New approaches to the aortic disease from valve to abdominal bifurcation / edited by Ion C. Ţintoiu [and four others].

Format:

Book

Contributor:

Ţintoiu, Ion C., editor.

Language:

English

Subjects (All):

Aorta--Diseases.

Aorta.

Aorta--Diseases--Diagnosis.

Cardiovascular system--Diseases--Treatment.

Cardiovascular system.

Physical Description:

1 online resource (626 pages) : illustrations (some color), tables

Edition:

1st ed.

Place of Publication:

London, England : Academic Press, 2018.

Summary:

New Approaches to Aortic Disease from Valve to Abdominal Bifurcation provides a complete look at aortic valve diseases from all points of view, including etiology, physiopathology, prevention, diagnosis and treatment. The book offers new insights into the aortic valve and pathology based on evidence of current diagnostic methods, treatments and post-surgery evolution. Content is split into three distinct parts for ease of reference, including an overview of aortic pathology, diagnostic evaluations methods, and treatments. Also included are guidelines and future research directions, making this a must-have volume for all cardiologists and cardiovascular surgeons who address significant issues in this topic area.- Present pathophysiological sequences that are shown in correlation with histological details- Includes detailed clinical examinations and the value of the initial assessment using chest X-ray, echocardiography, angiography, CT angiography and magnetic resonance, etc.- Provides conventional descriptions of surgical techniques that are entirely detailed, along with long-term results and possible complications

Contents:

Front Cover

New Approaches to Aortic Diseases from Valve to Abdominal Bifurcation

Dedication

Copyright

Contents

List of Contributors

Preface

1 - Overview

1 - Aging Aorta-Cellular Mechanisms

AGING AND STIFFNESS AORTA

INTIMA-ENDOTHELIAL SENESCENCE

INTIMA AND MEDIA-APOPTOSIS

INTIMA-EXTRACELLULAR MATRIX AND MMPS ROLES

MEDIA-VSMCS

MEDIA-ELASTIN/COLLAGEN RATIO

MEDIA INFLAMMATION

TELOMERE LENGTH-A BIOMARKER OF AORTA AGING

ATHEROGENESIS

CONCLUSIONS

REFERENCES

FURTHER READING

2 - Endothelial Dysfunction in Aortic Aneurysm

OVERVIEW

OXIDATIVE STRESS

GRAFT ENDOTHELIALIZATION

3 - Histology of Aortic Disease and Progression of Aortic Dissection From Acute to Chronic

INTRODUCTION

NORMAL HISTOLOGY OF THE AORTA

HISTOLOGY OF AORTIC ANEURYSM AND DISSECTION

HISTOLOGY OF THE TRANSITION FROM ACUTE TO CHRONIC DISSECTION

MACROSCOPIC CHANGES OF THE TRANSITION FROM ACUTE TO CHRONIC DISSECTION

Stanford Type B Dissections

Expansion of the Dissected Aorta

Progression of the Dissection

False Lumen Patency

Intimal Flap Architecture and Its Dynamics

Stanford Type A Dissection

4 - The Pathogenesis of Aortic Valvular Disease

PATHOGENESIS OF AORTIC STENOSIS

The Inflammatory Process

The Lipoprotein Anomalies

The Activation of Renin-Angiotensin System

Calcification in Aortic Stenosis

AORTIC REGURGITATION

5 - Aortic Root Pathologies

FUNCTIONAL ANATOMY

HISTOPATHOLOGIC CHANGES

AORTIC ROOT PATHOLOGIES

Aging

Aneurysm

Poststenotic Dilatation

Sinus of Valsalva Aneurysm With/Without Rupture

Pseudoaneurysm

Dilatation Associated With Congenital Heart Diseases.

