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Novel Molecular Targets for Mood Disorders and Psychosis : Proceedings of a Workshop.
- Format:
- Book
- Author/Creator:
- Bain, Lisa J., author.
- Language:
- English
- Subjects (All):
- Affective disorders--Treatment.
- Affective disorders.
- Drug development.
- Physical Description:
- 1 online resource (89 pages)
- Edition:
- 1st ed.
- Place of Publication:
- Washington, D.C. : National Academies Press, 2021.
- Summary:
- Mood disorders - including depression and bipolar disorder - are common, disabling, and potentially lethal disorders, characterized by a shortened lifespan from comorbid medical illness and rising suicide rates. Medications for these conditions have been shown to be insufficiently effective in the majority of people who take them, and there remains a tremendous unmet medical need. Recent advances towards understanding the mechanisms of action for psychiatric medicines have led to the identification of potential novel molecular targets and agents for treating mood disorders. While these promising avenues for further investigation have re-energized scientific research in this area, many open questions remain. In response to this interest, the National Academies of Sciences, Engineering, and Medicine's Forum on Neuroscience and Nervous System Disorders convened a workshop in March 2021, Novel Molecular Targets for Mood Disorders and Psychosis.
- Contents:
- Introduction and Background
- 2 Current Drug Development Landscape and Limitations of Molecular Targets for Mood Disorders and Psychosis
- 3 Targeting Glutamate Receptors for Treatment-Resistant Depression
- 4 Targeting GABA Receptors to Treat Postpartum Depression
- 5 Emerging Drug Targets
- 6 Regulatory Considerations for the Next Generation of Psychiatric Drugs
- 7 Ethical and Legal Principles Related to the Clinical Use of Psychoactive Drugs
- 8 Potential Next Steps and Future Opportunities.
- Notes:
- Description based on publisher supplied metadata and other sources.
- ISBN:
- 9780309685917
- 0309685915
- OCLC:
- 1285955588
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