The illusion of evidence-based medicine : exposing the crisis of credibility in clinical research / Jon Jureidini and Leemon B. McHenry.

Format:

Book

Author/Creator:

Jureidini, Jon, author.

McHenry, Leemon B., 1950- author.

Language:

English

Subjects (All):

Evidence-based medicine.

Clinical medicine.

Pharmaceutical industry.

Physical Description:

1 online resource (329 pages) : illustrations.

Place of Publication:

Mile End, South Australia : Wakefield Press, [2020]

Summary:

An expose of the corruption of medicine by the pharmaceutical industry at every level, from exploiting the vulnerable destitute for drug testing, through manipulation of research data, to disease mongering and promoting drugs that do more harm than good. This is a brilliant expose of the negative influence of the global pharmaceutical industry.

Contents:

About the authors

Title page

Imprint

Dedication

Contents page 1

Contents page 2

Preface

Chapter 1 - The Crisis of Credibility in Clinical Research

Case Studies in Industry Malfeasance

The Privatization of Knowledge and Conflicts of Interest

Chapter 2 - The Corruption of Clinical Research: Study 329 and Study CIT-MD-18

Misreporting of Industry-Corrupted Psychiatric Trials

Ghostwriting of the Manuscripts

The Marketing Strategy

Concerns in the Public Domain

Role of the Journals

Successful Efforts to Block Publication of Critical Evaluations

Conclusion

Chapter 3 - A Rigorous Conception of Science in Medicine

Popper's Critical Rationalism

Industry Science

Limitations of Popper's Approach

The Science of Clinical Trials

Evidence-Based Medicine

Chapter 4 - Communication of Scientific Findings

Medical Communications and Public Relations

Publication Planning

Ghost and Honorary Authors

The Harms of Ghostwriting to Academe and Patients

Industry Response: Poisoning the Well

Continuing Medical Education and Medical Conferences

Clinical Practice Guidelines

Chapter 5 - Academics and the Corporate University

Commercialization of the Academy

Key Opinion Leaders as Product Champions

Academic Medical Centers' Policies

Academic Freedom in Medicine

Chapter 6 - Distorted Research Priorities

Ignoring Essential Medicines

Exploiting Psychiatry's Dubious Nosology for Disease Mongering

Mental Health Screening and its Contribution to Disease Mongering

Chapter 7 - Regulators and Governance

Failures of Regulation

Drug Companies as Clients of Regulators

Betrayal of Research Participants

Chapter 8 - Solutions

Minimally Effective Responses

A Radical Proposal.

Notes:

Includes bibliographical references (pages 279-302) and index.

ISBN:

1-74305-749-0