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An introduction to smooth muscle mechanics / Chun Y. Seow.
- Format:
- Book
- Author/Creator:
- Seow, Chun Y., author.
- Language:
- English
- Subjects (All):
- Smooth muscle--Mechanical properties.
- Smooth muscle.
- Muscle, Smooth--physiology.
- Medical Subjects:
- Muscle, Smooth--physiology.
- Physical Description:
- 1 online resource (xi, 177 pages) : illustrations (some color
- Edition:
- Second edition.
- Place of Publication:
- Newcastle upon Tyne, UK : Cambridge Scholars Publishing, 2021.
- [Place of publication not identified] : [publisher not identified], [2021]
- System Details:
- text file
- Contents:
- Anatomy and physiological function of smooth muscle p. 1
- Activation of smooth muscle p. 5
- Similarities and differences between smooth and striated muscles p. 10
- Chapter 2 Structural Basis of Smooth Muscle Contraction p. 12
- Ultrastructure - transverse views p. 12
- Ultrastructure - longitudinal views p. 17
- Myofilaments p. 22
- Intermediate filaments, microtubules, dense bodies, and dense plaques p. 24
- Mitochondria, sarcoplasmic reticulum, Golgi apparatus, and caveolae p. 24
- Structures for intracellular and extracellular force transmission p. 26
- Contractile units in smooth muscle p. 33
- Chapter 3 Basic Muscle Mechanics p. 38
- Force and stress p. 38
- Length and strain p. 41
- Stiffness: elasticity and viscoelasticity p. 45
- Classical analysis using springs and dashpots p. 45
- Stress relaxation p. 46
- Creep p. 49
- Power law analysis of stress relaxation and creep p. 53
- Tissue response to cyclic stress or strain p. 54
- Least squares fit for estimation of tissue elastance and resistance p. 56
- Mechanical components of contracting muscle - a minimal model p. 57
- Isometric contraction p. 59
- Isotonic contraction p. 61
- Isotonic quick release p. 61
- The "slack-test" for determining maximal shortening velocity p. 63
- Normalization of measurements of muscle properties p. 65
- Normalization of force p. 67
- Normalization of shortening and velocity p. 67
- Normalization of power output p. 67
- Chapter 4 The Actomyosin Cross-bridge Cycle p. 68
- Mechanical cycle coupled to ATP hydrolysis p. 68
- Cross-bridge, contractile unit, and the muscle stiffness p. 70
- Variations in force/stiffness ratio due to detention of bridges in different states p. 72
- Factors affecting the cross-bridge cycle in smooth muscle p. 76
- Chapter 5 Force-Velocity Relationship p. 78
- Hill's force-velocity equation p. 78
- Force-velocity characteristics of smooth muscle p. 81
- Force-power relationship p. 82
- Changes in force-velocity parameters in partially activated muscles p. 84
- Changes in Vmax due to internal loads p. 85
- Changes in force-velocity parameters due to rearrangement of contractile units p. 88
- Connection between the Hill equation and the cross-bridge kinetics p. 90
- Chapter 6 Length-Force Relationship and Length Adaptation p. 94
- Theoretical considerations of active force as a function of length p. 95
- Ascending limb of the length-force curve in smooth muscle p. 98
- Manifestation of the instantaneous length-force and force-velocity relationships during muscle shortening p. 100
- Passive Length-force relationship p. 102
- Unloading of the parallel element bearing passive tension p. 103
- Load transfer during an isotonic contraction p. 105
- Length adaptation and active force p. 107
- Length adaptation of passive tension and stiffness p. 110
- Chapter 7 Instrumental Analysis of Force and Length Measurements p. 112
- Signal and noise p. 113
- Propagation of measurement errors due to random noise p. 114
- Addition and subtraction p. 114
- Multiplication and division p. 115
- Force transducer p. 115
- Length transducer p. 119
- Analog-to-digital (A/D) converter p. 120
- Signal processing p. 121
- A brief review of electronics p. 121
- Simple analog methods for signal processing p. 122
- High-pass filter p. 122
- Low-pass filter p. 122
- Analog methods involving operational amplifiers p. 123
- Inverting amplifier p. 124
- Non-inverting amplifier p. 125
- Differential amplifier p. 126
- Summing amplifier p. 127
- Integrator p. 127
- Differentiator p. 128
- Digital methods for signal processing p. 129
- Trace averaging p. 129
- Trace smoothing p. 130
- Limitations in noise reduction techniques p. 135
- Electric field stimulation (EFS) of smooth muscle p. 135.
- Notes:
- Includes bibliographical references and index.
- Electronic reproduction. Ann Arbor, MI Available via World Wide Web.
- Description based on print version record.
- Local Notes:
- Acquired for the Penn Libraries with assistance from the Rudolph G. Schmieder Fund.
- ISBN:
- 9781527562288
- 152756228X
- Publisher Number:
- 99986444125
- Access Restriction:
- Restricted for use by site license.
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