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Twentieth Century Mouse Genetics : A Historical and Scientific Review.

Elsevier ScienceDirect eBook - Biochemistry, Genetics and Molecular Biology 2021 Available online

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Format:
Book
Author/Creator:
Erickson, Robert P.
Language:
English
Genre:
Electronic books.
Physical Description:
1 online resource (346 pages)
Place of Publication:
San Diego : Elsevier Science & Technology, 2021.
System Details:
text file
Contents:
Front cover
Half title
Full title
Copyright
Dedication
Contents
Preface
References
Acknowledgements
Introduction
Reference
1
The origins of mouse genetics and the discovery of the T -locus
France
United Kingdom
Germany
The United States
The discovery of the T- locus
Notes
2
The evolutionary modern synthesis, t -haplotypes in the wild, and reproductive isolation
Genetics and natural selection-the search for mutants in the wild
The Re-discovery of t alleles in wild mice
Leslie Clarence Dunn, 1893-1974
Studies on prezygotic species isolation in Mus musculus and domesticus
Update
T/t complex effects on odorant discrimination
Update on other odorant systems and subspecies isolation
Haldane's rule, sex-chromosomal hybrid sterility genes
Update on sex chromosomes and hybrid sterility
The T/t complex and hybrid sterility
3
Linkage studies, cytogenetics, and the discovery that t -haplotypes consist of a series of inversions-an over-the-Cen ...
General linkage studies in mice
The Haldane-Mitchison Scientific Clan
John Scott Haldane, 1860-1936
John Burdon Sanderson Haldane, 1892-1964
Naomi Mitchison, nee Haldane, 1897-1999
Denis Mitchison, 1919-
John Murdoch Mitchison, 1922-2011
Nicholas Avrion Mitchison, 1928-
Timothy John Mitchison, 1961-
General cytogenetic studies in mice
t -allele linkage and cytogenetic studies
4
Developmental genetics and recessive t -lethals
Early studies of the developmental genetics of the T/t complex
Other early developmental genetic models
New tools for mouse developmental genetics
Studies of T/t complex developmental genes, continued
Pre-implantation lethals
Post-implantation lethals
T/T Homozygous lethality
5
More population genetics with particular attention to the effects of t -allele mediated transmission ratio distortion
Population genetics of t-alleles
6
Mutation studies including those targeting the T/t -complex-a century long project
Mutagenesis by ionizing radiation
Chemical mutagenesis
Insertional mutagenesis
Mutagenic studies of the T/t complex
7
Immunogenetics and the failed search for t -antigens-from mid-century and continuing to it's end
Blood groups and the major histocompatability complex
Tolerance
A well-studied minor histocompatibility antigen: H-Y
Association of the T/t -complex with histocompatibility antigens
The failed search for t -complex antigens
Ernst Caspari, 1909-1988
8
Gametogenesis and the genetics of gametes, including t -haplotype segregation distortion
Oogenesis
Spermatogenesis
Notes:
Description based upon print version of record.
Spermatozoal RNA.
Other Format:
Print version: Erickson, Robert P. Twentieth Century Mouse Genetics
ISBN:
9780128240175
0128240172
OCLC:
1266905663
Access Restriction:
Restricted for use by site license.

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