The neuropathology of schizophrenia / Matthew Williams, editor.

Format:

Book

Contributor:

Williams, Matthew (Editor), editor.

Language:

English

Subjects (All):

Schizophrenia--Pathophysiology.

Schizophrenia.

Nervous system--Diseases.

Nervous system.

Genre:

Electronic books.

Physical Description:

1 online resource

Place of Publication:

Cham, Switzerland : Springer, [2021]

System Details:

text file

Summary:

In the past few decades, neuropathology has witnessed a resurgence. The rise of structural and functional imaging techniques has allowed pathological studies to target regions of special interest as revealed by whole-brain techniques, and the development of comprehensive software packages has facilitated cellular and pathological measurements. Furthermore, a new generation of antibodies and improved staining methods has made the field more accessible to researchers and revealed more detail than could once have been envisaged. Perhaps most important of all has been the sourcing of high-quality tissue through modern, large-scale databases covering multiple tissue banks, removing much of the heterogeneity that had made repeat studies all but impossible. The Neuropathology of Schizophrenia reviews the field following these recent improvements in techniques and contrasting more modern methods against older studies. This book presents the current state of neuropathological knowledge in schizophrenia by means of examination of neuropathology as informed by functional systems. It starts by considering the frontal cortical region, a particularly well-examined region of the brain, before moving through other cortical regions, subcortical pathways and the deep white matter. In addition, potential new routes for investigation are considered, particularly in glial cells.

Contents:

Introduction

A note of neuroanatomy

Gross Pathology in Schizophrenia

Frontal Cortex

Temporal Cortex

The amygdala, hippocampus, fornix and nucleus basalis

The Cingulate Cortex

Parietal and Occipital Lobes

The Basal Ganglia

The Thalamus

The Neuropathology of White Matter in Schizophrenia

Glial Cells.

Notes:

Online resource; title from PDF title page (SpringerLink, viewed April 14, 2021).

Other Format:

Print version:

ISBN:

9783030683085

3030683087

OCLC:

1244626378

Access Restriction:

Restricted for use by site license.