Comprehensive biomaterials II. Volume 1, Metallic, ceramics, and polymeric biomaterials / Paul Ducheyne [and three others], editors.

Format:

Book

Contributor:

Ducheyne, Paul, editor.

Language:

English

Subjects (All):

Biomedical materials.

Physical Description:

1 online resource (4,684 pages) : illustrations

Edition:

2nd ed.

Place of Publication:

Amsterdam, Netherlands : Elsevier, 2017.

Summary:

Comprehensive Biomaterials II, Second Edition, Seven Volume Set brings together the myriad facets of biomaterials into one expertly-written series of edited volumes. Articles address the current status of nearly all biomaterials in the field, their strengths and weaknesses, their future prospects, appropriate analytical methods and testing, device applications and performance, emerging candidate materials as competitors and disruptive technologies, research and development, regulatory management, commercial aspects, and applications, including medical applications.Detailed coverage is given to both new and emerging areas and the latest research in more traditional areas of the field. Particular attention is given to those areas in which major recent developments have taken place. This new edition, with 75% new or updated articles, will provide biomedical scientists in industry, government, academia, and research organizations with an accurate perspective on the field in a manner that is both accessible and thorough.- Reviews the current status of nearly all biomaterials in the field by analyzing their strengths and weaknesses, performance, and future prospects- Covers all significant emerging technologies in areas such as 3D printing of tissues, organs and scaffolds, cell encapsulation; multimodal delivery, cancer/vaccine - biomaterial applications, neural interface understanding, materials used for in situ imaging, and infection prevention and treatment- Effectively describes the many modern aspects of biomaterials from basic science, to clinical applications

Contents:

