Oncology / edited by Thankamma Ajithkumar, Ann Barrett, Helen Hatcher, Sarah Jefferies.

Format:

Book

Contributor:

Ajithkumar, T. V. (Thankamma V.), editor.

Barrett, Ann (Emeritus professor of oncology), editor.

Hatcher, Helen M., editor.

Jefferies, Sarah Jane, editor.

Oxford University Press.

School of Medicine Library Fund.

Series:

Oxford desk reference series

Oxford desk reference

Language:

English

Subjects (All):

Oncology--Handbooks, manuals, etc.

Oncology.

Neoplasms.

Medical Subjects:

Neoplasms.

Genre:

Handbooks and manuals.

Physical Description:

1 online resource : illustrations.

polychrome

Edition:

Second edition.

Place of Publication:

Oxford : Oxford University Press, 2021.

System Details:

text file

Contents:

1 Clinical approach to suspected cancer p. 1

1.2 Lung cancer p. 2

1.3 Mesothelioma p. 2

1.4 Breast cancer p. 2

1.5 Urologicai cancer p. 3

1.6 Nervous system tumours p. 3

1.7 Upper gastrointestinal cancer p. 4

1.8 Lower gastrointestinal cancer p. 4

1.9 Gynaecological cancer p. 5

1.10 Haematological cancer p. 5

1.11 Head and neck cancer p. 6

1.12 Thyroid cancer p. 6

1.13 Bone cancer and sarcoma p. 6

1.14 Skin cancer-melanoma p. 7

1.15 Skin cancer-non-melanoma p. 7

1.16 Further reading and internet resources p. 7

2 Concepts of multidisciplinary management p. 8

2.1 Cancer prevention p. 9

2.2 Cancer screening p. 11

2.3 Cancer genetics p. 12

2.4 Genetic counselling p. 17

2.5 Principles of cancer diagnosis and management p. 22

2.6 Principles of surgical oncology p. 27

2.7 Radiotherapy p. 29

2.8 Systemic therapy p. 33

2.9 Clinical trials p. 42

3 Tumours of the head and neck p. 48

3.1 Principles of management for cancer of the head and neck p. 49

3.2 Tumours of the eye, orbit, and ear p. 54

3.3 Salivary gland cancers p. 56

3.4 Nose, nasal cavity, and paranasal sinuses p. 58

3.5 Nasopharynx p. 59

3.6 Lip and oral cavity p. 61

3.7 Oropharynx p. 62

3.8 Hypopharynx p. 63

3.9 Larynx p. 64

3.10 Uncommon tumours of the head and neck p. 66

3.11 Management of neck nodes p. 67

4 Tumours of the central nervous system p. 70

4.1 Primary brain tumours p. 71

4.2 Clinicopathology of brain tumours p. 72

4.3 Presentation and general management of primary brain tumours p. 74

4.4 Surgical management of primary brain tumours p. 76

4.5 Radiotherapy for primary brain tumours p. 78

4.6 Chemotherapy and new agents for primary brain tumours p. 80

4.7 Outcome and management of recurrence in primary brain tumours p. 81

4.8 Summary of management for primary brain tumours p. 84

4.9 Brain metastases overview p. 85

4.10 Treatment options for brain metastases p. 87

4.11 Outcome and summary for brain metastases p. 89

4.12 Spinal cord tumours overview p. 90

4.13 Management of spinal cord tumours p. 92

4.14 Outcome in spinal tumours p. 93

4.15 Further reading and internet resources p. 94

5 Thoracic tumours p. 96

5.1 Primary tracheal tumours p. 97

5.2 Lung cancer overview p. 97

5.3 Diagnosis and staging of lung cancer p. 98

5.4 Pathology of lung cancer p. 100

5.5 Treatment of stage I and II non-small cell lung cancer p. 103

5.6 Treatment of stage III non-small cell lung cancer p. 104

5.7 Treatment of stage IV non-small ceil lung cancer p. 106

5.8 Small cell lung cancer p. 109

5.9 Bronchial carcinoid p. 111

5.10 Large cell neuroendocrine carcinoma p. 112

5.11 Malignant pleural mesothelioma p. 112

5.12 Thymic tumours p. 114

6 Breast cancer p. 117

