Biometals in autism spectrum disorders / Andreas M. Grabrucker.

Format:

Book

Author/Creator:

Grabrucker, Andreas M., author.

Language:

English

Subjects (All):

Autism spectrum disorders.

Metals in the body.

Autism Spectrum Disorder--drug therapy.

Trace Elements--therapeutic use.

Metals--therapeutic use.

Child Development Disorders, Pervasive.

Medical Subjects:

Autism Spectrum Disorder--drug therapy.

Trace Elements--therapeutic use.

Metals--therapeutic use.

Child Development Disorders, Pervasive.

Physical Description:

1 online resource

Place of Publication:

London, United Kingdom : Academic Press is an imprint of Elsevier, 2020.

Summary:

"Biometals in Autism Spectrum Disorders focuses on trace metals and autism. Compared to other references examining ASDs or metallomics, this book presents findings of abnormal metal homeostasis in ASD, providing an overview of current findings on trace metal biology, its role in ASD etiology, and how abnormal trace metal biology may be a common factor of several genetic and non-genetic causes of ASDs that were once considered unrelated. This comprehensive resource opens new vistas for the development of new therapies based on the targeted manipulation of trace metal homeostasis that will generate new awareness surrounding trace metal levels during pregnancy"-- ScienceDirect.

Contents:

Introduction to metallomics : the science of biometals

Measuring biometals

The history of metals in autism spectrum disorders

Essential trace metals and their function in brain development

Nonessential metals and their brain pathology

Biometals and nutrition in autism spectrum disorders

Linking trace metal abnormalities to autism—insights from epidemiological studies

The specific role of zinc in autism spectrum disorders

Animal models for trace metal abnormalities—links to autism

Animal models for autism—links to biometal abnormalities

Human stem cell models linking biometal abnormalities and autism

Extracerebral biometals in autism spectrum disorders : the gut–brain axis

Biometal homeostasis as a therapeutic strategy in autism spectrum disorders

Future perspectives : autism, a disorder of biometal imbalance?.

Notes:

Includes bibliographical references and index.

Online resource; title from PDF title page (ScienceDirect, viewed August 3, 2020).

Other Format:

Print version: Grabrucker, Andreas M. Biometals in autism spectrum disorders

ISBN:

0128211326

9780128211328

OCLC:

1181944613

Access Restriction:

Restricted for use by site license