WHO guidelines for plague management : revised recommendations for the use of rapid diagnostic tests, fluoroquinolones for case management and personal protective equipment for prevention of post-mortem transmission / World Health Organization.

Format:

Book

Author/Creator:

World Health Organization, author, issuing body.

Language:

English

Subjects (All):

Plague--History.

Plague.

Disease management.

Physical Description:

1 online resource (xi, 47 pages) : illustrations

Edition:

1st ed.

Other Title:

WHO guidelines for plague management

Place of Publication:

Geneva : World Health Organization, [2021]

Summary:

These guidelines provide recommendations on the use of rapid diagnostic tests for the various forms of plague in plague-endemic areas and during outbreaks. They also provide recommendations on the choice of antimicrobial medicines for the different forms (including whether fluoroquinolones should be introduced as a first-line medicine of choice) and the use of personal protective equipment for the safe handling of potentially infectious human remains. The guidelines are intended to serve as the basis for developing national guidelines, taking into account the available resources and other determinants in each country. They are aimed at clinicians practising in primary and secondary care, public health professionals preparing for or responding to outbreaks, and policy- and decision-makers.

Contents:

Intro

Acknowledgements

Abbreviations

Executive summary

Introduction

1.1 Background

1.2 Rationale for these guidelines

1.3 Target audience

1.4 Aim and objective

Guideline development process and methods

2.1 Scoping and developing key questions

2.2 Contributors to the guideline development process

2.3 Declarations of interests

2.4 Identifying, appraising and synthesizing evidence

2.5 Formulating recommendations

2.5.1 Evidence-to-decision considerations

2.5.2 Group decision-making

2.6 Peer review

2.7 Stakeholders and the public

2.8 Guiding principles

Recommendations

3.1 Use of F1RDT for plague

3.1.1 Background

3.1.2 Use of F1RDT to detect pneumonic plague in plague-endemic areas

3.1.3 Use of F1RDT to diagnose pneumonic plague in patients in areas where an outbreak is in progress

3.1.4 Use of F1RDT to detect bubonic plague in plague-endemic areas

3.1.5 Use of F1RDT to diagnose bubonic plague in patients in areas where an outbreak is in progress

3.2 Antibiotics for treating plague

3.2.1 Background

3.2.2 Development of recommendations on antibiotics for treating plague

3.2.3 Supporting evidence

3.2.4 Use of fluoroquinolones for treating pneumonic or septicaemic plague

3.2.5 Use of doxycycline for treating pneumonic or septicaemic plague

3.2.6 Use of fluoroquinolones for treating bubonic plague

3.2.7 Use of fluoroquinolones for treating plague meningitis

3.2.8 Use of fluoroquinolones for postexposure presumptive treatment

3.2.9 Antibiotics for pre-exposure chemoprophylaxis

3.3 Use of personal protective equipment

3.3.1 Background

Monitoring and evaluation

Knowledge gaps and future research

5.1 F1RDT for plague

5.2 Antibiotics for treating plague.

5.3 Risk of transmission from the dead body of a person who was infected with plague

5.4 Recommendations for additional guidance

Updating

References.

Notes:

Includes bibliographical references.

Description based on: online resource; title from PDF title page (NCBI, viewed November 3, 2022).