Cancer metastasis and cancer stem cell/niche / edited by Takanori Kawaguchi & Department of Pathology General Aizu Chuo Hospital.

Format:

Book

Author/Creator:

Kawaguchi, Takanori, Author.

Contributor:

Kawaguchi, Takanori, editor.

Department of Pathology General Aizu Chuo Hospital, editor.

Language:

English

Subjects (All):

Metastasis.

Physical Description:

1 online resource (157 pages) : illustrations, tables

Place of Publication:

Sharjah, United Arab Emirates : Bentham Books, 2016.

Summary:

A malignant tumor is an actively growing tissue composed of cells derived from a single cell line that has undergone irreversible differentiation. These cells are invasive and also metastasize in the body resulting in malignant cancer. Recent research suggests that a malignant tumor originates from cancer stem cells (CSC) accompanied with physiological niches. Cancer Metastasis and Stem Cell/Niche explains the invasiveness and metastasis of cancer cells I the light of information gained from the CSC / niche theory. Five chapters present a review on the fundamental relationships between CSCs their niche and metastasis the regulation of cell surface glycan expression in CSCs tumor endothelial cells and metastasis toll-like receptor 4 (TLR4)-mediated premetastatic microenvironment and in surgical cancer metastasis. This monograph is intended as a primary reference on CSC research for physiologists clinical oncologists stem cell researchers and molecular biologists.

Contents:

Cancer Metastasis and Cancer Stem Cell/Niche

Notes:

Includes bibliographical references at the end of each chapters and index.

Description based on online resource; title from PDF title page (Ebrary, viewed December 23, 2016).

ISBN:

9781681083476

1681083477

OCLC:

1511479790