Catalysis for fine chemicals / Werner Bonrath, Jonathan Medlock, Marc-André Müller, Jan Schütz.

Format:

Book

Contributor:

Rosengarten Family Fund.

Series:

De Gruyter STEM

Language:

English

Subjects (All):

Catalysis.

Chemical processes.

Medical Subjects:

Catalysis.

Physical Description:

xi, 392 pages : illustrations (black and white, and colour) ; 24 cm

Place of Publication:

Berlin ; Boston : De Gruyter, [2021]

Contents:

1 Introduction and fundamental aspects p. 1

1.1 General concepts of catalysis p. 3

1.1.1 Basics of thermodynamics and kinetics for chemical reactions p. 3

1.1.2 General principles of heterogeneous catalysis p. 9

1.1.3 Mechanisms and kinetics on catalyst surfaces p. 11

1.1.4 Characterisation of solid catalysts p. 15

1.2 Catalyst preparation p. 28

1.3 Chemical reactors for catalytic processes p. 30

2 Heterogeneous hydrogenations p. 37

2.2 Nickel catalysts p. 43

2.2.1 Hydrogenation of nitrites p. 43

2.2.2 Hydrogenation of carbonyl groups p. 50

2.2.3 Hydrogenation of other functional groups p. 51

2.2.4 Reduction of multiple functional groups in the same reaction p. 54

2.3 Platinum Group Metal (PGM) based catalysts p. 55

2.3.1 Palladium catalysts p. 58

2.3.2 Platinum catalysts p. 78

2.3.3 Other PGM catalysts p. 83

2.4 Other metal catalysts p. 85

3 Homogeneous hydrogenations p. 91

3.2 Rh-catalysed hydrogenations p. 92

3.2.1 (S)-3-(3,4-dihydroxyphenyl)alanine, L-DOPA p. 92

3.2.2 Menthol (BASF Process) p. 99

3.2.3 Methylene succinamic acid p. 102

3.2.4 Aliskiren p. 103

3.2.5 Pregabalin p. 107

3.2.6 (+)-Biotin p. 107

3.2.7 Sitagliptin p. 109

3.2.8 Pantolactone p. 111

3.3 Ru-catalysed hydrogenations p. 112

3.3.1 Hydrogenation of allylic alcohols p. 112

3.3.2 Pivotal glutarate intermediate for candoxatril p. 114

3.3.3 Artemisinin p. 115

3.3.4 Ketone reductions p. 116

3.3.5 Dynamic kinetic resolution via asymmetric hydrogenation p. 119

3.4 Ir-catalysed hydrogenation p. 121

3.4.1 Hydrogenation of imines p. 121

3.4.2 Hydrogenation of ketones with iridium catalysts p. 124

3.4.3 Hydrogenation of unfunctionalised doubled bonds p. 125

3.5 Asymmetric transfer hydrogenation of C=O and C=N p. 128

3.5.1 Dorzolamide p. 130

3.5.2 Styrene oxide p. 131

3.5.3 (R,R)-trans-Actinol for zeaxanthin p. 131

3.5.4 Almorexant p. 132

4 Oxidations p. 142

4.2 Oxidation of alcohols p. 143

4.3 Oxidation of phenols and aromatic compounds p. 144

4.4 Oxidation of various C-C bonds p. 150

4.5 Oxidation for silane production p. 162

5 Gas-phase reactions p. 170

6 C-C-bond and C-N-bond forming reactions (metal-catalysed) p. 184

6.1 Introduction and Mizoroki-Heck reactions p. 184

6.2 Other palladium catalysed C-C bond forming reactions p. 189

6.2.1 Sonogashira-Hagihara reaction p. 189

6.2.2 Suzuki-Miyaura-coupling p. 192

6.2.3 Kumada-Corriu coupling p. 198

6.3 Carbonylation reactions p. 199

6.4 Hydroformylation reactions p. 201

6.5 SHOP process p. 205

6.6 1,3-Diene functionalisation p. 207

6.7 Telomerisation p. 208

6.8 Metathesis p. 217

6.9 Formation of C-N bonds (Buchwald-Hartwig coupling) p. 222

7 Rearrangement reactions p. 235

7.2 Wagner-Meerwein rearrangements p. 235

7.3 Beckmann rearrangement p. 237

7.4 [3,3]-Sigmatropic-type rearrangements p. 237

7.5 The Meyer-Schuster, Rupe-Kambli and Pauling rearrangements p. 246

7.6 Allylic rearrangements p. 249

8 Acid-base-catalysed reactions p. 257

8.1 Replacement of Brønsted acids p. 257

8.2 Zeolite-based catalysis p. 263

8.3 Heteropoly acids (HPAs) p. 267

8.4 Lewis acids p. 273

8.5 Base catalysis p. 280

8.6 Ethynylation p. 286

8.7 Mannich reactions p. 288

9 Phase transfer catalysis (PTC) p. 296

10 Biocatalysis p. 311

10.1 Introduction to biocatalysis p. 311

10.2 Industrial applications p. 322

10.2.1 Sauerkraut and ethanol: applications with a long history p. 322

10.2.2 Sugars and oligosaccharides p. 325

10.2.3 Organic acids p. 329

10.2.4 Amino acids p. 335

10.2.5 Vitamins and carotenoids p. 341

10.2.6 Active pharmaceutical ingredients p. 353

10.2.7 Flavour compounds p. 363

10.2.8 Pesticides p. 365

10.2.9 Platform chemicals p. 366

11 New trends p. 378.

Notes:

Includes bibliographical references and index.

Local Notes:

Acquired for the Penn Libraries with assistance from the Rosengarten Family Fund.

Other Format:

Ebook version :

ISBN:

9783110571158

3110571153

OCLC:

1182512722

Publisher Number:

99990839970