6.1 Breast cancer overview p. 118

6.2 Clinical presentation, diagnosis, and staging of breast cancer p. 119

6.3 Management of breast cancer: Carcinoma in situ p. 125

6.4 Loco-regional treatment of invasive breast cancer: Surgery p. 126

6.5 Loco-regional treatment of invasive breast cancer: Radiation therapy p. 127

6.6 Systemic treatment for early breast cancer p. 128

6.7 Management of locally advanced breast cancer p. 132

6.8 Management of recurrent and metastatic breast cancer (MBC) p. 133

6.9 Male breast cancer p. 137

6.10 BRCA and hereditary breast cancer p. 138

7 Cancers of the gastrointestinal system p. 140

7.1 Epidemiology of oesophageal cancer p. 141

7.2 Treatment of localized disease for oesophageal cancer p. 143

7.3 Treatment of advanced disease for oesophageal cancer p. 145

7.4 Epidemiology of gastric cancer p. 145

7.5 Treatment of localized disease for gastric cancer p. 148

7.6 Treatment of advanced disease for gastric cancer p. 149

7.7 Hepatocellular cancer p. 151

7.8 Biliary tract tumours overview p. 158

7.9 Pancreatic cancer overview p. 165

7.10 Treatment of resectable pancreatic cancer p. 168

7.11 Treatment of unresectable and metastatic pancreatic cancer p. 170

7.12 Uncommon pancreatic tumours p. 171

7.13 Tumours of the small intestine p. 172

7.14 Colorectal cancer overview p. 174

7.15 Clinical features, diagnosis, and staging of colorectal cancer p. 176

7.16 Colorectal cancer: Localized disease p. 179

7.17 Adjuvant treatment for colorectal cancer p. 181

7.18 Treatment of advanced colorectal cancer p. 185

7.19 Prognosis, follow-up, and management of recurrence of colorectal cancer p. 189

7.20 Anal cancer p. 191

8 Cancers of the genitourinary system p. 196

8.1 Cancer of the kidney p. 197

8.2 Non-surgical management of cancer of the kidney p. 200

8.3 Urothelial and bladder cancer overview p. 202

8.4 Management of localized and muscle invasive disease of bladder cancer p. 204

8.5 Management of advanced and metastatic disease of bladder cancer p. 206

8.6 Management of non-transitional urothelial cancer p. 208

8.7 Cancer of the ureter and renal pelvis p. 209

8.8 Prostate cancer overview p. 210

8.9 Clinical features, diagnosis, staging, natural history, screening, and prognosis of prostate cancer p. 211

8.10 Treatment of localized disease for prostate cancer p. 214

8.11 Treatment of advanced disease for prostate cancer p. 217

8.12 Detection and treatment of recurrence of prostate cancer p. 218

8.13 Palliative care and symptom control for prostate cancer p. 220

8.14 Testicular cancer overview p. 221

8.15 Clinical features, diagnosis, TIN, staging, and prognosis for testicular cancer p. 223

8.16 Management of low stage seminoma testicular cancer p. 225

8.17 Management of low stage non-seminoma testicular cancer p. 227

8.18 Prognosis and management of advanced testicular cancer disease p. 228

8.19 Testicular cancer follow-up p. 230

8.20 Penile cancer overview p. 231

8.21 Management of penile cancer p. 232

9 Cancers of the female genital system p. 234

9.1 Cervical cancer overview p. 235

9.2 Clinical features, investigations, staging, and prognosis of cervical cancer p. 236

9.3 Management of cervical cancer p. 238

9.4 Recurrent cervical cancer p. 241

9.5 Role of chemotherapy p. 241

9.6 Treatment-related morbidity for cervical cancer p. 242

9.7 Newer approaches to cervical cancer p. 242

9.8 Endometrial cancer p. 243

9.9 Management of endometrial cancer p. 246

