Modeling Excitable Tissue : The EMI Framework / edited by Aslak Tveito, Kent-Andre Mardal, Marie E. Rognes.

Format:

Book

Author/Creator:

Tveito, Aslak, Editor.

Contributor:

Tveito, Aslak, 1961- Editor.

Mardal, Kent-Andre, Editor.

Rognes, Marie E., Editor.

Series:

Reports on Computational Physiology, 2730-7743 ; 7

Language:

English

Subjects (All):

Biomathematics.

Mathematics.

Mathematical models.

Mathematical and Computational Biology.

Applications of Mathematics.

Mathematical Modeling and Industrial Mathematics.

Local Subjects:

Mathematical and Computational Biology.

Applications of Mathematics.

Mathematical Modeling and Industrial Mathematics.

Physical Description:

1 online resource (XVII, 100 p. 25 illus. in color.)

Edition:

1st ed. 2021.

Place of Publication:

Cham : Springer International Publishing : Imprint: Springer, 2021.

Language Note:

English

Summary:

This open access volume presents a novel computational framework for understanding how collections of excitable cells work. The key approach in the text is to model excitable tissue by representing the individual cells constituting the tissue. This is in stark contrast to the common approach where homogenization is used to develop models where the cells are not explicitly present. The approach allows for very detailed analysis of small collections of excitable cells, but computational challenges limit the applicability in the presence of large collections of cells.

Contents:

Derivation of a cell-based mathematical model of excitable cells

A cell-based model for ionic electrodiffusion in excitable tissue

Modeling cardiac mechanics on a subcellular scale

Operator splitting and finite difference schemes for solving the EMI model

Solving the EMI equations using finite element methods

Iterative solvers for EMI models

Improving neural simulations with the EMI model

Index.

ISBN:

3-030-61157-4

OCLC:

1243532880