A practical manual of diabetes in pregnancy / edited by David R. McCance, Michael Maresh, David A. Sacks.

Format:

Book

Contributor:

McCance, David R., editor.

Maresh, Michael, editor.

Sacks, David A., editor.

Language:

English

Subjects (All):

Diabetes in pregnancy.

Physical Description:

1 online resource (431 pages) : illustrations (some color)

Edition:

Second edition.

Place of Publication:

Hoboken, New Jersey : Wiley Blackwell, 2018.

Summary:

A PRACTICAL MANUAL OF DIABETES IN PREGNANCY The second edition of A Practical Manual of Diabetes in Pregnancy offers a wealth of new evidence, new material, new technologies, and the most current approaches to care. With contributions from a team of international experts, the manual is highly accessible and comprehensive in scope. It covers topics ranging from preconception to postnatal care, details the risks associated with diabetic pregnancy, and the long-term implications for the mother and baby. The text also explores recent controversies and examines thorny political pressures. The manual's treatment recommendations are based on the latest research to ensure pregnant women with diabetes receive the best possible care. The text takes a multi-disciplinary approach that reflects best practice in the treatment of diabetes in pregnancy. The revised second edition includes: * New chapters on the very latest topics of interest * Contributions from an international team of noted experts * Practical, state-of-the-art text that has been fully revised with the latest in clinical guidance * Easy-to-read, accessible format in two-color text design * Illustrative case histories, practice points, and summary boxes, future directions, as well as pitfalls and what to avoid boxes * Multiple choice questions with answers in each chapter Comprehensive and practical, the text is ideal for use in clinical settings for reference by all members of the multi-disciplinary team who care for pregnant women with diabetes. The manual is also designed for learning and review purposes by trainees in endocrinology, diabetes, and obstetrics.

Contents:

Intro

Title Page

Copyright Page

Contents

Contributors

Foreword

Preface

Section I Introduction

Chapter 1 Epidemiology of Diabetes in Pregnancy

Prevalence of Total Hyperglycemia in Pregnancy

Prevalence of Known Pre-Gestational Diabetes in Pregnancy

Prevalence of Hyperglycemia First Detected in Pregnancy

Public Health Impact of Hyperglycemia in Pregnancy

Multiple-Choice Questions

Chapter 2 Pathophysiology of Diabetes in Pregnancy

Maternal Metabolic Adaptation to Pregnancy

Insulin Resistance in Pregnancy

Nutrient Excess and Metabolic Dysfunction

Insulin Resistance and Glucose Intolerance

Metabolic Plasticity in Pregnancy

Pre-gestational Diabetes

Summary and Future Directions for Research

References

Chapter 3 The Placenta in a Diabetic Pregnancy

Normal Development

The Placenta in Diabetes

The Role of the Insulin/LGF System and Leptin on the Placenta in Diabetes

Influence of Fetal Sex on Placental Function in GDM

Placental Methylation

Summary

Questions

Section II Gestational Diabetes

Chapter 4 Screening for Gestational Diabetes

Introduction

Definition

Should we Screen for Gestational Diabetes?

Screening Methods

Costs of Screening

Conclusions

Multiple-Choice Question

Chapter 5 Diagnostic Criteria for Hyperglycemia in Pregnancy

Gestational Diabetes: Historical Development

Importance of Overt Diabetes in Pregnancy

Rationale for Diagnosing Maternal Hyperglycemia During Pregnancy

Basing Treatment on Improving Outcomes

Diagnosis in the First Trimester

Chapter 6 Lifestyle Treatment

Lifestyle Intervention in Obese Pregnant Women

Systematic Reviews on Intervention Trials.

Is It Possible that Intervention Might Be Harmful?

Ongoing Studies and Meta‐Analyses

Comparison of Studies

Future Directions

Chapter 7 Obesity and Diabetes in Pregnancy

Definitions

Physiology and Pathophysiology

Glucose Metabolism in GDM and Obesity

Lipid and Adipose Tissue Metabolism in GDM and Obese Pregnancies

Inflammation in Obesity and GDM in Pregnancy

In Utero Exposure to Obesity and GDM, and Later Offspring Health

Summary and Future Research

Chapter 8 Metabolic Abnormalities in Gestational Diabetes

Gestational Diabetes Mellitus: A Chronic Metabolic Disorder

Metabolic Syndrome in Women with Gdm

Lipid Profiles in Women with Gdm

Blood Pressure in Women with GDM

Inflammation in Women with GDM

Adipokine Dysregulation in Women with GDM

Metabolic Abnormalities Before Pregnancy and in Early Gestation Prior to the Diagnosis of GDM

Future Perspectives

Chapter 9 Maternal Risk After the Gestational Diabetes Mellitus Pregnancy

Maternal Sequelae of GDM After Delivery

Recommendations for Postpartum Glucose Screening

Recommendations for Behavior Modification

FutureDirections

Section III Diabetes Preceding Pregnancy

Chapter 10 Pre-Pregnancy Care in Type 1 and Type 2 Diabetes

Background

History of Pre-Pregnancy Care

Is Pre-Pregnancy Care Effective?

Why Do Women not Attend Pre-Pregnancy Care?

Components of a Pre-Pregnancy Service

Preconception Counseling

Pre-Pregnancy Care

Future Research

Chapter 11 Malformations

Epidemiology

Pathogenesis

Prevention

Detection and Management

Multiple-Choice Questions.