e9780081006917v1_WEB.pdf

Cover

COMPREHENSIVE BIOMATERIALS II

CONTENTS OFVOLUME1

EDITOR BIOGRAPHIES

Editor in Chief

Co-Editors

CONTRIBUTORS TOVOLUME1

CONTENTS OFALLVOLUMES

PREFACE OFTHEFIRSTEDITION

PREFACE

FOREWORD OFTHEFIRSTEDITION

FOREWORD

BIOMATERIALS

1.1 Metals for Use in Medicine

Glossary

1.1.1 Introduction

1.1.2 General Requirements for Long-Term Implantation

1.1.3 Key Metallurgy Concepts

1.1.4 Chemical Composition and Structure

1.1.4.1 Stainless Steels

1.1.4.2 Cobalt Base Alloys

1.1.4.3 Titanium Base Alloys

1.1.4.4 Other Implantable Metals

1.1.5 Mechanical Properties

1.1.5.1 Static Properties

1.1.5.2 Fatigue

1.1.6 Processing Effects

1.1.6.1 Metal Processing Overview

1.1.6.2 Process Effect Examples

1.1.6.2.1 Work hardening and annealing

1.1.6.2.2 Wrought versus cast alloys

1.1.6.2.3 Precipitation hardening

1.1.6.2.4 Surface condition effects

1.1.7 Future Developments

1.1.8 Summary

See also

References

1.2 Electrochemical Behavior of Metals in the Biological Milieu

1.2.1 Introduction

1.2.2 Metals Currently Used in Medical Devices

1.2.2.1 Titanium Alloys

1.2.2.2 Co-Cr-Mo Alloys

1.2.2.3 Stainless Steel

1.2.3 Metallic Biocompatibility

1.2.3.1 Immune Response and Haptens

1.2.3.2 Wound Healing and Biocompatibility

1.2.3.3 The Reduction Half-Cell in Biomaterials Corrosion

1.2.4 The Biological Milieu

1.2.4.1 The In Vitro Approximation to the Biological Milieu

1.2.5 Basic Electrochemistry Concepts

1.2.5.1 Active Corrosion Theory: Oxidation and Reduction

1.2.5.2 Passivating Metal Surface Behavior

1.2.5.3 Polarization Testing

1.2.5.3.1 Linear polarization and Rp

1.2.5.3.2 Cyclic and anodic polarization testing.

1.2.6 Passive Oxide Films and Semiconducting Electrochemistry

1.2.6.1 Introduction to Passive Oxide Films

1.2.6.2 High Electric Field Oxide Growth

1.2.6.3 Redox Electrochemistry at Oxide-Solution and Oxide-Metal Interfaces

1.2.6.4 Oxide Semiconductor Theory for Thin Oxide Films Between Metals and Solutions

1.2.7 Electrical Double Layer

1.2.8 Electrochemical Impedance Spectroscopy (EIS) of Metallic Biomaterials

1.2.8.1 The Methods of EIS

1.2.8.2 Time-Based Methods

1.2.8.3 Impedance Behavior of Ti, CoCr, and 316L SS: Effects of Solution, Voltage, and Time

1.2.9 Mechanically Assisted Corrosion

1.2.9.1 Modeling the Electrochemical Response to Scratching

1.2.9.2 The Consequences of Mechanically Assisted Corrosion In Vivo

1.2.10 Effects of Prior Electrochemical History

1.2.11 Oxide Film Structure and Formation

1.2.12 Effects of Solution Redox System

1.2.13 Biological Consequences: Oxidation and Reduction

1.2.14 Summary

1.2.15 Appendix: Derivation of Mott-Schottky Equation

Acknowledgments

1.3 Shape Memory Alloys for Use in Medicine

1.3.1 Introduction

1.3.2 Fundamentals of Shape Memory Systems

1.3.3 Practical Shape Memory Alloys

1.3.4 Manufacturing, Processing and Performance of Nitinol

1.3.4.1 Melting Methods and Compositional Effects

1.3.4.2 Production of Semi-Finished Wrought Products

1.3.4.3 Heat Treatment to Control Performance

1.3.4.4 Characterization Methods and Some Basic Material Properties

1.3.4.4.1 Transformation temperatures

1.3.4.4.2 Tensile behavior

1.3.5 Minimally Invasive Device Applications for Nitinol

1.3.5.1 Cardiovascular Stents

1.3.5.1.1 Deployment considerations

1.3.5.1.2 Manufacturing methods

1.3.5.1.3 Cardiovascular stents - Clinical examples

1.3.5.2 Other Cardiovascular Devices.

1.3.5.3 Non-Vascular Stents

1.3.6 Orthodontic Applications for Nitinol

1.3.7 Orthopedic Applications for Nitinol

1.3.8 Clinical Imaging of Nitinol Medical Devices

1.3.9 Long Term Durability and Biocompatibility of Nitinol

1.3.9.1 Fatigue Behavior of Nitinol

1.3.9.2 Corrosion Behavior of Nitinol

1.3.9.3 Biocompatibility Aspects of Nitinol

1.3.10 Summary and Future Directions

1.4 Silver Antimicrobial Biomaterials

1.4.1 Introduction

1.4.1.1 History

1.4.1.2 Mechanism of Antibacterial Activity for Metallic Silver

1.4.1.3 Mechanism of Antibacterial Activity for Agplus

1.4.2 Silver Nanomaterials

1.4.2.1 Silver Presence in Nanomaterial Products

1.4.2.2 Proposed Mechanism of Antimicrobial Activity for Silver Nanomaterials

1.4.3 Silver Resistance

1.4.4 Implanted Silver Biomaterial Clinical Products

1.4.4.1 Clinical Efficacy of Silver Biomaterial Products

1.4.5 Toxicity of Silver Formulations

1.4.5.1 Effect of Oral Silver Formulations on the Microbiome