9.10 Role of radiotherapy p. 247

9.11 Role of chemotherapy and hormonal agents p. 249

9.12 Recurrence and metastasis p. 250

9.13 Uterine sarcomas p. 251

9.14 Epithelial ovarian cancer p. 255

9.15 Investigations, staging, and prognosis for epithelial ovarian cancer p. 257

9.16 Early stage disease of epithelial ovarian cancer p. 258

9.17 Advanced stage disease of epithelial ovarian cancer p. 259

9.18 Epithelial ovarian cancer: Recurrent disease p. 261

9.19 Epithelial ovarian cancer: Palliative care issues and conclusion p. 263

9.20 Malignant ovarian germ cell tumours p. 264

9.21 Management of malignant ovarian germ cell tumours p. 266

9.22 Prognosis, surveillance, and management of recurrence in malignant ovarian germ cell tumours p. 268

9.23 Sex cord-stromal tumours p. 269

9.24 Borderline ovarian tumours p. 272

9.25 Uncommon ovarian tumours p. 273

9.26 Gestational trophoblastic disease overview p. 273

9.27 Special situations p. 278

9.28 Cancers of the vulva and vagina p. 281

10 Cancers of the skin p. 287

10.1 Introduction, clinical features, and staging of cutaneous melanoma p. 288

10.2 Management of loco-regional disease for cutaneous melanoma p. 289

10.3 Management of metastatic disease for cutaneous melanoma p. 291

10.4 Non-cutaneous melanoma p. 295

10.5 Basal cell carcinoma p. 296

10.6 Squamous cell carcinoma p. 300

10.7 Merkel cell carcinoma p. 302

10.8 Kaposi's sarcoma p. 303

10.9 Malignant skin adnexal tumours p.

305

10.10 Skin cancer in organ transplant recipients p. 306

11 Cancers of the musculoskeletal system p. 308

11.1 Bone tumours overview p. 309

11.2 Osteosarcoma p. 312

11.3 Ewing's sarcoma p. 314

11.4 Rare bone tumours p. 317

11.5 Soft tissue sarcomas overview p. 319

11.6 Management of localized soft tissue sarcoma p. 321

11.7 Management of locally advanced and metastatic disease for soft tissue sarcomas p. 323

11.8 Retroperitoneal sarcoma p. 325

11.9 Gastrointestinal stromal tumour p. 326

11.10 Future directions in soft tissue sarcoma p. 328

12 Tumours of the haemopoietic system p. 329

12.1 Hodgkin lymphoma p. 330

12.2 Clinical features, diagnosis, and staging for Hodgkin lymphoma p. 332

12.3 Treatment of early stage Hodgkin lymphoma p. 333

12.4 Treatment of advanced stage Hodgkin lymphoma p. 335

12.5 Management of relapsed Hodgkin lymphoma p. 336

12.6 Long-term toxicities and fertility issues of Hodgkin lymphoma p. 338

12.7 Non-Hodgkin lymphoma p. 339

12.8 Clinical features of non-Hodgkin lymphoma p. 341

12.9 Treatment of low-grade disease p. 343

12.10 Diffuse large B-cell lymphoma p. 344

12.11 Mantle cell lymphoma p. 345

12.12 Cutaneous non-Hodgkin lymphomas p. 346

12.13 Extranodal involvement of non-Hodgkin lymphoma p. 347

12.14 Adult acute lymphoblastic leukaemia p. 349

12.15 Adult acute myeloid leukaemia p. 352

12.16 Chronic myeloid leukaemia p. 357

12.17 Chronic lymphocytic leukaemia p. 362

12.18 Treatment for chronic lymphocytic leukaemia p. 364

12.19 Hairy cell leukaemia p. 366

12.20 Myelodysplastic syndrome overview p. 368

12.21 Clinical features, staging, and prognosis of myelodysplastic syndrome p. 370

12.22 Treatment for myelodysplastic syndrome p. 370

12.23 Multiple myeloma p. 374

12.24 Staging, prognosis, and treatment response criteria for multiple myeloma p. 377

12.25 Treatment for multiple myeloma p. 378

12.26 Solitary plasmacytoma p. 384

12.27 Monodonal gammopathy of undetermined significance p. 385

