Frontiers in developmental biology / edited by Robert A. Meyers.

Format:

Book

Contributor:

Meyers, Robert A. (Robert Allen), 1936- editor.

Series:

Advances in molecular biology and medicine.

Advances in molecular biology and medicine

Language:

English

Subjects (All):

Developmental biology.

Physical Description:

1 online resource (613 pages).

Edition:

1st ed.

Place of Publication:

Weinheim, Germany : Wiley-VCH Verlag GmbH & Co., [2019]

Summary:

This topical volume in the respected Encyclopedia series is the first in many years to bring together all important aspects of developmental biology in one source, from morphogenesis and organogenesis, via epigenetic regulation of gene expression to evolutionary developmental biology.

Contents:

Cover

Title Page

Copyright

Contents

Preface

Part I Introduction

Chapter 1 Developmental Cell Biology

1 Introduction

2 Historical Perspective

3 Cell Activities Underlying Development

4 Cell Differentiation

5 The Cell Cycle and Development

6 Organogenesis

7 Stem Cells

8 Cloning

9 Chimeras

10 MicroRNAs (miRNAs)

11 In-Vitro Fertilization/Nuclear Equivalence

References

Part II Evolutionary Developmental Biology

Chapter 2 Biosynthesis and Directed Evolution of Unnatural Peptides and Proteins

2 Harnessing the Diversity of RiPPs

3 Expanding the Genetic Repertoire with uAAs

4 Directed Evolution

5 Examples of Diversity Screening in RiPPs

6 Examples of Directed Evolution with uAAs

7 Therapeutic Potential and Future Perspectives for Industry

Chapter 3 Modes and Mechanisms of Speciation

2 What Are Species?

3 Classifying Barriers to Gene Flow

4 Modes of Speciation

5 Evolutionary Mechanisms Causing Population Divergence

6 Next-Generation DNA Sequencing and the Genetics of Speciation

7 Final Thoughts

Acknowledgments

Chapter 4 Molecular Darwinism: Natural Strategies of Spontaneous Genetic Variation

2 Principles of Molecular Evolution

3 Genetic Variation in Bacteria

4 Local Changes in the DNA Sequences

5 Intragenomic DNA Rearrangements

6 DNA Acquisition

7 The Three Natural Strategies Generating Genetic Variations Contribute Differently to the Evolutionary Process

8 Evolution Genes and Their Own Second-Order Selection

9 Arguments for a General Relevance of the Theory of Molecular Evolution for all Living Organisms

10 Systemic Aspects of Biological and Terrestrial Evolution

11 Conceptual Aspects of the Theory of Molecular Evolution

References.

Chapter 5 Origination, Variation, and Conservation of Animal Body Plan Development

2 Metazoan Multicellularity

3 Origins of Metazoan Body Plan Motifs

4 Vertebrate Limbs: Appendages with Body Plan-Like Properties

5 Conclusions

Chapter 6 Paleogenomics

1 Reconstructing Paleogenomes

2 Case Studies

3 Conclusions

Chapter 7 Plant Genome Surveillance by Small RNAs and Long Noncoding RNAs

2 The Often-Overlooked Role of vsiRNA Pathway in Genome Surveillance

3 Role of miRNA and tasiRNA Pathways in Plant Genome Surveillance

4 The hetsiRNA Pathway: The `Heavy Lifter' of Plant Genome Surveillance

5 An Emerging Model for the Initiation of TGS

6 Concluding Remarks

Chapter 8 RNA Protocells

2 RNA Protocells on the Prebiotic Earth: Setting the Stage

3 Sources of Organic Compounds

4 Prebiotic Compartments

5 RNA Synthesis

6 RNA Protocells in the Laboratory

7 Summary

Chapter 9 Systematics and Evolution

1 The Beginning of Molecular Systematics

2 The Molecular Assumption

3 DNA Hybridization

4 Mitochondrial DNA

5 DNA Sequences

6 Repeated (Retro)Transposons

7 "Evo-devo

8 Positional Information and Shape

9 "Mutation

10 Towards a Theory of Evolutionary Change

11 Molecules and Systematics: Looking Towards the Future

Chapter 10 The Minimal Gene-Set Machinery

2 The Present

3 Anti-TB Drug Discovery

4 Drugs in Development

Part III Cell Migration and Morphogenesis

Chapter 11 Development of the Autonomic Nervous System

2 The Sympathetic Nervous System

3 The Parasympathetic Nervous System

4 The Enteric Nervous System

5 Conclusions.

Acknowledgments

Chapter 12 Left-Right Asymmetric Morphogenesis in \textit{Drosophila} and other Invertebrates: The Discovery of Intrinsic Cell Chirality and its Functions

