Polyendocrine disorders and endocrine neoplastic syndromes / Annamaria Colao, Marie-Lise Jaffrain-Rea, Albert Beckers, editors.

Format:

Book

Contributor:

Colao, Annamaria.

Jaffrain-Rea, Marie-Lise.

Beckers, Albert.

Series:

Endocrinology (Series : 2018- )

Endocrinology

Language:

English

Subjects (All):

Endocrine glands--Diseases--Diagnosis.

Endocrine glands.

Endocrine glands--Diseases--Treatment.

Endocrine glands--Diseases.

Genre:

Electronic books.

Physical Description:

1 online resource (435 pages).

Place of Publication:

Cham : Springer, 2021.

System Details:

text file

Summary:

This comprehensive reference book is meant to support clinicians in the diagnosis and treatment of polyendocrine diseases and endocrine neoplastic syndromes. Although a large majority of endocrine diseases present as sporadic cases, an increasing proportion can be identified as part of a polyendocrine or systemic syndrome. These include autoimmune endocrine diseases, which may be part of autoimmune polyendocrine disorders (APS) or rare complex disorders such as POEMS (polyneuropathy, organomegaly, endocrinopathy, M-protein and skin changes) or IPEX (immune dysregulation, polyendocrinopathy, enteropathy, X-linked) syndromes. On the other hand, endocrine tumors may develop in a variety of clinical conditions, including multiple endocrine neoplasia (MEN) syndromes, syndromic diseases such as McCune Albright or Carneys complex, or peculiar familial associations such as pheochromocytoma/paraganglioma syndromes. The book discusses the significant advances that have been made in the clinical and genetic characterization of such entities, with major implications in terms of diagnosis and clinical management - with special attention to emerging syndromes, familial screening , multidisciplinarity and multimodal treatment. This volume is intended for clinicians, residents, specialists and physicians involved in the diagnosis and treatment of affected patients, including specialists in endocrinology, internal medicine, oncology , genetics and imaging.

Contents:

Intro

Series Preface

Volume Preface

Contents

About the Editors

Contributors

Part I: Polyendocrine Disorders in Autoimmune and Systemic Diseases

1 Autoimmune Polyendocrine Syndromes (APS) or Multiple Autoimmune Syndromes (MAS)

Introduction

Criteria for the Diagnosis of Autoimmune Diseases

Classification of Autoimmune Diseases

Natural History of Autoimmune Diseases

Old Classification of APS

New Classifications of APS/MAS

Hypothesis on the Pathogenesis of APS/MAS

APS/MAS-1

Historical Features

Frequency and Epidemiology

Animal Models of APS/MAS-1

Genetics of APS/MAS-1

Main Clinical Manifestations of APS/MAS-1

Chronic Mucocutaneous Candidiasis (CMC)

Chronic Hypoparathyroidism (CH)

Autoimmune Addisonś Disease (AAD)

Minor Autoimmune Diseases

Premature Ovarian Failure (POF)

Autoimmune Gastritis (AG)

Auto-Immune Thyroid Diseases (AITD)

Type 1 Diabetes Mellitus (DM-1)

Alopecia Areata (AA)

Vitiligo

Autoimmune Hepatitis (AH)

Autoimmune Enteropathy (AE)

Splenic Atrophy (SA)

Pituitary Failure (PF)

Renal Diseases

Pulmonary Diseases (PD)

Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP)

Vasculitis

Ectodermal Dystrophy

Cancer

Other Rare Diseases

Total Number of Diseases in the Italian Cohort of APS/MAS-1

Diseases of APS/MAS-1 and Related Autoantibodies

New Diagnostic Criteria for APS/MAS-1

How to Manage Patients with ASP/MAS-1

When to Investigate for AIRE Gene Mutations

Therapy

APS/MAS-2

Animal Models

Genetics of APS/MAS-2

Frequency and Epidemiology of APS/MAS-2

Main Clinical Manifestations of APS/MAS-2

Autoimmune Addisonś Disease (AAD)

Autoimmune Thyroid Diseases (AITD)

Type 1 Diabetes Mellitus (DM-I)

Combinations of the Three Major Diseases

Incomplete or Subclinical Forms of APS/MAS-2

Alopecia

Celiac Disease

Other Autoimmune Diseases

Autoimmune Diseases and Autoantibodies in APS/MAS-2

APS/MAS-3

General Considerations

Frequency of APS/MAS-3

A New Classification of APS/MAS-3

Genetics of APS/MAS-3

APS/MAS 3A: Association Between AITD and Other Autoimmune Endocrine Diseases

AITD and DM-1

AITD and Hirataś Disease (HD)

AITD and Hypergonadotropic Hypogonadism (HH)

AITD and Lymphocytic Adenohypophysitis (LAH)

AITD and Lymphocytic Neurohypophysitis (LNH)

AITD and Chronic Hypoparathyroidism (CH)

AITD and Lymphocytic Mastopathy

Incomplete APS/MAS 3A

APS/MAS-3B: Association Between AITD and Other Autoimmune Diseases of the Digestive System

AITD and Autoimmune Gastritis (AG)

AITD and Pernicious Anemia (PA)

AITD and Celiac Disease (CD)

AITD and Autoimmune Hepatitis (AH)

AITD and Primary Biliary Cholangitis (PBC)

Notes:

Description based upon print version of record.

AITD and Primary Sclerosing Cholangitis (PSC).

Includes index.

Other Format:

Print version: Colao, Annamaria Polyendocrine Disorders and Endocrine Neoplastic Syndromes

ISBN:

9783319894973

3319894978

OCLC:

1263872356

Access Restriction:

Restricted for use by site license.