Introduction to proteins : structure, function, and motion / Amit Kessel, Nir Ben-Tal.

Format:

Book

Author/Creator:

Kessel, Amit, author.

Ben-Tal, Nir, author.

Contributor:

ProQuest ebook central.

Series:

Chapman and Hall/CRC mathematical & computational biology series

Chapman & Hall/CRC mathematical & computational biology series

Language:

English

Subjects (All):

Proteins.

Proteins--Structure-activity relationships.

Physical biochemistry.

Physical Description:

1 online resource.

polychrome

Edition:

Second edition.

Place of Publication:

Boca Raton, FL : CRC Press, [2018]

System Details:

text file

Contents:

Cover; Half Title; Abstact; Title; Copyrights; Contents; List Of Figures; List Of Tables; List Of Boxes; Preface; Changes In Second Edition; Acknowledgments; Authors; Physical Quantities Andconstants; List Of Acronyms; Chapter 1. Introduction; 1.1 Importance Of Proteins In Living Organisms; 1.1.1 Life, Proteins And Mysterious Forces; 1.1.2 Molecular Organization Of Living Organisms; 1.1.3 Proteins Have Numerous Biological Roles; 1.1.3.1 Catalysis Of Metabolic Processes; 1.1.3.2 Energy Transfer; 1.1.3.3 Gene Expression; 1.1.3.4 Transport Of Solutes Across Biological Membranes.

1.1.3.5 Cellular Communication1.1.3.6 Molecular Recognition; 1.1.3.7 Defense; 1.1.3.8 Forming Intracellular And Extracellular Structures; 1.1.3.9 Cell- And Tissue-specific Functions; 1.1.4 Physiological And Evolutionary Importance Of Proteins; 1.1.5 Medical, Industrial, And Social Importance Of Proteins; 1.1.5.1 Proteins As Drug Targets; 1.1.5.2 Proteins As Toxin Targets; 1.1.5.3 Industrial Applications Of Proteins; 1.2 Structural Complexity And Its Effect On Protein Function; 1.3 Noncovalent Interactions Between Atoms In Biomolecules; 1.3.1 Electrostatic Interactions; 1.3.1.1 Introduction.

1.3.1.2 Basic Principles1.3.1.3 Hydrogen Bonds; 1.3.1.4 Other Types Of Electrostatic Interactions; 1.3.2 Van Der Waals Interactions; 1.3.3 Nonpolar Interactions And Hydrophobic Effect; 1.3.4 Conclusions; 1.4 Summary; 1.5 Organization Of Book; Exercises; References; Chapter 2. Protein Structure; 2.1 Introduction; 2.1.1 Hierarchy In Protein Structure; 2.1.2 Coenzymes And Prosthetic Groups; 2.2 Primary Structure; 2.2.1 Amino Acids And Their Properties; 2.2.1.1 Amino Acid Structure; 2.2.1.2 Configurations Of Amino Acids; 2.2.1.3 Side Chain Properties; 2.2.1.4 Amino Acid Derivates In Proteins.

2.2.2 Peptide Bond2.3 Secondary Structure; 2.3.1 .-helix; 2.3.1.1 Geometry; 2.3.1.2 Intramolecular Interactions; 2.3.1.3 Amphipathic .-helices; 2.3.2 Non-.-helices; 2.3.2.1 310-helix; 2.3.2.2 .-helix; 2.3.2.3 Type Ii Polyproline Helix (ppii; 2.3.3 . Conformation; 2.3.4 Why Helices And Sheets; 2.3.5 Reverse Turns; 2.3.5.1 .-turn; 2.3.5.2 Loops; 2.3.6 Secondary Structure Preferences Of Amino Acids; 2.3.6.1 .-helix; 2.3.6.2 . Conformation; 2.4 Tertiary Structure; 2.4.1 Basic Properties Of Tertiary Structure; 2.4.1.1 Structural Properties Required For Complex Function.

2.4.1.2 Core Versus Surface2.4.1.3 Stabilizing Forces; 2.4.2 Architecture Of Proteins; 2.4.2.1 Simple Folding Motifs; 2.4.2.2 Complex Folds; 2.4.2.3 Domains; 2.4.2.4 Protein Classification; 2.4.2.5 Knotted Proteins; 2.4.3 Evolutionary Conservation Of Structure And Function In Proteins; 2.4.3.1 Interests Of Individual Versus Those Of Species; 2.4.3.2 Structure Conservation: Evolutionary Mechanisms; 2.4.3.3 Evolution Of Function; 2.4.4 Water Molecules Inside Proteins; 2.5 Quaternary Structure; 2.5.1 Introduction; 2.5.2 Characteristics; 2.5.2.1 Dimensions And Complexity; 2.5.2.2 Symmetry.

Notes:

Electronic reproduction. Ann Arbor, MI Available via World Wide Web.

Description based on online resource; title from digital title page (viewed on October 29, 2018).

ISBN:

9781498747189

1498747183

9781315113876

1315113872

Publisher Number:

99984962761

Access Restriction:

Restricted for use by site license.