Introducing proteomics : from concepts to sample separation, mass spectrometry and data analysis / Josip Lovrić.

Format:

Book

Author/Creator:

Lovric, Josip, author.

Language:

English

Subjects (All):

Proteomics.

Physical Description:

1 online resource (297 p.)

Place of Publication:

Chichester, England : Wiley Blackwell, 2011.

Language Note:

English

Summary:

Introducing Proteomics gives a concise and coherent overview of every aspect of current proteomics technology, which is a rapidly developing field that is having a major impact within the life and medical sciences. This student-friendly book, based on a successful course developed by the author, provides its readers with sufficient theoretical background to be able to plan, prepare, and analyze a proteomics study. The text covers the following:Separation TechnologiesAnalysis of Peptides/Proteins by Mass SpectrometryStrategies in Proteomics This contemporary te

Contents:

Introducing Proteomics; Contents; Preface; Acknowledgements; 1 Introduction; 1.1 What Are the Tasks in Proteomics?; 1.2 Challenges in Proteomics; 1.3 Proteomics in Relation to Other-omics and System Biology; 1.4 Some General Applications of Proteomics; 1.5 Structure of the Book; References; 2 Separation and Detection Technologies; 2.1 Introduction to Experimental Strategies in Proteomics; 2.2 Gel-Based Separation; 2.3 Visualization and Analysis of Proteins/Peptides in Gels; 2.4 Gel-Free Separation Technologies; 2.5 Visualization of Proteins/Peptides from Hyphenated Methods

2.6 Chips in Proteomic ApplicationsReferences; 3 Analysis of Peptides/Proteins by Mass Spectrometry; 3.1 Basic Principles of Mass Spectrometry for Proteomics; 3.2 Ionization Methods for Small Amounts of Biomolecules; 3.3 Mass Analyzers and Mass Spectrometers; 3.4 Concluding Remarks on Mass Analyzers for Proteomics; References; 4 Analysis and Interpretation of Mass Spectrometric and Proteomic Data; 4.1 Introduction; 4.2 Analysis of MS Data; 4.3 Analysis of MS/MS Data; 4.4 Quantification of LC MS and MS/MS Data from Complex Samples

4.5 Bioinformatic Approaches for Mass Spectrometric Proteome Data AnalysisReferences; 5 Strategies in Proteomics; 5.1 Imaging Mass Spectrometry; 5.2 Qualitative Proteomics; 5.3 Differential and Quantitative Proteomics; 5.4 Analysis of Posttranslational Modifications; 5.5 Interaction Proteomics; 5.6 Proteomics as Part of Integrated Approaches; References; Index

Notes:

Description based upon print version of record.

Includes bibliographical references at the end of each chapters and index.

Description based on print version record.

ISBN:

9786613371744

9781119957195

1119957192

9781283371742

128337174X

9780470670217

0470670215

OCLC:

769263134