Experimental Neurotoxicology Methods / edited by Jordi Llorens, Marta Barenys.

Format:

Book

Contributor:

Llorens, Jordi, Editor.

Barenys, Marta, Editor.

SpringerLink (Online service)

Series:

Springer Protocols (Springer-12345)

Neuromethods 1940-6045 ; 172

Neuromethods, 1940-6045 ; 172

Language:

English

Subjects (All):

Neurosciences.

Medicine-Research.

Biology-Research.

Neuroscience.

Biomedical Research.

Local Subjects:

Neuroscience.

Biomedical Research.

Physical Description:

1 online resource (XVI, 491 pages) : 112 illustrations, 85 illustrations in color.

Edition:

1st ed. 2021.

Contained In:

Springer Nature eBook

Place of Publication:

New York, NY : Springer US : Imprint: Humana, 2021.

System Details:

text file PDF

Summary:

This volume explores the latest methods that seek to address the vital questions being asked in neurotoxicology research. The chapters in this book cover a variety of available methods from the molecular level to the organism level, and both in vitro and in vivo approaches, including alternative model organisms. In the Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory. Cutting-edge and authoritative, Experimental Neurotoxicology Methods is a valuable resource for both young and experienced researchers who are looking for guidance to implement these methods in their laboratories or for understanding the data generated through these techniques.

Contents:

Amino-Cupric-Silver (A-Cu-Ag) Staining to Detect Neuronal Degeneration in the Mouse Brain: The de Olmos Technique

Assessment of Auditory Hair Cell Loss by Cytocochleograms

Evaluation of Cellular and Molecular Pathology in the Rodent Vestibular Sensory Epithelia by Immunofluorescent Staining and Confocal Microscopy

Morphometric Analysis of Axons and Dendrites as a Tool for Assessing Neurotoxicity

DPOAEs for the Assessment of Noise- or Toxicant-Induced Cochlear Damage in the Rat

Use of Visual Evoked Potentials to Assess Deficits in Contrast Sensitivity in Rats following Neurotoxicant Exposures

Electrophysiological Assessments in Peripheral Nerves and Spinal Cord in Rodent Models of Chemotherapy-Induced Painful Peripheral Neuropathy

The Functional Observation Battery: Utility in Safety Assessment of New Molecular Entities

Behavioral Assessment of Vestibular Dysfunction in Rats

Assessment of Olfactory Toxicity in Dodents

Assessment of Neurotoxicant-Induced Changes in Behavior: Issues Related to Interpretation of Outcomes and Experimental Design

Assessment of Neurofilament Light Protein as a Serum Biomarker in Rodent Models of Toxic-Induced Peripheral Neuropathy

Assessing Neurotoxicant-Induced Inflammation in the Central Nervous System: Cytokine mRNA with Immunostaining of Microglia Morphology

Mitochondrial Stress Assay and Glycolytic Rate Assay in Microglia using Agilent Seahorse Extracellular Flux Analyzers

Assessment of Larval Zebrafish Locomotor Activity for Developmental Neurotoxicity Screening

A Behavioral Test Battery to Assess Larval and Adult Zebrafish after Developmental Neurotoxic Exposure

Evaluation of Neurotoxic Effects in Zebrafish Embryos by Automatic Measurement of Early Motor Behaviors

Application of Fluorescence Microscopy and Behavioral Assays to Demonstrating Neuronal Connectomes and Neurotransmitter Systems in C. elegans

Effects of Neurotoxic or Pro-Regenerative Agents on Motor and Sensory Neurite Outgrowth in Spinal Cord Organotypic Slices and DRG Explants in Culture

Integrative In Vitro/Ex Vivo Assessment of Dopaminergic Neurotoxicity in Rodents using Striatal Synaptosomes and Membrane Preparations

Quantification of Oligodendrocytes and Myelin in Human iPSC-Derived 3D Brain Cell Cultures (Brainspheres)

Measurement of Electrical Activity of Differentiated Human iPSC-Derived Neurospheres Recorded by Microelectrode Arrays (MEA).

Other Format:

Printed edition:

ISBN:

978-1-0716-1637-6

9781071616376

Access Restriction:

Restricted for use by site license.