Tumor immunology and immunotherapy - integrated methods. Part A / edited by Lorenzo Galluzzi, Nils-Petter Rudqvist.

Format:

Book

Contributor:

Galluzzi, Lorenzo, editor.

Rudqvist, Nils-Petter, editor.

Series:

Methods in enzymology ; Volume 630.

Methods in enzymology ; Volume 630

Language:

English

Subjects (All):

Tumors--Immunological aspects.

Tumors.

Physical Description:

1 online resource (346 pages).

Place of Publication:

Cambridge, Massachusetts : Academic Press, [2020]

Summary:

Tumor Immunology and Immunotherapy Integrated Methods - Part A, Volume 635 in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. Specific chapters to this release include Deconvolution of the immunological contexture of mouse tumors with multiplexed immunohistochemistry, High-dimensional multiplexed immunohistochemical characterization of immune contexture in human cancers, Multiplex assay by IHC for melanoma tumor microenvironment evaluation, Characterization of the tumor immune microenvironment by multispectral image analysis of multiplex immunofluorescence images, Phenotyping of immune cells in situ using multispectral imaging quantification, and much more.- Authored by leaders in the field of enzymology- Provides a comprehensiveness level of discussion on the field- Presents a highly specialized group of topics that delve deep into new updates and future prospects

Contents:

High-dimensional multiplexed immunohistochemical characterization of immune contexture in human cancers / Grace Banik, Courtney B. Betts, Shannon M. Liudahl, Shamilene Sivagnanam, Rie Kawashima, Tiziana Cotechini, William Larson, Jeremy Goecks, Sara I. Pai, Daniel R. Clayburgh, Takahiro Tsujikawa and Lisa M. Coussens

Multiplex immunohistochemistry assay to evaluate the melanoma tumor microenvironment / Giosuè Scognamiglio, Mariaelena Capone, Domenico Mallardo, Gerardo Botti, Paolo A. Ascierto and Gabriele Madonna

Characterization of the immune microenvironment of NSCLC by multispectral analysis of multiplex immunofluorescence images / Michael Surace, Lorenz Rognoni, Jaime Rodriguez-Canales and Keith E. Steele

Multiplexed immunohistochemistry for immune cell phenotyping, quantification and spatial distribution in situ / Angela Vasaturo and Jérôme Galon

Multiplex immunohistochemistry as a novel tool for the topographic assessment of the bone marrow stem cell niche / Marcus Bauer, Christoforos Vaxevanis, Daniel Bethmann, Chiara Massa, Nikolaos Pazaitis, Claudia Wickenhauser and Barbara Seliger

Deconvolution of the immunological contexture of mouse tumors with multiplexed immunohistochemistry / Ileana S. Mauldin, Natasha D. Sheybani, Samuel J. Young, Richard J. Price and Craig L. Slingluff

Tracing bone marrow-derived microglia in brain metastatic tumors / Wei Du and Paula D. Bos

Monitoring abscopal responses to radiation in mice / Maria Esperanza Rodriguez-Ruiz, Takahiro Yamazaki, Aitziber Buqué, Norma Bloy, Viviane A. O. Silva, Lena Stafford, Ai Sato and Lorenzo Galluzzi

Methods to assess anticancer immune responses in orthotopic bladder carcinomas / Randy F. Sweis

Characterization of conventional dendritic cell populations in preclinical tumor models using flow cytometry / Erik Wennerberg, Nils Rudqvist and Sheila Spada

Quantitative evaluation of tumor-specific T cells in tumors and lymphoid tissues / Kathleen M. Kokolus, Nataša Obermajer and Pawel Kalinski

Generation and validation of recombinant herpes simplex type 1 viruses (HSV-1) using CRISPR/Cas9 genetic disruption / Praveen K. Bommareddy, Cole Peters and Howard L. Kaufman

Production and use of adeno-associated virus vectors as tools for cancer immunotherapy / Myriam Fernandez-Sendin, Shirley Tenesaca, Marcos Vasquez, Fernando Aranda and Pedro Berraondo

Modulation of the tumor microenvironment with an oncolytic adenovirus for effective T-cell therapy and checkpoint inhibition / João Manuel Santos, Riikka Havunen and Akseli Hemminki

Genetic modification of oncolytic viruses to enhance antitumor immunity / Maria Eugenia Davola, Alyssa Vito, Jiarun Wei, Nader El-Sayes, Samuel Workenhe and Karen Louise Mossman

CRISPR technology for immuno-oncology applications / Jianbin Wang, Vitaly Balan and Francesco Marincola

Neoantigen prediction from genomic and transcriptomic data / Sebastiano Battaglia

Monitoring antigen cross-presentation with human dendritic cells purified from the blood / Stephane Isnard, Etienne Hatton, Jean-Baptiste Guillerme and Anne Hosmalin.

Notes:

Description based on print version record.

ISBN:

0-12-818875-8

0-12-818677-1