Aortic Root Abscess

Aorto-Left Ventricular Tunnel

Porcelain Aorta

Supravalvular Stenosis

Aortic Dissection

6 - Cellular Mechanisms of Ascending Aortic Aneurysms

STRUCTURE, SIZE, AND LOCATION OF AORTA

DIAGNOSIS AND RISK FACTORS OF ASCENDING AORTIC ANEURYSM

CHARACTERIZATION OF ASCENDING AORTIC ANEURYSMS

CELLULAR MECHANISMS OF ASCENDING AORTIC ANEURYSM

Endothelial Cells

Smooth Muscle Cells

Fibroblasts

Immune Cells

Elastin

Collagen

Microfibrils and Fibrillin

Fibulin

ADDITIONAL FACTORS INVOLVED IN ASCENDING AORTIC ANEURYSM

POTENTIAL DRUG TREATMENTS FOR ASCENDING AORTIC ANEURYSM

SUMMARY

ACKNOWLEDGMENTS

7 - Mathematical Modeling of Aortic Aneurysm Progression

MATHEMATICAL MODELING AND SYSTEMS ANALYSIS OF BIOLOGICAL PHENOMENA

PETRI NET-BASED MODEL OF AORTIC ANEURYSM PROGRESSION

8 - Genetic Basis of Aortic Disease

SYNDROMIC THORACIC AORTIC ANEURYSMS AND DISSECTIONS

Marfan Syndrome

Genetic Basis and Molecular Mechanisms

Loeys-Dietz Syndrome

Ehlers-Danlos Syndromes

Arterial Tortuosity Syndrome

Cutis Laxa

Turner Syndrome

Noonan Syndrome

Shprintzen-Goldberg Syndrome

MASS Phenotype

NONSYNDROMIC THORACIC AORTIC ANEURYSMS AND DISSECTIONS

Familial TAAD

Bicuspid Aortic Valve With Thoracic Aortic Aneurysm

Persistent Patent Ductus Arteriosus With Thoracic Aortic Aneurysm

9 - Congenital Malformations (Bicuspid, Right Aortic Arch, Coarctation)

BICUSPID AORTIC VALVE AND ASSOCIATED AORTOPATHY

Newer Developments

RIGHT AORTIC ARCH.

Newer Developments

COARCTATION

CONCLUSION

ACKNOWLEDGMENT

10 - Guilt by Association: Paradigm for Detection of Silent Aortic Aneurysms

INTRACRANIAL ANEURYSM

AORTIC ARCH ANOMALIES

ABDOMINAL AORTIC ANEURYSM

BICUSPID AORTIC VALVE

A POSITIVE THUMB-PALM SIGN

FAMILY HISTORY OF AORTIC DISEASE

SIMPLE RENAL CYSTS

GIANT CELL ARTERITIS (AND OTHER AUTOIMMUNE DISORDERS)

Other Conditions-Ongoing Research

11 - Inflammatory Diseases (Takayasu, Giant Cell Arteritis, Behçet Disease)

VASCULAR INFLAMMATION-CENTRAL ROLE IN THE PATHOGENESIS OF TAKAYASU'S ARTERITIS, GIANT CELL ARTERITIS, AND BEHÇET DISEASE

BIOMARKERS IN INFLAMMATORY VASCULITIS

DIAGNOSTIC IMAGING AND ASSESSMENT OF AORTIC INFLAMMATION

PLEIOTROPIC THERAPY OF INFLAMMATORY VASCULITIS

Corticosteroids and Cytotoxic Agents

Future Therapies

B Cell Depletion

II - Diagnostic Evaluation Methods

12 - Chest X-Ray in Aortic Disease

CAPABILITIES OF THE PLAIN CHEST X-RAY

DIAGNOSIS OF ACUTE AORTIC SYNDROME

13 - Echocardiography in Aortic Valve Stenosis

DEGENERATIVE AORTIC STENOSIS

RHEUMATIC AORTIC STENOSIS

CONGENITAL AORTIC STENOSIS

QUANTIFICATION OF AORTIC STENOSIS

CALCULATING THE JET VELOCITY AND THE TRANSAORTIC PRESSURE GRADIENT

AORTIC VALVE AREA

SPECIAL VARIETIES OF VALVULAR AORTIC STENOSIS

LOW-FLOW, LOW-GRADIENT AORTIC STENOSIS WITH REDUCED LEFT VENTRICULAR EJECTION FRACTION

PARADOXICAL LOW-FLOW, LOW-GRADIENT AORTIC STENOSIS

AORTIC STENOSIS ASSOCIATED WITH A NONCOMPLIANT LEFT VENTRICLE, WITH REDUCED EJECTION FRACTION

AORTIC STENOSIS ASSOCIATED WITH SYSTOLIC AORTIC REGURGITATION

STRESS ECHOCARDIOGRAPHY IN ASYMPTOMATIC AORTIC STENOSIS

REFERENCES.

