Micro-Electrode-Dot-Array Digital Microfluidic Biochips : Design Automation, Optimization, and Test Techniques / by Zipeng Li, Krishnendu Chakrabarty, Tsung-Yi Ho, Chen-Yi Lee.

Format:

Book

Author/Creator:

Li, Zipeng, computer engineer, author.

Chakrabarty, Krishnendu, author.

Ho, Tsung-Yi, author.

Lee, Chen-Yi, author.

Contributor:

SpringerLink (Online service)

Series:

Engineering (Springer-11647)

Language:

English

Subjects (All):

Electronic circuits.

Biomedical engineering.

Microprocessors.

Circuits and Systems.

Biomedical Engineering and Bioengineering.

Processor Architectures.

Local Subjects:

Circuits and Systems.

Biomedical Engineering and Bioengineering.

Processor Architectures.

Physical Description:

1 online resource (XIII, 144 pages) : 98 illustrations, 80 illustrations in color

Edition:

First edition 2019.

Contained In:

Springer eBooks

Place of Publication:

Cham : Springer International Publishing : Imprint: Springer, 2019.

System Details:

text file PDF

Summary:

This book provides an insightful guide to the design, testing and optimization of micro-electrode-dot-array (MEDA) digital microfluidic biochips. The authors focus on the characteristics specific for MEDA biochips, e.g., real-time sensing and advanced microfluidic operations like lamination mixing and droplet shape morphing. Readers will be enabled to enhance the automated design and use of MEDA and to develop a set of solutions to facilitate the full exploitation of design complexities that are possible with standard CMOS fabrication techniques. The book provides the first set of design automation and test techniques for MEDA biochips. The methods described in this book have been validated using fabricated MEDA biochips in the laboratory. Readers will benefit from an in-depth look at the MEDA platform and how to combine microfluidics with software, e.g., applying biomolecular protocols to software-controlled and cyberphysical microfluidic biochips. Presents a method for droplet size-aware high-level synthesis, targeting reservoir placement, operation scheduling, module placement, and routing of droplets of various sizes in a MEDA biochip; Enables efficient and adaptive error recovery, through a probabilistic-timed-automata (PTA)-based strategy for error recovery in MEDA biochips; Includes structural and functional test methods for MEDA biochips; Describes a droplet size-aware sample preparation method, referred to as the weighted sample-preparation method (WSPM), for MEDA biochips.

Contents:

Introduction

MEDA Digital Microfluidic Biochips

Droplet Size-Aware High Level Synthesis

Efficient and Adaptive Error Recovery

Structural and Functional Test Methods

Droplet Size-Aware and Error-Correcting Sample Preparation

Conclusion.

Other Format:

Printed edition:

ISBN:

978-3-030-02964-7

9783030029647

OCLC:

1079055205

Access Restriction:

Restricted for use by site license.