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B Cells in Immunity and Tolerance / edited by Ji-Yang Wang.

LIBRA Per. v.1 (1967)-v.111 (1979) v.112 (1980)-v.267 (1990), v.269 (1990)-v.330 (1993), v.332 (1993)-v.363 (1995), v.365 (1994)-v.367 (1995), v.369 (1995)-v.370 (1994), v.371B (1995), v.372 (1995)-v.373 (1995), v.375 (1995)-v.401 (1996), v.403 (1996), v.406 (1997), v.408 (1997)-v.482 (2000)-v.483 (2000)
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Format:
Book
Contributor:
Wang, Ji-Yang, Editor.
Series:
Advances in Experimental Medicine and Biology, 0065-2598 ; 1254
Language:
English
Subjects (All):
Immunology.
Molecular biology.
Allergy.
Molecular Medicine.
Allergology.
Local Subjects:
Immunology.
Molecular Medicine.
Allergology.
Physical Description:
1 online resource (190 pages).
Edition:
1st ed. 2020.
Place of Publication:
Singapore : Springer Singapore : Imprint: Springer, 2020.
Summary:
This book contains twelve chapters contributed by prestigious international experts who are at the forefront of B cell research, and aims to provide a cutting-edge and comprehensive overview of all aspects of B cells, including B cell development, maturation and activation, germinal center reaction, memory and plasma cell differentiation, and antibody-mediated positive and negative regulation of humoral immune responses. There are also three chapters describing human diseases caused by B cell abnormalities, including primary antibody deficiencies, autoimmune diseases, and B cell malignancies. We hope that this book will become a standard and routine reference for both basic researchers and clinicians.
Contents:
B cell development and maturation
B cell receptor signalling
Involvement of reactive oxygen species (ROS) in BCR signaling as a second messenger
Germinal center reaction
Memory B cells in local and systemic sites
Regulation of plasma cell differentiation
Regulation of humoral immune responses and B cell tolerance by the IgM Fc receptor
Regulatory B cells
Diversified IgA-bacteria interaction in gut homeostasis
Primary antibody deficiencies
B cell-mediated autoimmune diseases
B cell lymphomas.
ISBN:
981-15-3532-9

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