14 - Echocardiographic Assessment of the Aorta

ECHOGRAPHY FOR THE ASSESSMENT OF NORMAL THORACIC AORTA

Normal Anatomy and Dimensions of the Thoracic Aorta

Echocardiography for the Assessment of Thoracic Aorta

ECHOGRAPHY FOR THE ASSESSMENT OF PATHOLOGY OF THORACIC AORTA

Acute Aortic Syndrome

Chronic Aortic Conditions

Intraoperative and Postsurgical Echocardiographic Assessment

DUPLEX ULTRASOUND AND OTHER ECHOGRAPHIC TECHNIQUES FOR THE ASSESSMENT OF ABDOMINAL AORTA

Sonographic Anatomy

Scanning Technique by Duplex Ultrasound and Normal Appearance of Abdominal Aorta

Echographical Assessment of Abdominal Aorta Diseases

Abdominal Aortic Aneurysm

Abdominal Aortic Dissection

Abdominal Aortic Stenosis

Choice of the Imaging Modality

15 - Echocardiography in Acute Aortic Syndromes

ACUTE AORTIC SYNDROMES: CLASSIFICATION, CLINICAL MANIFESTATION, AND MANAGEMENT

Definition, Pathophysiology, and Classification

Epidemiology

Clinical Presentation and Prognosis

ROLE OF ECHOCARDIOGRAPHY IN DIAGNOSIS OF ACUTE AORTIC SYNDROME

Transthoracic Echocardiography

Transesophageal Echocardiography

Comprehensive Echocardiographic Management of Acute Aortic Syndrome

PERIOPERATIVE ECHOCARDIOGRAPHIC ASSESSMENT

16 - Transesophageal Echocardiography in the Assessment of Aortic Valve and Aortic Root Disease

TECHNICAL AND PRACTICAL CONSIDERATIONS

TRANSESOPHAGEAL ECHOCARDIOGRAPHY ROLE IN THE MORPHOLOGICAL ASSESSMENT OF AORTIC VALVE DISEASE

TRANSESOPHAGEAL ECHOCARDIOGRAPHY ROLE IN EVALUATION OF AORTIC STENOSIS

TRANSESOPHAGEAL ECHOCARDIOGRAPHY ROLE IN EVALUATION OF AORTIC REGURGITATION

TRANSESOPHAGEAL ECHOCARDIOGRAPHY ROLE IN THE MORPHOLOGICAL ASSESSMENT OF AORTIC ROOT DISEASE

17 - 3D Virtual Intravascular Endoscopy of Aortic Disease

VIRTUAL INTRAVASCULAR ENDOSCOPY

VIRTUAL INTRAVASCULAR ENDOSCOPY OF AORTIC ANEURYSM

VIRTUAL INTRAVASCULAR ENDOSCOPY OF AORTIC DISSECTION

VIRTUAL INTRAVASCULAR ENDOSCOPY OF ENDOVASCULAR STENT GRAFTS

18 - CT Angiography

CT ANGIOGRAPHY OF THE AORTA

CT Angiographic Technique

CT Protocols

Image Postprocessing

Radiation Dose Reduction Strategies

Normal Aortic Anatomy

ABNORMALITIES OF THE AORTA

Congenital Anomalies

Atherosclerosis

Aortoiliac Occlusive Disease

Aneurysms

Inflammatory Diseases

Aortic Fistulas

Aortic Masses

Preoperative and Postoperative Evaluation of the Aorta

19 - Magnetic Resonance Angiography

PATIENT PREPARATION, IMAGING TECHNIQUE, AND DATA POSTPROCESSING

NORMAL AORTA

AORTIC ANEURYSM

ACUTE AORTIC SYNDROMES

AORTITIS

AORTIC STENOSIS

AORTIC COARCTATION

FOLLOW-UP EXAMINATIONS

20 - CT and MRI in Acute Aortic Syndrome

CHOICE OF IMAGING MODALITY

COMPUTED TOMOGRAPHY ANGIOGRAPHY OF THE AORTA

MAGNETIC RESONANCE ANGIOGRAPHY OF THE AORTA

AORTIC DISSECTION

INTRAMURAL HEMATOMA

PENETRATING AORTIC ULCER

21 - Dual-Energy CT of Aortic Disease

PRINCIPLES OF DECT

DECT TECHNIQUES

IMAGE WEIGHTING FACTOR

VIRTUAL NONCONTRAST IMAGES

VIRTUAL MONOCHROMATIC IMAGING

ITERATIVE RECONSTRUCTION

CONTRAST MEDIUM DOSE

APPLICATIONS OF DECTA IN AORTIC DISEASE

Aortic Aneurysm

Endoleak Detection

RADIATION DOSE

III - Treatment

22 - Current Status of Medical Therapy of Thoracic Aortic Aneurysm and Dissection.

INTRODUCTION.

Notes:

Includes bibliographical references at the end of each chapters and index.

Description based on online resource; title from PDF title page (EBC, viewed December 15, 2017).

ISBN:

0-12-809980-1

0-12-809979-8