Electrospinning for tissue regeneration / edited by Lucy A. Bosworth and Sandra Downes.

Format:

Book

Contributor:

Bosworth, Lucy A.

Downes, Sandra.

Series:

Woodhead Publishing Series in Biomaterials

Language:

English

Subjects (All):

Tissue engineering.

Electrospinning.

Physical Description:

1 online resource (425 p.)

Place of Publication:

Cambridge ; Philadelphia, Pa. : Woodhead Pub., 2011.

Language Note:

English

Summary:

Electrospinning is a simple and highly versatile method for generating ultrathin fibres with diameters ranging from a few micrometres to tens of nanometres. Although most commonly associated with textile manufacturing, recent research has proved that the electrospinning technology can be used to create organ components and repair damaged tissues. Electrospinning for tissue regeneration provides a comprehensive overview of this innovative approach to tissue repair and regeneration and examines how it is being employed within the biomaterials sector.The book opens with an introduction to

Contents:

Cover; Electrospinning for tissue regeneration; Copyright; Contents; Contributor contact details; Part I Fundamentals of electrospinning; 1 Introduction to electrospinning; 1.1 Introduction; 1.2 Basic concepts; 1.3 Morphology and structural formation; 1.4 Parameters; 1.5 Apparatus; 1.6 Materials; 1.7 Applications; 1.8 Future trends; 1.9 References; 2 Polymer chemistry; 2.1 Introduction; 2.2 Natural polymers; 2.3 Synthetic degradable polymers; 2.4 Conclusions; 2.5 References; 3 The electrospinning process, conditions and control; 3.1 Introduction; 3.2 Solution parameters

3.3 Processing parameters3.4 Ambient parameters; 3.5 Conclusions; 3.6 References; 4 Regulatory issues relating to electrospinning; 4.1 Introduction; 4.2 Regulation of materials in regenerative medicine; 4.3 Future trends; 4.4 Sources of further information and advice; 4.5 References; Part II Electrospinning for tissue regeneration; 5 Bone tissue regeneration; 5.1 Introduction; 5.2 Principles of bone biology; 5.3 Strategies for bone regeneration; 5.4 Fabrication of scaffolds for bone tissue engineering; 5.5 Potential materials for scaffolds; 5.6 Osteoporosis: a growing problem

5.7 Strategies for the treatment of bone defects5.8 Conclusions and future trends; 5.9 References; 6 Cartilage tissue regeneration; 6.1 Introduction; 6.2 Culture of chondrogenic cells for implantation; 6.3 Electrospun nanofibre scaffolds; 6.4 Future trends; 6.5 References; 7 Muscle tissue regeneration; 7.1 Introduction to skeletal muscle; 7.2 Skeletal muscle injuries; 7.3 Mechanical properties of skeletal muscle; 7.4 Tissue engineering; 7.5 Contractile force; 7.6 Conductive elements; 7.7 Conclusion and future trends; 7.8 References; 8 Tendon tissue regeneration

8.1 Introduction: tendon tissue8.2 Tendon structure and composition; 8.3 Tendon pathology; 8.4 Clinical need; 8.5 Tissue engineering; 8.6 Cell response to electrospun bundles; 8.7 Mechanical properties of electrospun bundles; 8.8 Conclusions and future trends; 8.9 Acknowledgements; 8.10 References; 9 Nerve tissue regeneration; 9.1 Introduction; 9.2 Clinical problems in nerve tissue therapy; 9.3 Nerve tissue engineering; 9.4 Biomimetic nanoscaffolds for peripheral nerve regeneration; 9.5 Stem cell therapy with nanofibre for nerve regeneration; 9.6 Conclusion and perspectives; 9.7 References

10 Heart valve tissue regeneration10.1 Introduction; 10.2 Tissue to be replaced: heart valves; 10.3 Specific tissue requirements as a blueprint for scaffold properties; 10.4 Selection of scaffold material; 10.5 Scaffold properties to meet tissue requirements; 10.6 Future trends; 10.7 Acknowledgment; 10.8 References; 11 Bladder tissue regeneration; 11.1 Structural/functional properties of the bladder; 11.2 Bladder disease and the need for bladder substitution; 11.3 Electrospun and other scaffolds for bladder tissue engineering; 11.4 Electrospinning fit for purpose; 11.5 Future trends

11.6 Conclusions

Notes:

Description based upon print version of record.

Includes bibliographical references and index.

ISBN:

0-85709-291-X

OCLC:

866858727