Chronic myeloid leukemia / Rüdiger Hehlmann, editor.

Format:

Book

Contributor:

Hehlmann, Rüdiger, editor.

Series:

Hematologic malignancies (Series)

Hematologic malignancies

Language:

English

Subjects (All):

Chronic myeloid leukemia.

Genre:

Electronic books.

Physical Description:

1 online resource (279 pages).

Edition:

Second edition.

Place of Publication:

Cham : Springer, 2021.

System Details:

text file

Summary:

This book provides state-of-the-art reviews of key issues and recent developments relating to chronic myeloid leukemia (CML), acquainting the reader with advances in research, treatment, and promotion of public health. Among the management topics addressed are the choices, advantages, and pitfalls of first-, second-, and third-line treatments; the European LeukemiaNet recommendations; management of adverse effects of tyrosine kinase inhibitors (TKI); management of CML blast crisis; management of pregnancy in the context of CML; the role of hematopoietic cell transplantation; the current experience with TKI discontinuation; and the value of interferon α in improving the outcome of TKI treatment. Various aspects of relevance to treatment outcome are discussed, including prognostic scores, molecular monitoring (principles and interlaboratory standardization), and response-related predictors of survival. Furthermore, updates are provided on the increasing prevalence of CML and its implications and on the changing cost of care for CML, taking into account the impact of availability of generic imatinib.

Contents:

Cytogenetics of Chronic Myeloid Leukemia (CML)

The Biology and Pathogenesis of Chronic Myeloid Leukaemia

Epidemiology of Chronic Myeloid Leukemia.-Imatinib and the first line CML Therapy

CML Therapy: A Focus on Second and Third Generation Tyrosine Kinase Inhibitors

Adverse events associated with ATP-competitive BCR-ABL1 tyrosine kinase inhibitors in chronic myeloid leukemia

Pharmacoeconomic considerations for tyrosine kinase inhibitors in the treatment of chronic myeloid leukemia

Standardization of molecular monitoring for chronic myeloid leukemia: 2021 update

Prognostic Scores for Patients with Chronic Myeloid Leukemia under Particular Consideration of Disease-Specific Death

A Review and an Update of European LeukemiaNet Recommendations for the Management of Chronic Myeloid Leukemia

The Role of Hematopoietic Stem Cell Transplantation in CML

CML end-phase and blast crisis: implications and management

The Interferon-alpha Revival in CML

Managing Pregnancy in Chronic Myeloid Leukemia

Response-Related Predictors of Survival and of Treatment Free Remission in CML

Discontinuation or cessation of tyrosine kinase inhibitor treatment in Chronic myeloid leukemia patients with deep molecular response.

Notes:

Online resource; title from PDF title page (SpringerLink, viewed June 16, 2021).

Other Format:

Print version: Hehlmann, Rüdiger Chronic Myeloid Leukemia

ISBN:

9783030719135

3030719138

OCLC:

1256238503

Access Restriction:

Restricted for use by site license.