Design and analysis of clinical trials for economic evaluation and reimbursement : an applied approach using SAS and STATA / Iftekhar Khan, University College London, UK.

Format:

Book

Author/Creator:

Iftiqar, author.

Series:

Chapman & Hall/CRC biostatistics series.

Chapman & Hall/CRC Biostatistics Series

Language:

English

Subjects (All):

Medical economics.

Clinical trials--Economic aspects.

Clinical trials.

Cost effectiveness.

Physical Description:

1 online resource (332 p.)

Edition:

1st edition

Other Title:

Design and analysis of clinical trials for economic evaluation and reimbursement

Place of Publication:

Boca Raton : CRC Press, [2016]

System Details:

text file

Summary:

Economic evaluation has become an essential component of clinical trial design to show that new treatments and technologies offer value to payers in various healthcare systems. Although many books exist that address the theoretical or practical aspects of cost-effectiveness analysis, this book differentiates itself from the competition by detailing how to apply health economic evaluation techniques in a clinical trial context, from both academic and pharmaceutical/commercial perspectives. It also includes a special chapter for clinical trials in Cancer.Design & Analysis of Clinical Trials for Economic Evaluation & Reimbursement is not just about performing cost-effectiveness analyses. It also emphasizes the strategic importance of economic evaluation and offers guidance and advice on the complex factors at play before, during, and after an economic evaluation.Filled with detailed examples, the book bridges the gap between applications of economic evaluation in industry (mainly pharmaceutical) and what students may learn in university courses. It provides readers with access to SAS and STATA code. In addition, Windows-based software for sample size and value of information analysis is available free of charge—making it a valuable resource for students considering a career in this field or for those who simply wish to know more about applying economic evaluation techniques.The book includes coverage of trial design, case report form design, quality of life measures, sample sizes, submissions to regulatory authorities for reimbursement, Markov models, cohort models, and decision trees. Examples and case studies are provided at the end of each chapter.Presenting first-hand insights into how economic evaluations are performed from a drug development perspective, the book supplies readers with the foundation required to succeed in an environment where clinical trials and cost-effectiveness of new treatments are central. It also includes thought-provoking exercises for use in classroom and seminar discussions.

Contents:

Front Cover; Contents; Preface; Author; Acronyms; Chapter 1: Introduction to Economic Evaluation; Chapter 2: Health Economic Evaluation Concepts; Chapter 3: Designing Cost-Effectiveness into a Clinical Trial; Chapter 4: Analysing Cost Data Collected in a Clinical Trial; Chapter 5: Quality of Life in Economic Evaluation; Chapter 6: Modelling in Economic Evaluation; Chapter 7: Sensitivity Analyses; Chapter 8: Sample Size and Value of Information for Cost-Effectiveness Trials; Chapter 9: Mixed Treatment Comparisons, Evidence Synthesis; Chapter 10: Cost-Effectiveness Analyses of Cancer Trials

Chapter 11: The Reimbursement EnvironmentReferences; Bibliography; Back Cover

Notes:

A Chapman and Hall book.

Includes bibliographical references.

Description based on online resource; title from PDF title page (ebrary, viewed December 11, 2015).

ISBN:

1-04-005980-5

0-429-09835-9

1-4665-0548-6

9780429098352

OCLC:

928989804