Ion channels : channel chemical biology, engineering, and physiological function / edited by Daniel L. Minor, Jr., Henry M. Colecraft.

Format:

Book

Contributor:

Minor, Daniel L., Jr., editor.

Colecraft, Henry M., editor.

Series:

Methods in enzymology ; 0076-6879 v. 654.

Methods in enzymology, 0076-6879 ; volume 654

Language:

English

Subjects (All):

Ion channels.

Physical Description:

xviii, 434 pages : illustrations (some color) ; 24 cm.

Edition:

First edition.

Other Title:

Channel chemical biology, engineering, and physiological function

Place of Publication:

Cambridge, MA : Academic Press, an imprint of Elsevier, 2021.

Contents:

Section I. Methods to engineer ion channels to probe different aspects of channel structure-function and regulation. Selection and validation of orthogonal tRNA/synthetase pairs for the encoding of unnatural amino acids across kingdoms / Grace D. Galles, Daniel T. Infield, Ryan A. Mehl, and Christopher A. Ahern ; Ion channel engineering using protein trans-splicing / Debayan Sarkar, Hendrik Harms, Iacopo Galleano, Zeshan Pervez Sheikh, and Stephan Alexander Pless ; ANAP : A versatile, fluorescent probe of ion channel gating and regulation / Michael C. Puljung ; Engineering voltage sensing phosphatase (VSP) / Hidekazu Tsutsui, Natsuki Mizutani, and Yasushi Okamura ; Probing ion channel neighborhoods using proximity proteomics / Gabriel Redel-Traub, Guoxia Liu, Steven O. Marx, and Jared Kushner

Section II. Methods to control and characterize ion channel function. Controlling ion channel trafficking by targeted ubiquitination and deubiquitination / Travis J. Morgenstern and Henry M. Colecraft ; Production of recombinant venom peptides as tools for ion channel research / Chandamita Saikia, Gili Ben-Nissan, Eitan Reuveny, and Izhar Karbat ; Tethered peptide toxins for ion channels / Ruiming Zhao and Steve A.N. Goldstein ; Stretch and poke stimulation for characterizing mechanically activated ion channels / Amanda H. Lewis and Jörg Grandl ; Optogenetic control of calcium influx in mammalian cells / Yi-Tsang Lee, Rui Chen, Yubin Zhou, and Lian He ; A method for assessing ionic and molecular permeation in connexin hemichannels / Pablo S. Gaete and Jorge E. Contreras

Section III. Methods to characterize ion channel function and expression in physiology and disease. Choroid plexus epithelial cells as a model to study nongenomic steroid signaling and its effect on ion channel function / Monika Haoui, Natalie True Petersen, Ida Björkgren, Dong Hwa Chung, and Polina V. Lishko ; Single organelle measurements of melanosome pH using the novel ratiometric indicator RpHiMEL / Jessica L. Scales, Donald C. Koroma, and Elena Oancea ; Long read transcript profiling of ion channel splice isoforms / Nicola A.L. Hall, Syed M. Husain, Hami Lee, and Elizabeth M. Tunbridge ; Evaluating BEST1 mutations in pluripotent stem cell-derived retinal pigment epithelial cells / Alec Kittredge, Yu Zhang, and Tingting Yang ; Functional evaluation of human ion channel variants using automated electrophysiology / Carlos G. Vanoye, Christopher H. Thompson, Reshma R. Desai, Jean-Marc DeKeyser, Liqi Chen, Laura J. Rasmussen-Torvick, Leah J. Welty, and Alfred L. George, Jr. ; In vitro discovery of novel prokaryotic ion channel candidates for antiarrhythmic gene therapy / Tianyu Wu, Hung X. Nguyen, and Nenad Bursac.

Notes:

Includes bibliographical references.

Other Format:

ebook version :

ISBN:

9780128239247

0128239247

OCLC:

1223012752