Selection of the HPLC method in chemical analysis / Serban Moldoveanu, Victor David.

Format:

Book

Author/Creator:

Moldoveanu, Șerban, author.

David, Víctor, author.

Language:

English

Subjects (All):

High performance liquid chromatography--Methodology.

High performance liquid chromatography.

Physical Description:

1 online resource (600 pages) : illustrations

Edition:

First edition.

Place of Publication:

Waltham, MA : Elsevier, [2017]

Summary:

Selection of the HPLC Method in Chemical Analysis serves as a practical guide to users of high-performance liquid chromatography and provides criteria for method selection, development, and validation.High-performance liquid chromatography (HPLC) is the most common analytical technique currently practiced in chemistry. However, the process of finding the appropriate information for a particular analytical project requires significant effort and pre-existent knowledge in the field. Further, sorting through the wealth of published data and literature takes both time and effort away from the critical aspects of HPLC method selection.For the first time, a systematic approach for sorting through the available information and reviewing critically the up-to-date progress in HPLC for selecting a specific analysis is available in a single book. Selection of the HPLC Method in Chemical Analysis is an inclusive go-to reference for HPLC method selection, development, and validation.- Addresses the various aspects of practice and instrumentation needed to obtain reliable HPLC analysis results- Leads researchers to the best choice of an HPLC method from the overabundance of information existent in the field- Provides criteria for HPLC method selection, development, and validation- Authored by world-renowned HPLC experts who have more than 60 years of combined experience in the field

Contents:

Start of the implementation of a new HPLC method

Short overviews of analystical techniques not containing an independent separation step

Short overviews of the main analytical techniques containing a separation step

Basic information regarding HPLC techniques

Properties of analytes and matrices determining HPLC selection

General aspects regarding the HPLC analytical column

RP-HPLC analytical columns

Polar analytical columns

Stationary phase and columns for ion exchange, ion-moderated, and ligand exchange chromatography

Stationary phases and columns for chiral chromatography

Stationary phases and columns for size exclusion

Solvents, buffers, and additives used in the mobile phase

Gradient elution

The practice of HPLC.

Notes:

Includes index.

Description based on print version record.

ISBN:

9780128037119

0128037113