Ion Mobility-Mass Spectrometry : Fundamentals and Applications / edited by Alison E. Ashcroft and Frank Sobott.

Format:

Book

Contributor:

Ashcroft, Alison E., editor.

Sobott, Frank, editor.

Series:

ISSO (Series)

Issn Series

Language:

English

Subjects (All):

Ion mobility spectroscopy.

Physical Description:

1 online resource (590 pages) : illustrations (chiefly colour)

Edition:

First edition.

Place of Publication:

London, England : The Royal Society of Chemistry, [2022]

Summary:

"Over the last decade, the use of ion mobility separation in combination with mass spectrometry analysis has developed significantly. This technique adds a unique extra dimension enabling the in-depth analysis of a wide range of complex samples in the areas of the chemical and biological sciences. Providing a comprehensive guide to the technique, each chapter is written by an internationally recognised expert and with numerous different commercial platforms to choose from, this book will help the end users understand the practicalities of using different instruments for different ion mobility purposes. The first section provides a detailed account of the fundamentals behind the technique and the current range of available instrumentation. The second section focusses on the wide range of applications that have benefitted from ion mobility – mass spectrometry and includes topics taken from current research in the pharmaceutical, metabolomics, glycomics, and structural molecular biology fields. The book is primarily aimed at researchers, appealing to practising chemists and biochemists, as well as those in the pharmaceutical and medical fields."--Provided by publisher.

Contents:

Ion mobility-mass spectrometry: an overview / Valérie Gabelica

Calculation of momentum transfer cross-sections / C. Bleiholder, F.C. Liu and M. Chai

Fundamentals of uniform-field drift tube ion mobility and collision cross section / S. M. Stow and J. C. Fjeldsted

Travelling wave ion mobility separation: basics and calibration / K. Richardson and K. Giles

Trapped ion mobility spectrometry: basics and calibration / M. Ridgeway, L. Woods and M. Park

Field asymmetric ion mobility spectrometry (FAIMS) for advanced mass spectrometry / M. Belford, S. Prasad, S. Peterman, E. Bonneil, J. Lanoix, C. Durette, P. Thibault, K. Motamedchaboki, R. Huguet, D. Lopez-Ferrer, R. D. Melani, K. Srzentić, L. Fornelli, N. L. Kelleher, R. W. Purves, K. Walker, Y. Zhu, G. de Albuquerque Cavalcanti, N. Wijeratne and C. Boeser

Computational approaches for processing native ion mobility-mass spectrometry data / T. Cragnolini and K. Thalassinos

CCS for modeling 3D structures / E. G. Marklund, M. T. Degiacomi, A. Politis and M. Landreh

Ion spectroscopy coupled to ion mobility-mass spectrometry / Iuliia Stroganova and Anouk M. Rijs

Ion mobility-mass spectrometry of pharmaceuticals / Andrew D. Ray, Anthony W. T. Bristow and Stephen W. Holman

Ion mobility spectrometry in mass spectrometry imaging / Oliver J. Hale, Eva Illes-Toth, Emma K. Sisley and Helen J. Cooper

Ion mobility-mass spectrometry in metabolomics studies / Emanuel Zlibut, Katrina L. Leaptrot, Jody C. May and John A. McLean

The role of ion mobility for antibody characterisation: a biopharmaceutical perspective / Iain D. G. Campuzano

Insights into membrane protein structure and function by means of ion mobility-mass spectrometry / Anna J. Higgins and Antonio N. Calabrese

Conformational characterisation of biomolecules / Ruth Knox, Alexey Barkhanskiy, Aidan P. France and Perdita E. Barran

Advanced IM-MS-based approaches for protein analysis: collision-induced unfolding (CIU) and hypenation of liquid chromatography to IM-MS / E. Deslignière, O. Hernandez-Alba and S. Cianférani

Ion mobility-mass spectrometry of nucleic acids / Dan Fabris

Glycomics and ion mobility / W. B. Struwe.

Notes:

Description based on publisher supplied metadata and other sources.

Description based on print version record.

Includes bibliographical references.

ISBN:

9781839162886

1839162880

9781839162893

1839162899

OCLC:

1286899134