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The handbook of biological therapy : a guide to the use and safety of biological therapies in rheumatology, dermatology, and gastroenterology / Bruce Kirkham ... [et al.].
- Format:
- Book
- Language:
- English
- Subjects (All):
- Biological products--Therapeutic use.
- Biological products.
- Tumor necrosis factor--Inhibitors.
- Tumor necrosis factor.
- Physical Description:
- 1 online resource (xiv, 155 pages) : illustrations
- Edition:
- 1st ed.
- Place of Publication:
- Oxford : Oxford University Press, 2008.
- Summary:
- This book provides a comprehensive distillation of the clinical experience with Tumor Necrosis Factor (TNF) blocking therapy drugs combined with the diverse available databases to provide practical information about the use of these drugs in daily practice.
- Contents:
- Intro
- Contents
- Foreword
- Preface
- TNF - tumour necrosis factor &
- #945
- Mode of action of anti-TNF
- TNF-blocking drugs in clinical use
- TNF-blocking drugs not in clinical use
- Section 1 TNF-blocker safety
- Increased risk of infection
- Tuberculosis
- Opportunistic infections
- Injection-site reactions
- Allergic, hypersensitivity reactions, anaphylactic responses
- Psoriasis
- Infusion reactions (infliximab)
- Malignancy and lymphoproliferative conditions
- Drug-induced lupus-like reactions
- Anti-drug antibodies (immunogenicity)
- Congestive heart failure
- Neurological
- Hepatobiliary
- Use in pregnancy
- Lactation
- Respiratory
- Vaccinations
- Use of TNF-blockers with other medications
- Haematological
- Postmarketing safety experience in Crohn's disease
- Section 2 Rheumatology
- Rheumatoid arthritis
- Other rheumatological conditions
- TNF-blocking therapy in ankylosing spondylitis and psoriatic arthritis
- Ankylosing spondylitis
- Psoriatic arthritis
- Adalimumab (Humira)
- Etanercept (Enbrel)
- Infliximab (Remicade)
- Certolizumab pegol (Cimzia)
- Abatacept (Orencia)
- Anakinra (Kineret)
- B-cell depletion: Rituximab (Rituxan&
- #174
- [USA], MabThera&
- [Europe, Asia, South America])
- Section 3 Dermatology
- Approaches to management
- Assessing disease severity
- Important differences between psoriasis and rheumatoid arthritis
- Biological therapy for psoriasis
- Efalizumab (Raptiva)
- Alefacept (Amevive)
- Section 4 Gastroenterology
- Biological therapy in inflammatory bowel disease and Crohn's disease
- Natalizumab (Tysabri)
- Index
- A
- B
- C
- D
- E
- G
- H
- I
- K
- L
- M.
- N
- O
- P
- R
- S
- T
- U
- V.
- Notes:
- Includes bibliographical references and index.
- Description based on print version record.
- Description based on publisher supplied metadata and other sources.
- ISBN:
- 0-19-154897-9
- 0-19-176858-8
- 9786613893727
- 1-283-58127-2
- 978-0-1992-0816-6
- OCLC:
- 1336401642
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