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Animal Models of Human Birth Defects / edited by Aimin Liu.

LIBRA Per. v.1 (1967)-v.111 (1979) v.112 (1980)-v.267 (1990), v.269 (1990)-v.330 (1993), v.332 (1993)-v.363 (1995), v.365 (1994)-v.367 (1995), v.369 (1995)-v.370 (1994), v.371B (1995), v.372 (1995)-v.373 (1995), v.375 (1995)-v.401 (1996), v.403 (1996), v.406 (1997), v.408 (1997)-v.482 (2000)-v.483 (2000)
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Format:
Book
Contributor:
Liu, Aimin, Editor.
Series:
Advances in Experimental Medicine and Biology, 0065-2598 ; 1236
Language:
English
Subjects (All):
Diagnosis, Laboratory.
Animal models in research.
Molecular biology.
Laboratory Medicine.
Animal Models.
Molecular Medicine.
Local Subjects:
Laboratory Medicine.
Animal Models.
Molecular Medicine.
Physical Description:
1 online resource (vii, 244 pages) : illustrations.
Edition:
1st ed. 2020.
Place of Publication:
Singapore : Springer Singapore : Imprint: Springer, 2020.
Summary:
This book focuses on the use of animal models to study various human defects. It summarizes our current understanding of a variety of common human birth defects and the essential role of animal models in shedding light on the underlying mechanisms of these disorders. Birth defects are the leading cause of infant deaths, and cost billions of dollars in care for those affected. Unfortunately, the lack of a clear understanding of the mechanisms leading to many of these developmental disorders has hindered effective prevention and early intervention strategies. Studies using animal models have provided essential insights into several human birth defects. This book serves as a valuable reference resource for researchers and graduate students who are interested in learning the basic principles as well as the latest advances in the study of the mechanisms of human birth defects.
Contents:
Chapter 1: Using forward and reverse genetics in mouse to study birth defects
Chapter 2: Using animals to study neural tube defects
Chapter 3: Using animals to study ciliopathies
Chapter 4: Using animals to model human skeletal defects
Chapter 5: Understanding eye defects using animal models
Chapter 6: Modelling kidney and urinary tract defects in animals
Chapter 7: Pancreas development and type I diabetes
Chapter 8: Using animals to study human birth defects affecting the functions of the digestive system
Chapter 9: Modelling human birth defects with zebrafish
Chapter 10: Modelling diseases with C. elegans
Chapter 11: Infectious disease and birth defects.
ISBN:
981-15-2389-4

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