Lipid signaling and metabolism edited by James M. Ntambi

Format:

Book

Contributor:

Ntambi, James M., editor.

Language:

English

Subjects (All):

Lipids--Metabolism.

Lipids.

Cellular signal transduction.

Lipid Metabolism.

Signal Transduction.

Medical Subjects:

Lipid Metabolism.

Signal Transduction.

Physical Description:

1 online resource

Place of Publication:

London Academic Press 2020

Summary:

With recent technological advances and mass-scale sequencing approaches, our understanding of lipid metabolism and signaling, and its role in health and disease processes, has increased significantly. The maintenance of metabolic health has been shown to require complex regulation of metabolic processes in several tissues, and extensive crosstalk among tissues and organs. Lipids act not only as constituents of cellular membranes, but as key signaling mediators, serving new and unexpected biological, metabolic, and cellular functions

Lipid Signaling and Metabolism provides foundational knowledge and methods to examine lipid metabolism and bioactive lipid signaling mediators that regulate a broad sprectrum of biological processes and disease states. Here, world-renowned investigators, first offer a basic examiniation of general lipid, metabolism, intracellular lipid storage and utilization, followed by an in-depth discussion of lipid signaling and metabolism across disease areas, including obesity, diabetes, fatty liver disease, inflammation, cancer, cardiovascular disease, and mood-related disorders. Throughout, authors demonstrate how expanding our understanding of lipid mediators in metabolism and signaling enables opportunities for novel therapeutics. Emphasis is placed on bioactive lipid metabolism and research that have been impacted by new technologies, and their potential to transform precision medicine. -- page 4 of cover

Contents:

Homeostatic control of membrane lipid biosynthesis in bacteria Daniela Albanesi, Ana Arabolaza, Hugo Gramajo, Diego de Mendoza Lipid trafficking and signaling in plants Amanda M. Koenig, Christoph Benning, Susanne Hoffmann-Benning Sex as a modulator of lipid metabolism and metabolic disease Laurent Vergnes, Carrie Riestenberg, Karen Reue Local interactions in the bone marrow microenvironment and their contribution to system metabolic processes Kenneth T. Lewis, Ormond A. MacDonald Lipids in the transcriptional regulation of adipocyte differentiation and metabolism Shuwen Qian, Liang Guo, Qiqun Tang Lipid receptors and signaling in adipose tissue Ann V. Hertzel, Timothy D. O'Connell, David A. Bernlohr Adipocyte lipolysis and lipid-derived metabolite signaling Charlie Kirsh, Abigail M. Harris, Judith Simcox Regulation of intracellular lipid storage and utilization Alyssa S. Zembroski, Kimberly K. Buhman The lipid droplet as a signaling node Charles P. Najt, Douglas G. Mashek Lipid droplets in the immune response and beyond Sheetal Gandotra Fatty acids mediators and the inflammasome Frédérik Desmarais, Karl-F. Bergeon, James M. Ntambi, Eric Rassart, Catherine Mounier Identification and pathophysiological roles of LTB₄ receptors BLT1 and BLT2 Yumiko Ishii, Toshiaki Okuno, Takehiko Yokomizo The forkhead box O family in insulin action and lipid metabolism Sojin Lee, Cuiling Zhu, Jun Yamauchi, Ping Zhu, Xiaoyun Feng, Shen Qu, H. Henry Dong Interplays between nutritional and inflammatory signaling and fat metabolism in pathophysiology of NAFLD Juan Zheng, Ting Chen, Xin Guo, James M. Ntambi, Chaodong Wu Endocannabinoids: the lipid effectors of metabolic regulation in health and disease Tony Jourdan, Pascal Degrace, Isabel Gonzáles-Mariscal, Gergo Szanda, Joseph Tam Gut microbiota interaction in host lipid metabolism Rachel M. Golonka, Ahmed A. Abokor, James M. Ntambi, Matam Vijay-Kumar Insights into the metabolism of lipids in obesity and diabetes Ademola O. Ayeleso, Mashudu G. Matumba, James M. Ntambi, Emmanuel Mukwevho Lipid metabolic features of skeletal muscle in pathological and physiological conditions Yura Son, Chad M. Paton Sphingolipid mediators of cell signaling and metabolism Agnieszka Dobrzyn, Justyna Jankiewicz, Zuzanna Tracz-Gaszewska, Anna Filip, Aneta M. Dobosz, Ewelina Krogulec, Pawel Dobrzyn Role of bile acid receptors in the regulation of cardiovascular diseases Yuji Shiozaki, Audrey L. Keenan, Makoto Miyazaki Molecular mechanisms underlying effects of n-3 and n-6 fatty acids in cardiovascular diseases Denny Joseph Manual Kollareth, Chuchun L. Chang, Hylde Zirpoli, Richard J. Deckelbaum Lipid metabolism and signaling in cancer Elena Piccinin, James M. Ntambi, Antonio Moschetta Altered lipid metabolic homeostasis in Alzheimer's disease Oana C. Marian, Collin Tran, Anthony S. Don Role of xenosterols in health and disease Babunageswararao Kanuri, Vincent Fong, Shailendra B. Patel Adipose tissue development and metabolic regulation Hai P. Nguyen, Danielle Yi, Hei Sook Sul

Notes:

Includes index

Includes bibliographical references and index

Other Format:

Print version:

ISBN:

9780128194058

0128194057

OCLC:

1183915463

Access Restriction:

Restricted for use by site license