Choroidal Neovascularization / edited by Jay Chhablani.

Format:

Book

Contributor:

Chhablani, Jay, editor.

SpringerLink (Online service)

Series:

Medicine (SpringerNature-11650)

Language:

English

Subjects (All):

Ophthalmology.

Local Subjects:

Ophthalmology.

Physical Description:

1 online resource (XVII, 433 pages) : 171 illustrations, 159 illustrations in color

Edition:

First edition 2020.

Contained In:

Springer Nature eBook

Place of Publication:

Singapore : Springer Singapore : Imprint: Springer, 2020.

System Details:

text file PDF

Summary:

The book discusses all aspects of choroidal neovascularization (CNV), including the basics, clinical conditions associated with CNV, clinical trials related to CNV, future directions and rehabilitation. The first section covers the pathogenesis, proposed mechanisms, disease models, histopathology and electronmicroscopy. The next section explores CNV secondary to various clinical conditions, such as age-related macular degeneration (AMD), myopia, and less common conditions like choroidal osteoma. The book also covers clinical features, imaging characteristics, and treatment approaches, as well as clinical trials in CNV conditions with recent updates. Lastly, it features chapters on stem cell therapy, gene therapy, new molecules, and lasers, as well as a section on rehabilitation, which addresses home monitoring and low vision aids. This book is intended for retina specialists, retina fellows and general ophthalmologists.

Contents:

Section I: History

History of choroidal neovascularization (CNV) - initial understanding and development

Section II: Basics

Pathogenesis - various proposed mechanisms

Histopathology - recent understanding in relationship with imaging

Electron microscopy - update in choroidal changes

Section III: Clinical classification

Neovascular age-related macular degeneration (AMD) - clinical features, imaging, protocols and outcomes

CNV secondary to pathologic myopia - clinical features, imaging and treatment outcomes

Pachychoroid related CNV - recent updates, imaging and outcomes

Inflammatory CNV - clinical features, imaging and treatment outcomes

Dystrophy related CNV - clinical features, imaging and treatment outcomes

CNV secondary to angioid streaks - clinical features, imaging and treatment protocols

Idiopathic CNV - clinical features, imaging and treatment outcomes

CNV associated with idiopathic juxtafoveal telangiectasia - clinical features, imaging and treatment outcomes

CNV associated with other causes - laser induced, idiopathic intracranial hypertension, choroidal osteoma, trauma, choroidal coloboma, choroidal nevus, etc

Peripapillary CNVM - overview of various causes, imaging features and treatment outcomes

Pediatric CNVM - overview of various causes, imaging features and treatment outcomes

Polypoidal choroidal vasculopathy (PCV) - clinical features, imaging and treatment outcomes

Section IV: Treatment options

Anti-VEGF current options - Ranibizumab, Bevacizumab, Aflibercept, Ziv-aflibercept, Conbercept

Photodynamic therapy - current status in anti-VEGF era

Surgical intervention - graft, retinal implant, the implantable miniature telescope, surgical removal of CNV, subretinal tissue plasminogen activator

Section V: Clinical trials

n-AMD trials - comprehensive overview of PDT and anti-VEGF trials in AMD

Myopic CNV trials - comprehensive overview of PDT and anti-VEGF trials in AMD

Non-AMD CNV trials - comprehensive overview of various trials in non-AMD related CNV causes

PCV trials - comprehensive overview of PDT and anti-VEGF trials in PCV

Section VI: Future directions

Stem cells in AMD - current status and future expectations

Newer molecules - newer targets in CNV and the upcoming research

Radiotherapy - role of radiotherapy and clinical trials

Other options - role of subthreshold laser, and other therapies in CNV

Section VII: Rehabilitation

Low vision aids

Peripheral vision development - newer approach for macular diseases

Monitoring techniques - advanced home monitoring techniques and initial experience.

Other Format:

Printed edition:

ISBN:

978-981-15-2213-0

9789811522130

Access Restriction:

Restricted for use by site license.