Cardiovascular Signaling in Health and Disease / edited by Narasimham L. Parinandi, Thomas J. Hund.

Format:

Book

Author/Creator:

Parinandi, Narasimham L., author.

Hund, Thomas J., author.

Series:

Biomedical and Life Sciences Series

Language:

English

Subjects (All):

Biophysics.

Cell interaction.

Biomedical engineering.

Cardiovascular system.

Physiology.

Cardiography.

Molecular biology.

Clinical biochemistry.

Mechanobiological Cell Signaling.

Biomedical Engineering and Bioengineering.

Cardiovascular Physiology.

Molecular Biology.

Medical Biochemistry.

Local Subjects:

Mechanobiological Cell Signaling.

Biomedical Engineering and Bioengineering.

Cardiovascular Physiology.

Cardiography.

Molecular Biology.

Medical Biochemistry.

Physical Description:

1 online resource (535 pages)

Edition:

1st ed. 2022.

Place of Publication:

Cham : Springer International Publishing : Imprint: Springer, 2022.

Summary:

This contributed volume focuses on cardiovascular diseases (CVDs), and explores the ways in which signaling mechanisms at the biochemical, molecular, and cellular levels in the blood vessels (vascular) and heart contribute to the underlying causes of development and progression of the CVDs. This volume covers unique topics such as oxidant signaling in vascular and heart diseases and health, cytoskeletal signaling in vascular health and disease, phospholipase signaling in CVDs, lipid signaling in vascular and myocardial health and diseases, and drug discovery in cellular signaling for cardiovascular diseases. This book assembles the most important discoveries made by leaders on the cellular signaling mechanisms operating behind the development and progression of life-threatening CVDs. It is an extremely useful resource for the investigators in the field of CVDs, and opens the discussion for further discovery of efficient management and effective treatmentof the CVDs.

Contents:

Part 1: Cardiac Signaling

Chapter 1: Calcium-Dependent Signaling in Cardiac Myocytes

Chapter 2: Organization of Ca2+ Signaling Microdomains in Cardiac Myocytes

Chapter 3: Stress Kinase Signaling in Cardiac Myocytes

Chapter 4: Cardiotoxicity and cardiac cell signaling

Chapter 5: Protein Phosphatase Signaling in Cardiac Myocytes

Chapter 6: Metabolic Regulation of Mitochondrial Dynamics and Cardiac Function

Chapter 7: NADPH Oxidase System Mediates Cholesterol Secoaldehyde-Induced Oxidative Stress and Cytotoxicity in H9c2 Cardiomyocytes

Chapter 8: Lipid Mediators in Cardiovascular Physiology and Disease

Chapter 9: Cardiac Inflammasome and Arrhythmia

Chapter 10: Myocardial Fibrosis: Cell Signaling and In Vitro Modeling

Chapter 11: Neural regulation of cardiac rhythm

Part 2: Vascular Signaling

Chapter 12: Mechanisms of lipoproteins and reverse cholesterol transport in atherosclerotic cardiovascular disease

Chapter 13: Atherosclerotic plaque regression: Future perspective

Chapter 14: Role of Bioactive Lipid, Phosphatidic Acid in Hypercholesterolemia Drug-induced Myotoxicity – Statin-induced Phospholipase D (PLD) Lipid Signaling in Skeletal Muscle Cells

Chapter 15: Cell-Cell Communication in the Vascular Endothelium

Chapter 16: Lysophosphatidic acid regulates endothelial barrier integrity

Chapter 17: Regulation of Vascular Endothelial Barrier Integrity and Function by Lipid-Derived Mediators

Chapter 18: Hyperglycemic Oxoaldehyde (Glyoxal)-induced Vascular Endothelial Cell Damage through Oxidative Stress is protected by Thiol Iron Chelator, Dimercaptosuccinic Acid – Role of Iron in Diabetic Vascular Endothelial Dysfunction.

Notes:

Description based on publisher supplied metadata and other sources.

Other Format:

Print version: Parinandi, Narasimham L. Cardiovascular Signaling in Health and Disease

ISBN:

3-031-08309-1

OCLC:

1345580469