Uveal melanoma : biology and management / Eric H. Bernicker, editor ; Amy C. Schefler, associate editor.

Format:

Book

Contributor:

Bernicker, Eric H., editor.

Schefler, Amy C., editor.

Language:

English

Subjects (All):

Uvea--Tumors.

Uvea.

Melanoma.

Tumors.

Genre:

Electronic books.

Physical Description:

1 online resource : illustrations (chiefly color)

Place of Publication:

Cham : Springer, [2021]

System Details:

text file

Summary:

This book provides a comprehensive examination of uveal melanoma, a rare neoplasm that carries a very high mortality and whose natural history makes it fairly unique among adult tumors. Split into three sections, this book explores the basic science behind the disease and inherited genetic syndromes that predispose some patients, as well as the pathology and use of gene expression profiling to determine risk of recurrence. It also focuses on the management of the primary tumor in the eye, including surgical intervention and lesion imaging. Elucidating treatment options for metastatic disease, the book reviews chemotherapy agents and immunotherapy approaches, as well as liver-directed therapies, cellular therapies, and various treatments after primary treatment but before the development of metastases. Uveal Melanoma: Biology and Management is the most up-to-date and comprehensive text devoted solely to this disease and will be useful to medical oncologists, ophthalmologists, radiation therapists, interventional radiologists, pathologists, molecular biologists and immunology researchers, as well as trainees in those fields.

Contents:

Molecular Basis of Uveal Melanoma and Emerging Therapeutic Targets

Clinical/Commercial

Genetic Testing in UM

BAP1 Tumor Predisposition Syndrome

Pathology of Uveal Melanoma

Epidemiology of Uveal Melanoma and Potential Clusters

Gene Expression Profiling in the Management of Uveal Melanoma

Surgical Considerations of Radiation Plaques and Enucleation

Uveal Melanoma: Imaging

Radiation Therapy in Ocular Melanoma

Late Complications of Radiation Therapy in Uveal Melanoma

Nanoparticles for the Treatment of Uveal Melanoma

Screening Schedules for Metastatic Disease

Adjuvant Therapy of Uveal Melanoma Liver-Directed Therapies for Hepatic Metastases

Systemic Therapy for Metastatic Uveal Melanoma

Cell Therapy for Uveal Melanoma.

Notes:

Includes index.

Online resource; title from PDF title page (SpringerLink, viewed August 16, 2021).

ISBN:

9783030781170

3030781178

OCLC:

1262966581

Access Restriction:

Restricted for use by site license.