each chapter addresses a specific diagnostic question significantly related to patients treatment options.

Contents:

Intro

Aim and Scope

Preface

Contents

Part I: Neoplastic Lung Pathology

1: Bronchial Squamous Cell Papilloma Versus Squamous Cell Carcinoma

Case Presentation

Pathologic Diagnosis: Bronchial Squamous Cell Papilloma-Negative for Severe Dysplasia and Malignancy

Key Points

What Is the Differential Diagnosis for Bronchial Squamous Cell Papilloma?

How Do I Differentiate Bronchial Squamous Cell Papilloma from Papillary Squamous Cell Carcinoma?

Are Bronchial Squamous Papilloma and Squamous Cell Carcinoma Associated with Viral Infection?

Are There Radiographic Differences Between Bronchial Squamous Cell Papilloma and Papillary Squamous Cell Carcinoma?

What Are the Clinical and Epidemiologic Differences Between Bronchial Squamous Papillomas and Primary Lung Squamous Cell Carcinomas?

References

2: Pulmonary Hamartoma Versus Chondroid Neoplasms

Pathologic Diagnosis: Pulmonary Hamartoma

What Is the Definition of a Pulmonary Hamartoma? What Are Its Clinical and Prognostic Features?

What Are the Radiographic Features of Pulmonary Hamartomas?

What Are the Pathologic Features of Pulmonary Hamartomas?

What Is the Differential Diagnosis for Pulmonary Hamartomas?

How Does One Differentiate a Predominately Chondroid Pulmonary Hamartoma from a Chondroid Neoplasm?

Are Either Chondromas or Pulmonary Hamartomas Associated with Other Conditions?

Are There Demographic Differences Between Patients with Pulmonary Chondroma and Patients with Hamartoma?

How Does One Differentiate Pulmonary Hamartoma from Chondrosarcoma?

3: Reactive Type II Pneumocyte Hyperplasia Versus Adenocarcinoma

Case Presentation

Final Pathologic Diagnosis: Reactive Type II Pneumocyte Hyperplasia in the Wedge Biopsy

Differentiation Features of Reactive Type II Pneumocyte Hyperplasia and Adenocarcinoma

Reactive Type II Pneumocyte Hyperplasia

Cytomorphology

Secondary Architectures

The Underlying Lung Injury, Background Stroma, and Inflammatory Cell Infiltrates

Ancillary Studies

4: Atypical Adenomatous Hyperplasia Versus Peribronchiolar Metaplasia

Pathologic Diagnosis: Minimally Invasive Adenocarcinoma, Acinar Pattern with Associated Lepidic Component in the Right Middle Lobe, Multifocal Adenocarcinoma In Situ, and Atypical Adenomatous Hyperplasia (AAH) in the Right Lower Lobe

What Are the Radiographic Features of Atypical Adenomatous Hyperplasia, and How Do They Differ from Peribronchiolar Metaplasia?

What Are the Gross Pathologic Features of Atypical Adenomatous Hyperplasia and Peribronchiolar Metaplasia, and in What Gross Context Are They Found?

Notes:

Includes index.

Online resource; title from PDF title page (SpringerLink, viewed November 30, 2022).

ISBN:

9783031144028

3031144023

OCLC:

1351463210

Access Restriction:

Restricted for use by site license.