The exquisite machine : the new science of the heart / Sian E. Harding.

Format:

Book

Author/Creator:

Harding, Sian E., author.

Series:

The MIT Press

Language:

English

Subjects (All):

Heart--Diseases--Treatment.

Heart.

Heart--Diseases--Prevention.

Physical Description:

1 online resource (234 pages)

Edition:

1st ed.

Place of Publication:

Cambridge, Massachusetts : The MIT Press, [2022]

Summary:

"How the new science of the heart is using biology, engineering, and mathematics to help prevent and cure heart disease"-- Provided by publisher.

Contents:

Intro

Contents

1 Introduction

2 Threats to the Heart: A Thousand Natural Shocks

Class, Status, and Survival

Health Inequality Begins Before Birth

Adding Insult to Injury

You Are What Your Mother Ate

Victims of Our Own Success

A Constellation of Complications

3 The Science of the Really Small

It Lives! It Lives!

Harnessing the Power of the Cardiomyocyte

Setting the Rhythm

The Orchestra Plays!

The TheatRE of Biology

Seeing without Light

The Lonely Cardiomyocyte

The Marvelous Machine

4 Big Data-Many Hearts That Beat as One?

Strength in Numbers

The Story of a Life

Location, Location, Location

Natural Living-Humans in the Wild

Deep Data-a Universe within a Cell

Data Deluge and the Artificial Mind

5 The Plastic Heart

Athletes vs. the Rest of Us

Extreme Athletes-Too Much of a Good Thing?

An Uphill Struggle

Patterns of Disease

It Takes a Village

6 The Responsive Heart-Emotion in Motion

Your Secret Control Network

Your Heart Can Tell You How to Feel

Running for Your Life-the Starting Gun!

What Makes You Stronger Can Kill You as Well

Dying from a Broken Heart

The Species vs. the Individual

Should I Take Drugs to Block Adrenaline- Just in Case?

7 Can You (Not) Die of a Broken Heart?

A Missed Penalty Kick

Takotsubo-a New Broken Heart Syndrome

Sex, Drugs, and Rock 'n' Roll

Of Hot Mice and Men

Takotsubo and Sudden Cardiac Death- Two Sides of the Same Coin

What Can We Learn from Takotsubo Syndrome?

Who Will Get Takotsubo?

What's Next for the Takotsubo Patient? First Do No Harm

8 The Gendered Heart

Sex, Hormones, and Social Conditioning in Heart Disease

Genes and Sex

Stewing in the Hormone Soup

Mixing the HRT Cocktail

The Invisible Woman

The Hysterical Woman

9 The Mechanical Heart.

Keeping Up the Rhythm

Messages from the Heart

The Impossible Machine

The Gift of Life

10 Can Stem Cells Help Us Grow a New Heart?

The Healing Body-Stem Cells and You

Mix and Match?

The Therapeutic Stem Cell

Turning Back the Clock on the Heart

Own-Brand or Designer Label?

Problem #1: The Blood of Virgins Again?

Problem #2: Sorry, Your Heart Is in the Mail

Problem #3: Show Me the Money

11 When Will the Future Be Here?

The Drugs Do Work

The Gene Genie

Battles at the Cutting Edge of Gene Therapy

Muscle for the Heart

Personalized Stem Cells- the Clinical Trial in a Dish

Acknowledgments

Notes

Chapter 1

Chapter 2

Chapter 3

Chapter 4

Chapter 5

Chapter 6

Chapter 7

Chapter 8

Chapter 9

Chapter 10

Chapter 11

Index.

Notes:

OCLC-licensed vendor bibliographic record.

ISBN:

0-262-37077-8

OCLC:

1333708249