12.28 Smouldering myeloma p. 386

12.29 Waldenström's macroglobulinemia p. 387

12.30 Amyloidosis p. 388

12.31 POEMS syndrome p. 389

12.32 Heavy chain disease p. 390

12.33 Histiocyte disorders p. 391

13 Endocrine tumours p. 393

13.1 Thyroid cancer overview p. 394

13.2 Treatment of differentiated thyroid cancer p. 396

13.3 Treatment of medullary carcinoma thyroid p. 399

13.4 Treatment of anaplastic carcinoma thyroid p. 401

13.5 Primary thyroid lymphoma p. 402

13.6 Parathyroid cancer p. 403

13.7 Adrenocortical carcinoma p. 404

13.8 Neuroendocrine tumours p. 406

14 Paediatric tumours p. 410

14.1 Leukaemia p. 411

14.2 Lymphoma p. 413

14.3 Paediatric central nervous system tumours p. 416

14.4 Paediatric solid tumours and kidney tumours p. 421

14.5 Sarcomas p. 422

14.6 Neuroblastoma p. 423

14.7 Other paediatric tumours and Langerhans cell histiocytosis p. 424

15 Oncological emergencies and acute oncology p. 425

15.1 Oncological emergencies and acute oncology p. 426

15.2 Tumour lysis syndrome p. 426

15.3 Hypercalcaemia p. 427

15.4 Hyponatraemia p. 428

15.5 Hyperkalemia p. 429

15.6 Hypoglycaemia p. 430

15.7 Hyperuricaemia p. 430

15.8 Febrile neutropenia p. 431

15.9 Catheter associated infections p. 433

15.10 Nausea, vomiting, and diarrhoea p. 433

15.11 Vascular complications p. 434

15.12 Stridor and airway obstruction p. 436

15.13 Superior vena cava obstruction p. 437

15.14 Gastrointestinal obstruction p. 438

15.15 Urinary tract obstruction p. 438

15.16 Thrombocytopenia and disseminated intravascular coagulation p. 439

15.17 Gastrointestinal bleeding p. 440

15.18 Genitourinary bleeding p. 441

15.19 Cardiorespiratory p. 442

15.20 Cardiac tamponade p. 442

15.21 Pleural effusion p. 443

15.22 Brain metastases and raised intracranial pressure p. 444

15.23 Spinal cord compression p. 444

15.24 Impending and pathological fractures p. 445

15.25 Immunotherapy-related emergencies p. 446

16 Special situations in oncology p. 450

16.1 Teenage and young adult malignancies p. 451

16.2 Cancer in older people p. 453

16.3 Cancer in pregnant women p. 456

16.4 Cancer of unknown primary site p. 459

16.5 Fertility and cancer p. 461

16.6 Late effects p. 462

16.7 Cancer survivorship p. 465

16.8 Travel p. 466

16.9 Insurance p. 468

16.10 Vaccination p. 469

16.11 Lifestyle choices after cancer p. 472

16.12 Complementary therapies p. 475

16.13 Supportive care during chemotherapy p. 477

17 Palliative care p. 482

17.1 Pain management p. 483

17.2 Nausea and vomiting p. 490

17.3 Malignant bowel obstruction p. 493

17.4 Constipation p. 495

17.5 Diarrhoea p. 496

17.6 Hiccups p. 497

17.7 Depression p. 498

17.8 Delirium p. 499

17.9 Oral care p. 501

17.10 Cancer-related fatigue p. 502

17.11 Cancer cachexia p. 503

17.12 Breathlessness p. 504

17.13 Cough p. 505

17.14 Haemoptysis p. 506

17.15 Symptom clusters p. 507

17.16 End of life care p. 508

18 Clinical management of cancers-flowcharts p. 513.

Notes:

Electronic reproduction. Oxford Available via World Wide Web.

Description based on online resource; title from resource web page (Oxford Medicine Online, viewed on May 10, 2021).

Includes bibliographical references and index.

Previous edition: 2011.

Local Notes:

Acquired for the Penn Libraries with assistance from the School of Medicine Library Fund.

ISBN:

9780191807169

0191807168

Publisher Number:

99988020983

Access Restriction:

Restricted for use by site license.