The Brain Reward System / edited by Marc Fakhoury.

Format:

Book

Contributor:

Fakhoury, Marc, Editor.

SpringerLink (Online service)

Series:

Springer Protocols (Springer-12345)

Neuromethods 1940-6045 ; 165

Neuromethods, 1940-6045 ; 165

Language:

English

Subjects (All):

Neurosciences.

Neuroscience.

Local Subjects:

Neuroscience.

Physical Description:

1 online resource (XIII, 366 pages)

Edition:

1st ed. 2021.

Contained In:

Springer Nature eBook

Place of Publication:

New York, NY : Springer US : Imprint: Humana, 2021.

System Details:

text file PDF

Summary:

This volume explores the latest techniques used to better understand the brain reward system with respect to neurotransmitters, brain structures, and connectivity. This book aims to show readers tested laboratory protocols to study neural circuitry and biological processes implicated in reward, and in neuropsychiatric disorders such as substance use disorders. The chapters are organized into four parts. Part One addresses classical techniques to study the brain reward system, including the curve shift paradigm in intracranial self-stimulation, stereotaxic surgery in rodents, and the use of brain lesions. Part Two focuses on neurochemical, behavioral, and chemogenetic techniques such as immunofluorescence for assessing adult hippocampal neurogenesis, and fast-scan voltammetry. Part Three highlights methods used to assess the rewarding potential of drugs including intracranial self-stimulation combined with drug injection, and the use of viral vectors. The Fourth Part introduces imaging and electrophysiology techniques such as positron emission tomography, in vivo electrophysiology, and fiber photometry. In the Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory. Cutting-edge and thorough, The Brain Reward System is a valuable resource for researchers interested in learning more about the current methods used to study the delineation of the brain reward system.

Contents:

Intracranial Self-Stimulation and the Curve-Shift Paradigm: A Putative Model to Study the Brain Reward System

Stereotaxic Surgery in Rodents for Stimulation of the Brain Reward System

Characterizing the Neural Substrate of Reward with the Use of Specific Brain Lesions

Assessment of Adult Hippocampal Neurogenesis: Implication for Neurodegenerative Diseases and Neurological Disorders

Fast-Scan Voltammetry for In Vivo Measurements of Neurochemical Dynamics

Carbon Fiber Probes for Real-Time Monitoring of Dopamine

Immune-to-Brain Signaling Effects on the Neural Substrate for Reward: Behavioral Models of Aversion, Anhedonia, and Despair

Behavioral Tests for Assessing Pain and Nociception: Relationship with the Brain Reward System

Chemogenetic (DREADD) Exploration of Circuits Mediating Reward-Motivated Attention

Intracranial Self-Stimulation: Using the Curve-Shift Paradigm to Assess the Abuse Potential of Drugs

Drug Self-Administration as a Model to Study the Reward System

Viral Vectors for Studying Drug-Seeking Behavior

Conditioned Place Preference Test for Assessing the Rewarding Effects of Drugs of Abuse

Positron Emission Tomography of the Reward System

In Vivo Electrophysiology for Reward Anticipation and Processing

Fiber Photometry of Neural Activity in Specific Neural Circuit

Two-Photon Microscopy for Studying Reward Circuits of the Brain. .

Other Format:

Printed edition:

ISBN:

978-1-0716-1146-3

9781071611463

Access Restriction:

Restricted for use by site license.