1 Many Animals Show Directional LR Asymmetry, the Biological Significance of Which is Often Obscure

2 Early Studies Showed an Important Role of Cilia in the LR Axis Formation in Vertebrates

3 Nodal Flow Induced by Ciliary Motion Determines the LR Axis Formation in Vertebrates

4 Beyond the Nodal Cilia Model: the Mechanisms Underlying LR Asymmetric Development in Invertebrates are Different from Those in Vertebrates

5 LR Asymmetric Development of Various Organs in \textit{Drosophila} \textit{melanogaster}

6 Handedness in \textit{Drosophila} is Not Predetermined Maternally, but Established during Embryogenesis

7 Genome-Wide Screening Identified Two Distinct Sets of Genes Required for LR-Asymmetric Development of the Anterior and Posterior Parts of the \textit{Drosophila} Embryonic Gut, Respectively

8 Genetic Pathways Required for LR Asymmetric Development of the Anterior Part of the Embryonic Gut in \textit{Drosophila}

9 Genetic Pathways Required for LR Asymmetric Development of the Posterior Part of the Embryonic Gut in \textit{Drosophila}

10 The Genetic Pathways Controlling the LR Asymmetric Development in Invertebrates may be Different from those of Vertebrates

11 Myo31DF Reverses the LR Asymmetry of Various Organs in \textit{Drosophila}

12 Factors That Interact with Myo31DF in LR-Asymmetric Development

13 Cell Chirality Drives \textit{Drosophila} LR-Asymmetric Morphogenesis

14 Cell Chirality Forms Cell-Intrinsically and is Switched to a Mirror Image by Myo31DF

15 Cell Chirality is a Common Mechanism for Inducing LR-Asymmetric Morphogenesis in \textit{Drosophila}

16 Cell Chirality may be Evolutionarily Conserved.

17 Cell Chirality versus the LR Axis

Chapter 13 Molecular Morphogenesis: Gene Expression Patterns in Animals

2 Basis of Metazoan Pattern Formation

3 Skeleton

4 Axis-Pattern Formation

5 Origin of Metazoan Pattern Formation

6 General Principles of Metazoan Pattern Formation

Part IV Gametogenesis, Fertilization and Early Embryogenesis

Chapter 14 Deciphering the Epigenetic Code of Embryonic Neurogenesis

2 Epigenetic Layers Regulating Gene Expression during Neurogenesis

3 Future Prospects

Table of Abbreviations

Chapter 15 Embryonic Patterning of the Vertebrate Skin

1 Introduction on Natural Patterns

2 Patterning of the Vertebrate Skin

3 Future Directions

Chapter 16 Nuclear Transfer for Cloning Animals

1 Introduction and Brief Historical Overview

2 Key Elements and Critical Aspects of NT Technology

3 Applications of NT in Different Species

4 Future Perspectives of NT

Chapter 17 Regulation in the Early \textit{Drosophila} Embryo

1 The Basics of Embryogenesis

2 A-P Patterning: Segmentation and Segment Identity

3 D-V Patterning: Specification of Mesoderm, Neuroectoderm, and Ectoderm

4 Formation of a Maternal Gradient: Sizing Up the Embryo

5 Zygotic Genome Activation: Coordination of Gene Expression in Space and Time

6 Gene Regulatory Networks: Guiding the Trajectories of Cell Fate Determination

7 \textit{cis}-Regulatory Modules: Integration of Transcriptional Inputs during Pattern Formation

8 Conclusions and Future Perspectives

Part V Organogenesis

Chapter 18 Growing Mini-Organs from Stem Cells

2 Spatiotemporal Control of Mini-Organ Structure and Differentiation.

3 Organoid Technology

4 Missing Cues in Current Organoid Technology

5 Organ Bud Technology

6 The Future of Mini-Organ Technologies

Index

EULA.

Notes:

Description based on print version record.

Description based on publisher supplied metadata and other sources.

ISBN:

3-527-68589-8

OCLC:

1090984938