Organ-on-a-Chip : Methods and Protocols / edited by Marco Rasponi.

Format:

Book

Contributor:

Rasponi, Marco, Editor.

SpringerLink (Online service)

Series:

Springer Protocols (Springer-12345)

Methods in molecular biology 1940-6029 ; 2373

Methods in Molecular Biology, 1940-6029 ; 2373

Language:

English

Subjects (All):

Biotechnology.

Pharmacology.

Local Subjects:

Biotechnology.

Pharmacology.

Physical Description:

1 online resource (XII, 322 pages) : 83 illustrations, 71 illustrations in color.

Edition:

1st ed. 2022.

Contained In:

Springer Nature eBook

Place of Publication:

New York, NY : Springer US : Imprint: Humana, 2022.

System Details:

text file PDF

Summary:

This book provides a collection of microphysiological systems employed for chemical/drug screening and strategies to mimic various physiological conditions. Chapters guide readers through Organ-on-a-Chip( OoC) platforms such as liver, intestine, blood-brain barrier, kidney, vessels, cardiac and skeletal muscles, articular joint, human fat. Additional chapters detail microfabrication technologies used to fabricate OoC devices such as, standard photo- and soft-lithography, techniques to fabricate membranes, and industrial-oriented fabrication methods.Written in the format of the highly successful Methods in Molecular Biology series, each chapter includes an introduction to the topic, lists necessary materials and reagents, includes tips on troubleshooting and known pitfalls, and step-by-step, readily reproducible protocols. Authoritative and cutting-edge, Organ-On-a Chip: Methods and Protocols aims to be a useful practical guide to researches to help further their study in this field.

Contents:

Photo and Soft Lithography for Organs-on-Chip applications

Organs-on-chips for Studying Tissue Barriers: Standard Techniques and a Novel Method for Including Porous Membranes Within Microfluidic Devices

Thermoplastic microfluidics

Bile Duct-On-a-Chip

Establishment of a Modular Anaerobic Human Intestine Chip

Intestinal Epithelium Tubules on a Chip

A Human Neurovascular Unit On-a-chip

Generation of a Glomerular Filtration Barrier on a Glomerulus-on-a-chip Platform

Electro-Mechanical Stimulation of 3D Cardiac Microtissues in a heart-on-chip Model

Miniaturized Vascularized Bleeding Model of Hemostasis

Fabrication and Use of a Pumpless Microfluidic Lymphatic Vessel Chip

On Chip-Platelet Activation Assessment: Microfluidic Emulation of Shear Stress Profiles Induced by Mechanical Circulatory Support Devices

Biofabrication of 3D Human Muscle Model with Vascularization and Endomysium

Mechanical induction of Osteoarthritis traits in a cartilage-on-chip model

A Synovium/Cartilage-On-A-Chip Model To Investigate The Process Of Monocyte Extravasation

A Mesoscale 3D Culture System For Native And Engineered Biphasic Tissues: Application To The Osteochondral Unit

3D biofabricated in Vitro Models of Vascularized and Mineralized Bone Tissues

Isolation, Integration, and Culture of Human Mature Adipocytes Leveraging Organ-On-Chip Technology. .

Other Format:

Printed edition:

ISBN:

978-1-0716-1693-2

9781071616932

Access Restriction:

Restricted for use by site license.