Monoclonal antibodies in headache : from bench to patient / Antoinette Maassen van den Brink, Paolo Martelletti, editors.

Format:

Book

Contributor:

Maassen van den Brink, Antoinette, editor.

Martelletti, Paolo, editor.

Series:

Headache (Springer (Firm)) 2197-652X

Headache, 2197-652X

Language:

English

Subjects (All):

Headache--Treatment.

Headache.

Monoclonal antibodies--Therapeutic use.

Monoclonal antibodies.

Genre:

Electronic books.

Physical Description:

1 online resource (x, 172 pages) : color illustrations.

Place of Publication:

Cham, Switzerland : Springer, [2021]

System Details:

text file

Summary:

Intended to promote a more appropriate and modern therapeutic approach to migraine management, this book is the first to deal with monoclonal antibodies in this context. Authored by the most respected migraine experts from around the globe and drawing on the lessons learned in both clinical trials and clinical practice, it reviews the current state of knowledge on this important therapeutic innovation, which has produced impressive data in randomized controlled trials, and the efficacy and safety of which have been confirmed in day-to-day real-world use. Given its scope, the book will appeal to a broad range of specialists, including pharmacologists, clinical pharmacologists, neurologists and internists, but also to residents and medical students.

Contents:

The CGRP family of neuropeptides and their receptors in the trigeminovascular system

Pharmacology; where do the mAbs act, gepants vs mAbs

Monoclonal Antibody Biology

Guidelines for clinical trials

Human Models

CGRP Antibodies for Animal Models of Primary and Secondary Headache Disorders

Galcanezumab

Eptinezumab

Erenumab

Fremanezumab

Potential side effects and pregnancy

Real-world data, clinical practice so far

Migraine vs Cluster headache and potential other indications.

Other Format:

Print version:

ISBN:

9783030690328

3030690326

OCLC:

1249514334

Access Restriction:

Restricted for use by site license.