Evolutionary concepts in immunology / Robert Jack, Louis Du Pasquier.

Format:

Book

Author/Creator:

Jack, Robert S., author.

Du Pasquier, Louis, author.

Language:

English

Subjects (All):

Immunology.

Immune System Phenomena.

Biological Evolution.

Medical Subjects:

Immune System Phenomena.

Biological Evolution.

Physical Description:

xvi, 145 pages : illustrations ; 25 cm

Place of Publication:

Cham, Switzerland : Springer, [2019]

Summary:

Immunology is a nodal subject that links many areas of biology. It permeates the biosciences, and also plays crucial roles in diagnosis and therapy in areas of clinical medicine ranging from the control of infectious and autoimmune diseases to tumour therapy. Monoclonal antibodies and small molecule modulators of immunity are major factors in the pharmaceutical industry and now constitute a multi billion dollar business. Students in these diverse areas are frequently daunted by the complexity of immunology and the astonishing array of unusual mechanisms that go to make it up. Starting from Dobzhanskys famous slogan, "Nothing in biology makes sense except in the light of evolution", this book will serve to illuminate how evolutionary forces shaped immunity and thus provide an explanation for how many of its counter intuitive oddities arose. By doing so it will provide a conceptual framework on which students may organise the rapidly growing flood of immunological knowledge. -- Provided by publisher.

Contents:

What makes evolution tick?

From Unicellular to Metazoan transition

Innate immunity

The triumph of individualism: evolution of somatically generated adaptive immune systems

The other side of the arms race.

Notes:

Includes bibliographical references and index.

ISBN:

9783030186661

3030186660

OCLC:

1090922268