Computational Intelligence and Pattern Analysis in Biological Informatics / Maulik, Ujjwal.

Format:

Book

Author/Creator:

Maulik, Ujjwal, author.

Bandyopadhyay, Sanghamitra, author.

Wang, Jason, author.

Series:

Wiley series on bioinformatics: computational techniques and engineering

Language:

English

Subjects (All):

Bioinformatics.

Computational biology.

Artificial intelligence.

Pattern recognition systems.

Physical Description:

1 online resource (372 pages)

Edition:

1st edition

Place of Publication:

Wiley, 2010.

System Details:

text file

Summary:

An invaluable tool in Bioinformatics, this unique volume provides both theoretical and experimental results, and describes basic principles of computational intelligence and pattern analysis while deepening the reader's understanding of the ways in which these principles can be used for analyzing biological data in an efficient manner. This book synthesizes current research in the integration of computational intelligence and pattern analysis techniques, either individually or in a hybridized manner. The purpose is to analyze biological data and enable extraction of more meaningful information and insight from it. Biological data for analysis include sequence data, secondary and tertiary structure data, and microarray data. These data types are complex and advanced methods are required, including the use of domain-specific knowledge for reducing search space, dealing with uncertainty, partial truth and imprecision, efficient linear and/or sub-linear scalability, incremental approaches to knowledge discovery, and increased level and intelligence of interactivity with human experts and decision makers Chapters authored by leading researchers in CI in biology informatics. Covers highly relevant topics: rational drug design; analysis of microRNAs and their involvement in human diseases. Supplementary material included: program code and relevant data sets correspond to chapters. Note: The ebook version does not provide access to the companion files.

Contents:

Computational Intelligence: foundations, perspectives, and recent trends / Swagatam Das, Ajith Abraham, and B. K. Panigrahi

Fundamentals of pattern analysis / Basabi Chakraborty

Biological informatics: data, tools and applications / Kevin Byron, Miguel Cervantes-Cervantes and Jason T. L. Wang

Sequence Analysis

Promoter recognition using neural network approaches / T. Sobha Rani, S. Durga Bhavani and S. Bapi Raju

Predicting microRNA prostate cancer target genes / Francesco Masulli, Stefano Rovetta and Giuseppe Russo

Structural search in RNA motif databases / Dongrong Wen and Jason T. L. Wang

Kernels on protein structures / Sourangshu Bhattacharya, Chiranjib Bhattacharyya and Nagasuma R. Chandra

Characterization of conformational patterns in active and inactive forms of kinases using protein blocks approach / Garima Agarwal, Dhurvas Chandrasekaran Dinesh, Narayanaswamy Srinivasan, Alexandre G. de Brevern

Kernel applications in cheminformatics / Aaron Smalter and Jun Huan

In-silico drug design using a computational intelligence technique / Soumi Sengupta and Sanghamitra Bandyopadhyay

Integrated differential fuzzy clustering for analysis of microarray data / Indrajit Saha and Ujjwal Maulik

Identifying potential gene markers using SVM classifier ensemble / Anirban Mukhopadhyay, Ujjwal Maulik and Sanghamitra Bandyopadhyay

Gene microarray data analysis using parallel point symmetry-based clustering / Ujjwal Maulik and Anasua Sarker

Techniques for prioritization of possible disease genes / Jieun Jeong and Jake Y. Chen

Prediction of protein protein interactions / Angshuman Bagchi

Analyzing topological properties of protein-protein interaction networks / Malay Bhattacharyya and Sanghamitra Bandyopadhyay.

Notes:

Includes bibliographical references and index.

Online resource; Title from title page (viewed November 30, 2010)

OCLC:

829395454