1.4.6 Conclusions and Outlook

1.5 Alumina

1.5.1 Introduction

1.5.2 Properties of Alumina

1.5.2.1 Physical Properties

1.5.2.2 Mechanical Properties

1.5.2.3 Stability in Wet Environment

1.5.2.4 Wear Behavior of Alumina

1.5.2.4.1 Simulator tests on alumina-on-PE bearings

1.5.2.4.2 Simulator tests on alumina-on-alumina bearings

1.5.2.4.3 Microseparation tests on alumina-on-alumina bearings

1.5.2.5 Biocompatibility

1.5.2.5.1 In vitro tests

1.5.2.5.2 In vivo tests

1.5.2.5.3 Carcinogenicity

1.5.2.6 Reaction to Ceramic Wear Debris

1.5.3 Clinical Application of Alumina Ceramics

1.5.3.1 Technology of Ceramics for THR Bearings

1.5.3.2 Design of Ceramic THR Bearings

1.5.3.3 Clinical Results

1.5.3.4 Complications

1.5.3.4.1 Failures in THR bearings.

1.5.3.4.2 Noises in THR bearings

1.5.3.5 Tips and Tricks in Alumina Bearings

1.5.3.6 Revision Strategies

1.5.3.7 Alumina in Knee Replacements

1.5.3.8 Alumina in Other Medical Devices

1.6 Zirconia as a Biomaterial

1.6.1 Introduction

1.6.1.1 The Discovery of Phase Transformation in the 70's: A Revolution in the Ceramic Field

1.6.1.2 The Logical Development as a Structural Bio-Ceramic

1.6.1.3 Phase Transformation and Aging: The Two Sides of Zirconia

1.6.2 Crystallography and Phase Transformation of Zirconia

1.6.2.1 Crystallography and Phases Stability

1.6.2.2 Stress Induced Phase Transformation and Toughening

1.6.2.3 Surface Transformation in the Presence of Water and Low Temperature Degradation

1.6.3 Different Types of Zirconia and Zirconia Based Composites

1.6.3.1 Alloy Additives for Zirconia

1.6.3.2 Partially Stabilized Zirconia Ceramics

1.6.3.3 Tetragonal Zirconia Polycrystals

1.6.3.4 Zirconia Dispersed Ceramics

1.6.4 The Use of Zirconia as a Biomaterial: Current State of the Art

1.6.4.1 The Use of Zirconia in Orthopedics: From Yttria-Doped Zirconia to Zirconia Toughened Alumina

1.6.4.2 The Use of Zirconia in the Dental Field: From Dental Restoration to Implants

1.6.4.3 On the Assessment of Aging: Some Useful Tools

1.6.5 Future Directions

1.6.5.1 Tough, Strong and Stable Zirconia Ceramics and Composites: The Necessary Challenge

1.6.5.2 Taking Advantage of the Materials Towards New Design of Implants

1.6.5.3 New Processes

1.6.5.3.1 Additive manufacturing

1.6.5.3.2 Gradient materials

1.6.5.3.3 Surface modifications

1.6.6 Conclusion

1.6.6.1 Further Reading

Relevant Website

1.7 Carbon and Diamond

1.7.1 Introduction

1.7.2 Pyrolytic Carbon

1.7.2.1 Introduction.

1.7.2.2 Production of Pyrolytic Carbon

1.7.2.2.1 Fluidized-bed production of pyrolytic carbon

1.7.2.2.2 Tumbling and stationary bed production of pyrolytic carbon

1.7.2.3 Mechanical Properties of Pyrolytic Carbon

1.7.2.4 Biological Properties and Biomedical Applications of Pyrolytic Carbon

1.7.2.4.1 Cardiovascular applications of pyrolytic carbon

1.7.2.4.2 Orthopedic applications of pyrolytic carbon

1.7.2.4.3 Shortcomings of pyrolytic carbon

1.7.3 Diamond-Like Carbon

1.7.3.1 Introduction to DLC

1.7.3.2 Production and Characterization of DLC

1.7.3.2.1 Raman spectroscopic characterization of DLC

1.7.3.2.2 Nuclear magnetic resonance and electron energy loss spectroscopy of DLC

1.7.3.3 Properties of DLC

1.7.3.3.1 Electronic properties of DLC

1.7.3.3.2 Mechanical properties of DLC

1.7.3.4 Applications and Biological Properties of DLC

1.7.3.4.1 Orthopedic applications of DLC

1.7.3.4.2 Cardiovascular applications of DLC

1.7.3.4.3 Additional applications of DLC

1.7.4 Microcrystalline, Nanocrystalline, and Ultrananocrystalline Diamond

1.7.4.1 Introduction to MCD, NCD, and UNCD

1.7.4.2 Production of MCD, NCD, and UNCD

1.7.4.2.1 CVD and film growth

1.7.4.2.2 Hot-filament CVD of diamond films

1.7.4.2.3 Microwave PECVD of diamond films

1.7.4.2.4 Additional diamond film production methods

1.7.4.3 Mechanical and Biological Properties of MCD, NCD, and UNCD

1.7.4.4 Biomedical Applications of MCD, NCD, and UNCD

1.7.4.4.1 Biosensor applications

1.7.4.4.2 Orthopedic applications

1.7.4.4.3 Further biomedical applications

1.7.5 Summary of Carbon and Diamond

1.8 Wear-Resistant Ceramic Films and Coatings

1.8.1 Introduction.

1.8.2 State of the Art - Processing, Microstructure, Biocompatibility and Mechanical Properties of Ceramic Coatings.

Notes:

Includes bibliographical references.

Description based on online resource; title from PDF title page (ebrary, viewed July 6, 2017).

ISBN:

0-08-100692-6