Genomics and personalized medicine : what everyone needs to know / Michael Snyder.

Format:

Book

Author/Creator:

Snyder, Michael, Ph. D., author.

Series:

What everyone needs to know.

What everyone needs to know

Language:

English

Subjects (All):

Medical genetics.

Genomics.

Precision medicine.

Physical Description:

1 online resource (185 p.)

Edition:

First edition.

Place of Publication:

New York, NY : Oxford University Press, 2020.

Language Note:

English

Summary:

Today genomics, part of a larger movement toward personalized medicine, is poised to revolutionize health care. By cross-referencing an individual's genetic sequence - their genome - against known elements of 'Big Data,' elements of genomics are already being incorporated on a widespread basis, including prenatal disease screening and targeted cancer treatments. With more innovations soon to arrive at the bedside, the promise of the genomics revolution is limitless.

Contents:

Cover; GENOMICS AND PERSONALIZED MEDICINE; Copyright; Contents; Acknowledgments; Introduction; 1 Personalized Medicine; What is personalized medicine?; What personal factors impact our health?; 2 Genome Fundamentals; What is DNA?; What is a genome?; What does the genome do?; How does one person's genome differ from another person's genome?; How do genomes of men and women differ?; How is the genome decoded?; 3 An Introduction to Cancer Genetics; What is cancer and how does it arise?; How do the BRCA1 and BRCA2 genes cause cancer?; What are examples of other genes implicated in cancer?

What is a mystery genetic disease?How many Mendelian diseases are there?; How are genes responsible for genetic disorders identified?; How useful are genomic approaches to solving mystery genetic diseases?; Why can't most Mendelian diseases be solved?; 6 Complex Genetic Diseases; What is a complex genetic disease?; How does complex genetics affect neurological diseases?; How does complex genetics affect metabolic diseases?; Can some diseases be both monogenic and complex?; 7 Pharmacogenomics; How can your genome directly help guide drug treatments for treating disease?

What are other ways your DNA can guide drug treatments?Are there sex differences in drug effects?; 8 Genomics for the Healthy Person; How can getting your genome sequenced improve your health?; Can genetic testing be used to predict sports performance and injuries?; Will sequencing my genome affect my children and my relatives?; 9 Prenatal Testing; How are genome sequencing technologies changing prenatal testing?; Can genome sequencing be used to identify other mutations, beyond chromosomal abnormalities, that might cause disease?

Can genetic testing be useful for choosing healthier embryos and producing designer babies?10 Effects of the Environment on the Genome and Epigenetics; How does the environment contribute to health?; When did people first begin to study environmental effects?; When do environmental effects begin?; Can environmental factors directly impact the genome?; What is epigenetics?; What are some examples of environmental effects on physiology that are mediated through epigenetics?; What is the role of epigenetics in disease?; How will increased understanding of epigenetics impact health care?

11 Other 'Omes

Notes:

This edition previously issued in print: 2016.

Description based on publisher information.

Includes bibliographical references and index.

ISBN:

0-19-756915-3

0-19-023479-2

0-19-023478-4