Stem Cells and Good Manufacturing Practices : Methods, Protocols, and Regulations / edited by Kursad Turksen.

Format:

Book

Contributor:

Turksen, Kursad, Editor.

SpringerLink (Online service)

Series:

Springer Protocols (Springer-12345)

Methods in molecular biology 1940-6029 ; 2286

Methods in Molecular Biology, 1940-6029 ; 2286

Language:

English

Subjects (All):

Stem cells.

Chemistry, Technical.

Stem Cell Biology.

Industrial Chemistry.

Local Subjects:

Stem Cell Biology.

Industrial Chemistry.

Physical Description:

1 online resource (XII, 288 pages) : 10 illustrations in color.

Edition:

2nd ed. 2021.

Contained In:

Springer Nature eBook

Place of Publication:

New York, NY : Springer US : Imprint: Humana, 2021.

System Details:

text file PDF

Summary:

This detailed book explores the utilization and delivery of stem cells for therapeutic purposes in patients in the clinic and the tightly controlled Good Manufacturing Practices (GMP) that make these powerful techniques possible. Fully updated and expanded from the first edition, this collection features a new set of protocols to arm stem cell biologists with protocols that are currently being used in a number of well-established facilities around the world. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and up to date, Stem Cells and Good Manufacturing Practices: Methods, Protocols, and Regulations, Second Edition serves as an ideal guide for researchers aiming to drive continued improvements to GMP and accelerate new stem cell treatments for patients in need.

Contents:

Swiss Fetal Transplantation Program and Non-Enzymatically Isolated Primary Progenitor Cell Types for Regenerative Medicine

GMP Tiered Cell Banking of Non-Enzymatically Isolated Dermal Progenitor Fibroblasts for Allogenic Regenerative Medicine

Progenitor Biological Bandages: An Authentic Swiss Tool for Safe Therapeutic Management of Burns, Ulcers, and Donor Site Grafts

Validation of the Media Fill Method for Solid Tissue Processing in Good Manufacturing Practice-Compliant Cell Production

The Isolation, Culturing, Cryopreservation, and the Preparation as a Final Cellular Product of the Umbilical Cord-Derived Mesenchymal Stem Cells Under Good Manufacturing Practices Conditions

The Isolation, Culture, Cryopreservation, and the Preparation as a Final Cellular Product of the Skin-Derived Fibroblasts Under Good Manufacturing Practice Conditions

The Isolation and Manufacture of GMP-Grade Bone Marrow Stromal Cells from Bone Specimens

Scalable Manufacturing of Human Hematopoietic Stem/Progenitor Cells Exploiting a Co-Culture Platform with Mesenchymal Stromal Cells

GMP-Compatible, Xeno-Free Culture of Human Induced Mesenchymal Stem Cells

GMP-Grade Methods for Cardiac Progenitor Cells: Cell Bank Production and Quality Control

Suspension Culture of Human Induced Pluripotent Stem Cells in Single-Use Vertical-WheelTM Bioreactors Using Aggregate and Microcarrier Culture Systems

Addressing Manufacturing Challenges for Commercialization of iPSC-Based Therapies

Standard Operating Procedure for the Good Manufacturing Practice-Compliant Production of Human Endometrial Stem Cells for Multiple Sclerosis

GMP-Compliant Production of Human Placenta-Derived Mesenchymal Stem Cells

GMP-Compliant Human Schwann Cells Manufacturing for Clinical Application

GMP-Compliant Adenoviral Vectors for Gene Therapy

Use of Multipotent Mesenchymal Stromal Cells, Fibrin, and Scaffolds in ihe Production of Clinical Grade Bone Tissue Engineering Products

Quality Management Systems (QMSs) of Human Tissue- and Cell-Based Product Manufacturing Facilities.

Other Format:

Printed edition:

ISBN:

978-1-0716-1327-6

9781071613276

Access Restriction:

Restricted for use by site license.