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Current Immunotherapeutic Strategies in Cancer / edited by Matthias Theobald.

LIBRA RC261 .R35 v.1 (1965)-v.5 (1966), v.7 (1966)-v.98 (1985), v.100 (1986)-v.121 (1991), v.123 (1991)-v.126 (1993), v.128 (1993)-v.158 (2000); v.13:2nd ed. (1976) 1969
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Format:
Book
Contributor:
Theobald, Matthias, editor.
SpringerLink (Online service)
Series:
Medicine (Springer-11650)
Recent results in cancer research 0080-0015 ; 214.
Recent Results in Cancer Research, 0080-0015 ; 214
Language:
English
Subjects (All):
Oncology.
Immunology.
Local Subjects:
Oncology.
Immunology.
Physical Description:
1 online resource (V, 187 pages).
Edition:
First edition 2020.
Contained In:
Springer eBooks
Place of Publication:
Cham : Springer International Publishing : Imprint: Springer, 2020.
System Details:
text file PDF
Summary:
This book offers a comprehensive review of recent advances in cancer immunotherapy, and explores the value and limitations of the most effective current therapeutic strategies and emerging treatment modalities. It discusses in detail the successes achieved using monoclonal antibodies (mAbs), including developments with regard to conjugated mAbs and also bispecific mAbs as novel treatment options for leukemia and solid tumors. It also examines the advances toward personalized immunotherapy, focusing on the effectiveness of adoptive cell therapy using genetically engineered T cells with tumor-associated antigen-specific T-cell receptors and chimeric antigen receptors, as well as the role of tailored vaccines based on the patient's cancer mutanome. Further, it describes the impressive therapeutic results recently achieved with checkpoint inhibitors, and analyzes novel strategies to modulate the immunosuppressive tumor microenvironment. Written by leading international experts and providing up-to-date information on emerging strategies, such as oncolytic virus-based therapy, epigenetic therapy, and combination therapy, the book appeals to all those with an interest in immunotherapy as it comes of age.
Contents:
Current Development of Monoclonal Antibodies in Cancer Therapy
Clinical Experience with Bispecific T-Cell Engagers
Advances and challenges of CAR-modified T cells in clinical trials
Targeting Cancer with Genetically Engineered TCR-T Cells
Tailored Vaccines Based on Patient's Cancer Mutanome
Next-Generation Checkpoint Inhibitors and Immune Agonists.
Other Format:
Printed edition:
ISBN:
978-3-030-23765-3
9783030237653
Access Restriction:
Restricted for use by site license.

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