References

Chapter 12 Provision of Pregnancy Care

Guidelines for the Provision of Care

Aims of Multidisciplinary Joint Antenatal Diabetes Care

Organization: Members of the Multidisciplinary Team

Standardization of Schedules and Documentation

Special Needs

Problems with Provision of Maternity Care and Clinical Governance

The Way Forward

Editor's Note: A Us Perspective

Chapter 13 Problems Encountered More Frequently in Women with Type 1 Diabetes

Hypoglycemia

Hypoglycemic Unawareness

Autonomic Neuropathy

Diabetic Ketoacidosis

Stillbirth

Carbohydrate Counting and Type 1 Diabetes

Acknowledgment

Chapter 14 Problems Encountered More Frequently in Women with Type 2 Diabetes

Case History

Prevalence of Type 2 Diabetes

Preconception Counseling with Type 2 Diabetes

Diabetic Complications in Type 2 Diabetes

Pregnancy Complications

Postpartum Management

Chapter 15 Advances in Oral Anti‐Diabetes Drugs in Pregnancy

Sulfonylureas and Meglitinides

Metformin

Alpha-Glucosidase Inhibitors

Pparγ Agonists

Dipeptidyl Peptidase-4 (Dpp4) Inhibitors

GLP1 Receptor Agonists

Sodium-Glucose Co-Transporter-2 (Sglt2) Inhibitors

Breastfeeding

Chapter 16 Advances in Insulin Therapy

Continuous Subcutaneous Insulin Infusion

Continuous Glucose Monitoring

Sensor-Augmented Pump (SAP) Therapy

Closed-Loop Insulin Delivery Systems

Conclusions and Future Directions

Acknowledgments

Chapter 17 Putting Pregnant Women with Diabetes on the Pump

Initiating Insulin Pump Therapy.

Changing Insulin Requirements During Pregnancy

Steroids for Fetal Lung Maturation

Other Considerations Specific to Pregnancy

The Peripartum Period

Breastfeeding and the Postpartum Period

Chapter 18 Pregnancy, Perinatal, and Fertility Outcomes Following Bariatric Surgery

Classifications of Bariatric Surgery

Fertility

Contraception

Surgery-to-Conception Interval

Miscarriage

Preterm Labor

Hypertensive Disorders of Pregnancy

Gestational Diabetes Mellitus

Cesarean Section

Fetal Outcomes

Chapter 19 Fetal Surveillance

Pathophysiology of Fetal Compromise in Diabetes in Pregnancy

Accelerated Fetal Growth

Fetal Surveillance in Pre-gestational Diabetes (Type 1 or Type 2) and Gestational Diabetes Mellitus (Gdm)

Fetal Surveillance Methods: What is the Future?

Practical Approaches to Fetal Surveillance

Research Directions

Chapter 20 Complications in Pregnancy: Hypertension and Diabetic Nephropathy in Diabetes in Pregnancy

Hypertension in the Nonpregnant Diabetic Population

Hypertensive Disorders in Pregnancy

Practical Aspects of Detecting Hypertension in Pregnancy

Principles for Treatment of Hypertension in Pregnancy

Choice of Antihypertensive Drugs for Use Before and During Pregnancy

Antihypertensive Drugs During Breastfeeding

Chapter 21 Retinopathy in Diabetic Pregnancy

Overview of Diabetic Retinopathy Classification

Risk Factors for Progression of Diabetic Retinopathy

Risk Factors for Diabetic Retinopathy Progression During Pregnancy.

Possible Mechanisms of Diabetic Retinopathy Progression During Pregnancy

Clinical Management of Retinopathy Before, During, and After Pregnancy

Section IV Delivery and Postnatal Care

Chapter 22 Delivery and Postdelivery Care: Obstetric Management of Labor, Delivery, and the Postnatal Period for Women with Type 1, Type 2, or Gestational Diabetes Mellitus

Timing of Delivery

Mode of Delivery

Planned Cesarean Delivery - Practical Issues

Induction of Labor - Practical Issues

Specific Obstetric Issues in the First Stage of Labor

Specific Obstetric Issues in the Second Stage of Labor

Specific Issues Postnatally

Follow-Up Arrangements

Chapter 13 Diabetic Management in Labor, Delivery, and Postdelivery

Before Delivery

During Delivery

Diabetes Type

Insulin Infusion Regimens

Maternal Glucose Control Postpartum

Summary and Future Research Directions

Chapter 24 Delivery and Postdelivery Care: Care of the Neonate

Care of the Healthy Infant After Well-Controlled Diabetes in Pregnancy

Neonatal Complications - Etiology and Management

Long-Term Outcomes

Summary - Minimizing Risk

Chapter 25 Postpartum Contraception for Women with Diabetes

Important Contraceptive Safety Considerations in Women With Diabetes

Timing of Contraceptive Initiation

Contraceptive Options by Method

Case Follow-Up

Chapter 26 Breastfeeding and Diabetes

Breastfeeding and Diabetes

The Impact of Diabetes on Lactogenesis.

The Effect of Diabetes on the Composition of Breast Milk.

Notes:

Includes bibliographical references at the end of each chapters and index.

Description based on print version record.

ISBN:

9781119043799

1119043794

9781119043775

1119043778

9781119043805

1119043808

OCLC:

989519910